3 Results for "

CB659

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "CB659" in MCE Product Catalog:

Cat. No.: HY-100867A
CAS No.: 1952251-28-3
Purity:  99.86%
Synonyms: TAK-659 monohydrochloride; CB-659 monohydrochloride
Target:  

Syk FLT3

Research Areas:  

Cancer

TAK-659 hydrochloride is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. TAK-659 hydrochloride induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL) .
loading...
    loading...
Cat. No.: HY-100867
CAS No.: 1312691-33-0
Synonyms: TAK-659; CB-659
Target:  

Syk FLT3

Research Areas:  

Cancer

TAK-659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. TAK-659 induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL) .
loading...
    loading...
Cat. No.: HY-100867AR
CAS No.: 1952251-28-3
Synonyms: TAK-659 monohydrochloride (Standard); CB-659 monohydrochloride (Standard)
Research Areas:  

Cancer

Mivavotinib (monohydrochloride) (Standard) is the analytical standard of Mivavotinib (monohydrochloride) (HY-100867A). This product is intended for research and analytical applications. TAK-659 hydrochloride is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. TAK-659 hydrochloride induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL) .
loading...
    loading...