4 Results for "

ASN 002

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "ASN 002" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-103018
CAS No.: 1425381-60-7
Purity:  99.41%
Synonyms: ASN-002
Target:  

JAK Syk

Research Areas:  

Inflammation/Immunology Cancer

Gusacitinib (ASN-002) is an orally active dual SYK/JAK kinase inhibitor with IC50 values of 5, 46, 4, 11 and 8 nM for SYK, JAK1, JAK2, JAK3 and TYK2, respectively. Gusacitinib rapidly and significantly suppressed key inflammatory pathways implicated in atopic dermatitis pathogenesis. Gusacitinib can be used in the research of chronic hand eczema and cancers such as basal cell carcinoma .
loading...
    loading...
Cat. No.: HY-103018A
CAS No.: 2228989-14-6
Synonyms: ASN-002 hydrochloride
Target:  

JAK Syk

Research Areas:  

Inflammation/Immunology Cancer

Gusacitinib (ASN-002) hydrochloride is an orally active dual SYK/JAK kinase inhibitor with IC50 values of 5, 46, 4, 11 and 8 nM for SYK, JAK1, JAK2, JAK3 and TYK2, respectively. Gusacitinib hydrochloride rapidly and significantly suppressed key inflammatory pathways implicated in atopic dermatitis pathogenesis. Gusacitinib hydrochloride can be used in the research of chronic hand eczema and cancers such as basal cell carcinoma .
loading...
    loading...
Cat. No.: HY-103018R
CAS No.: 1425381-60-7
Synonyms: ASN-002 (Standard)
Research Areas:  

Inflammation/Immunology Cancer

Gusacitinib (Standard) is the analytical standard of Gusacitinib (HY-103018). This product is intended for research and analytical applications. Gusacitinib (ASN-002) is an orally active dual SYK/JAK kinase inhibitor with IC50 values of 5, 46, 4, 11 and 8 nM for SYK, JAK1, JAK2, JAK3 and TYK2, respectively. Gusacitinib rapidly and significantly suppressed key inflammatory pathways implicated in atopic dermatitis pathogenesis. Gusacitinib can be used in the research of chronic hand eczema and cancers such as basal cell carcinoma .
loading...
    loading...
Cat. No.: HY-103018S
Synonyms: ASN-002-d4
Gusacitinib-d4 (ASN-002-d4) is the deuterium labeled Gusacitinib (HY-103018). Gusacitinib (ASN-002) is an orally active dual SYK/JAK kinase inhibitor with IC50 values of 5, 46, 4, 11 and 8 nM for SYK, JAK1, JAK2, JAK3 and TYK2, respectively. Gusacitinib rapidly and significantly suppressed key inflammatory pathways implicated in atopic dermatitis pathogenesis. Gusacitinib can be used in the research of chronic hand eczema and cancers such as basal cell carcinoma .
loading...
    loading...