263 Results for "

Antiviral effects

" in MedChemExpress (MCE) Product Catalog:
Products (263)

263 Results for "Antiviral effects" in MCE Product Catalog:

105
105 Publications Verification
Cat. No.: HY-13605
CAS No.: 147-94-4
Purity:  99.98%
Synonyms: Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C
Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity.
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105
105 Publications Verification
Cat. No.: HY-13605A
CAS No.: 69-74-9
Purity:  99.67%
Synonyms: Cytosine β-D-arabinofuranoside hydrochloride; Cytosine Arabinoside hydrochloride; Ara-C hydrochloride
Cytarabine hydrochloride, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine hydrochloride has antiviral effects against HSV.
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60
60 Cited Publications
Cat. No.: HY-B0180
CAS No.: 99011-02-6
Synonyms: R 837
Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 .
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60
60 Cited Publications
Cat. No.: HY-B0180A
CAS No.: 99011-78-6
Synonyms: R 837 hydrochloride
Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19 .
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60
60 Cited Publications
Cat. No.: HY-B0180B
CAS No.: 896106-16-4
Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19 .
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51
51 Cited Publications
Cat. No.: HY-13524
CAS No.: 153436-53-4
Purity:  99.57%
Synonyms: Tyrphostin AG-1478; NSC 693255
AG-1478 (Tyrphostin AG-1478) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 has antiviral effects against HCV and encephalomyocarditis virus (EMCV).
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35
35 Cited Publications
Cat. No.: HY-N0191
CAS No.: 5508-58-7
Synonyms: Andrographis
Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects.
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34
34 Cited Publications
Cat. No.: HY-107454
CAS No.: 887686-02-4
Purity:  98.63%
OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC50s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects .
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21
21 Cited Publications
Cat. No.: HY-U00434
CAS No.: 890405-51-3
Target:  

mTOR Autophagy Apoptosis

Research Areas:  

Infection Inflammation/Immunology

3BDO is a IFITM3 modulator and mTOR activator with antiviral and autophagy-inhibiting effects. 3BDO exhibits inhibitory activity against porcine coronaviruses. 3BDO increases the protein abundance of IFITM3, inhibits virus-cell membrane fusion, and blocks viral entry. 3BDO inhibits the entry of transmissible gastroenteritis virus, porcine epidemic diarrhea virus, and porcine respiratory coronavirus into host cells. 3BDO can be used for research on porcine coronavirus infection .
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19
19 Cited Publications
Cat. No.: HY-B0097
CAS No.: 50-91-9
Synonyms: 5-Fluorouracil 2'-deoxyriboside
Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis . Floxuridine has antiviral effects against HSV and CMV .
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17
17 Cited Publications
Cat. No.: HY-13666
CAS No.: 16595-80-5
Purity:  99.86%
Synonyms: (-)-Tetramisole hydrochloride
Target:  

Parasite HSV

Research Areas:  

Infection Neurological Disease Cancer

Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV.
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15
15 Cited Publications
Cat. No.: HY-D0803
CAS No.: 490-91-5
Thymoquinone is an orally active natural product isolated from N. sativa Thymoquinone down-regulates the VEGFR2-PI3K-Akt pathway. Thymoquinone has antioxidant, anti-inflammatory, anticancer, antiviral, anticonvulsant, antifungal, antiviral, antiangiogenic activity and hepatoprotective effects. Thymoquinone can be used to study Alzheimer's disease, cancer, cardiovascular disease, infectious disease and inflammation .
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14
14 Cited Publications
Cat. No.: HY-B0421
CAS No.: 24280-93-1
Synonyms: Mycophenolate
Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 µM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects .
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14
14 Cited Publications
Cat. No.: HY-B0421A
CAS No.: 37415-62-6
Synonyms: Mycophenolate sodium
Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 µM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects .
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13
13 Cited Publications
Cat. No.: HY-17015A
CAS No.: 330600-85-6
Synonyms: RWJ-270201; BCX-1812
Target:  

IKK JNK STAT p38 MAPK ERK

Research Areas:  

Infection Inflammation/Immunology

Peramivir is an novel cyclopentane neuraminidase inhibitor of influenza virus. Peramivir has antiviral activity and anti-cytokines stom effects. Peramivir can be used for the research of COVID-19 .
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11
11 Cited Publications
Cat. No.: HY-N0328
CAS No.: 6147-11-1
Synonyms: α-Mangostin
alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.
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10
10 Cited Publications
Cat. No.: HY-112163
CAS No.: 2098191-53-6
Purity:  99.69%
Synonyms: eFT226
Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex . Zotatifin shows robust antiviral effects, it effectively reduces viral infectivity by inhibiting SARS-CoV-2 NP protein biogenesis (IC90=37 nM) . Zotatifin induces cell apoptosis .
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7
7 Cited Publications
Cat. No.: HY-N0012
CAS No.: 40246-10-4
Synonyms: Glycitein 7-O-β-glucoside
Glycitin (Glycitein 7-O-β-glucoside) is a natural isoflavone with antibacterial, antiviral, anticancer, anti-inflammation, anti-aging and estrogenic effects. Glycitin may regulate osteoblasts through TGF-β or AKT signaling pathways in bone marrow stem cells (BMSCs) .
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7
7 Cited Publications
Cat. No.: HY-129555
CAS No.: 252023-70-4
Purity:  98.96%
Surfactin is a potent cyclic lipopeptide biosurfactants consists of four isomers (Surfactin A, B, C and D), which mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. Surfactin can act as an antimicrobial adjuvant with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects . Surfactin also has antiviral activity against a variety of enveloped viruses .
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6
6 Cited Publications
Cat. No.: HY-N2022
CAS No.: 79831-76-8
Castanospermine is a natural alkaloid that can be extracted from black beans or the Moreton Bay chestnut tree (Castanospermum australae). Castanospermine is an α/ β-glucosidase inhibitor. Castanospermine has anti-inflammatory, antiviral replication and anti-metastatic effects on prostate cancer. Castanospermine can be used as an immunosuppressant to prevent transplant rejection .
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