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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
Adenosine Deaminase Inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "Adenosine Deaminase Inhibitor" in MCE Product Catalog:
11
11 Publications Verification
Synonyms: 2-Chloro-2′-deoxyAdenosine; CldAdo; 2CdA
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Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis .
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Pentostatin (CI-825; Deoxycoformycin) is an irreversible inhibitor of adenosine deaminase with Ki of 2.5 pM.
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5 Cited Publications
Research Areas:
Infection Cardiovascular Disease Neurological Disease Cancer
EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4 μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects .
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1 Cited Publications
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AMPD2 inhibitor 1 is an adenosine monophosphate deaminase 2 (AMPD2) inhibitor, used in the research of sugar craving, salt craving, umami craving, and addictions including agent, tobacco, nicotine and alcohol addictions.
Cat. No.: HY-N7368
CAS No.: 55366-56-8
Category:
Flavonols other families Flavonoids Neurological Disease Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology
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1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a Ki value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders .
Cat. No.: HY-120248
CAS No.: 256461-28-6
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FR221647 is an orally active non-nucleoside inhibitor of adenosine deaminase. FR221647 is not cytotoxic at a concentration of 100 μM .
Cat. No.: HY-19130
CAS No.: 143153-93-9
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BW-534U87 is an orally active adenosine A1 receptor agonist and competitive adenosine deaminase (ADA) inhibitor (Ki=7 μM). BW-534U87 elevates brain adenosine levels and suppresses epileptiform activity. BW-534U87 demonstrate anticonvulsant efficacy in animal seizure models. BW-534U87 is promising for research of epilepsy and adenosine-related neuropsychiatric disorders .
Synonyms: 2-Chloro-2′-deoxyAdenosine (Standard); CldAdo (Standard); 2CdA (Standard)
Research Areas:
Cladribine (Standard) is the analytical standard of Cladribine. This product is intended for research and analytical applications. Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis .
Cat. No.: HY-103160B
CAS No.: 51350-19-7
Research Areas:
Infection Cardiovascular Disease Neurological Disease Cancer
EHNA is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4 μM) and adenosine deaminase (ADA). EHNA exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects .
Cat. No.: HY-122154
CAS No.: 256461-79-7
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FR234938 is a non-nucleoside adenosine deaminase inhibitor with an IC50 of 17 nM for recombinant human adenosine deaminase enzyme. FR234938 has anti-rheumatic and anti-inflammatory effects .
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Bupirimate is a systemic fungicide that inhibits adenosine deaminase (ADA). Bupirimate is widely used in the cultivation of fruit trees, vegetables, flowers, and other crops to control powdery mildew .
Cat. No.: HY-A0006R
CAS No.: 53910-25-1
Synonyms: CI-825 (Standard); Deoxycoformycin (Standard)
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Pentostatin (Standard) is the analytical standard of Pentostatin. This product is intended for research and analytical applications. Pentostatin (CI-825; Deoxycoformycin) is an irreversible inhibitor of adenosine deaminase with Ki of 2.5 pM.
Cat. No.: HY-133216R
CAS No.: 41483-43-6
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Bupirimate (Standard) is the analytical standard of Bupirimate (HY-133216). This product is intended for research and analytical applications. Bupirimate is a systemic fungicide that inhibits adenosine deaminase (ADA). Bupirimate is widely used in the cultivation of fruit trees, vegetables, flowers, and other crops to control powdery mildew .
Cat. No.: HY-161703
CAS No.: 157309-10-9
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2-Hydroxy-3′-O-methyladenosine is a synthetic intermediate product that can be used in the research of ischemic heart disease, cerebrovascular disease, kidney disease, inflammatory allergies and other diseases. 2-phenylamino-N6,2'-O-dimethyladenosine produced from 2-Hydroxy-3′-O-methyladenosine is an inhibitor of adenosine deaminase with a Ki of 13 nM .
Cat. No.: HY-13599S
Synonyms: 2-Chloro-2′-deoxyAdenosine-d4; CldAdo-d4; 2CdA-d4
Cat. No.: HY-13599S2
CAS No.: 1360874-38-9
Synonyms: 2-Chloro-2′-deoxyAdenosine-15N; Cldado-15N; 2Cda-15N
Cat. No.: HY-13599S1
Synonyms: 2-Chloro-2′-deoxyAdenosine-13C5,15N2; CldAdo-13C5,15N2; 2CdA-13C5,15N2
Cat. No.: HY-N7368R
CAS No.: 55366-56-8
Category:
Flavonols other families Flavonoids Phenols Polyphenols Plants
Cat. No.: HY-103673R
CAS No.: 2139356-35-5
Research Areas:
AMPD2 inhibitor 1 (Standard) is the analytical standard of AMPD2 inhibitor 1 (HY-103673). This product is intended for research and analytical applications. AMPD2 inhibitor 1 is an adenosine monophosphate deaminase 2 (AMPD2) inhibitor, used in the research of sugar craving, salt craving, umami craving, and addictions including agent, tobacco, nicotine and alcohol addictions.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
