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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
ACVR1/ALK2
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "ACVR1/ALK2" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
ALK2-IN-2 is an orally active and selective inhibitor of ALK2 (ACVR1), with an IC50 value of 9 nM, and over 700-fold selectivity against ALK3. ALK2-IN-2 can inhibit oxidative stress and protect endothelial cells [1] [2].
Synonyms: TP-0184
Research Areas:
Itacnosertib (TP-0184) is the inhibitor for FLT3, ACVR1 (ALK2, IC50=8 nM) and JAK2 (IC50=8540 nM). Itacnosertib exhibits anti-leukemic activity [1] [2].
Synonyms: TP-0184 hydrochloride
Research Areas:
Itacnosertib hydrochloride (TP-0184 hydrochloride) is the inhibitor for FLT3, ACVR1 (ALK2, IC50=8 nM) and JAK2 (IC50=8540 nM). Itacnosertib hydrochloride exhibits anti-leukemic activity [1] [2].
Cat. No.: HY-P990022
CAS No.: 2566473-71-8
Synonyms: DS-6016A
Target:
Research Areas:
Cat. No.: HY-109179AR
CAS No.: 2409543-84-4
Synonyms: TP-0184 hydrochloride (Standard)
Target:
JAK Reference Standards Anaplastic lymphoma kinase (ALK) FLT3 STAT PI3K Akt mTOR TGF-beta/Smad TGF-β Receptor
Research Areas:
Itacnosertib hydrochloride (Standard) is the analytical standard of Itacnosertib (hydrochloride) (HY-109179A). This product is intended for research and analytical applications. Itacnosertib hydrochloride (TP-0184 hydrochloride) is the inhibitor for FLT3, ACVR1 (ALK2, IC50=8 nM) and JAK2 (IC50=8540 nM). Itacnosertib hydrochloride exhibits anti-leukemic activity [1] [2].
Cat. No.: HY-109179R
CAS No.: 1628870-27-8
Synonyms: TP-0184 (Standard)
Target:
Reference Standards JAK Anaplastic lymphoma kinase (ALK) FLT3 STAT PI3K Akt mTOR TGF-beta/Smad TGF-β Receptor
Research Areas:
Itacnosertib (Standard) is the analytical standard of Itacnosertib (HY-109179). This product is intended for research and analytical applications. Itacnosertib (TP-0184) is the inhibitor for FLT3, ACVR1 (ALK2, IC50=8 nM) and JAK2 (IC50=8540 nM). Itacnosertib exhibits anti-leukemic activity [1] [2].
Cat. No.: HY-P705731
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-1; ACTR-I; ALK-2; SKR1; TSR-I; ACVR1; ACVRLK2
Species:
Source:
Cat. No.: HY-P705993
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-1; ACTR-I; ALK-2; SKR1; TSR-I; ACVR1; ACVRLK2
Species:
Source:
Cat. No.: HY-P705732
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-1; ACTR-I; ALK-2; SKR1; TSR-I; ACVR1; ACVRLK2
Species:
Source:
Cat. No.: HY-P705733
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-1; ACTR-I; ALK-2; SKR1; TSR-I; ACVR1; ACVRLK2
Species:
Source:
Cat. No.: HY-P705734
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-1; ACTR-I; ALK-2; SKR1; TSR-I; ACVR1; ACVRLK2
Species:
Source:
Cat. No.: HY-P705735
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-1; ACTR-I; ALK-2; SKR1; TSR-I; ACVR1; ACVRLK2
Species:
Source:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
