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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
D5R
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "D5R" in MCE Product Catalog:
Art. -Nr.: HY-169116
Target:
Forschungsgebiete:
D5R agonist 1 (Compound 5j) is a selective, orally active and BBB penetrable D5R partial agonist (EC50: 269.7 nM). D5R agonist 1 enhances the cognition in the Scopolamine (HY-N0296)-induced amnesia model .
Art. -Nr.: HY-175504
CAS. Nr.: 932544-59-7
Target:
Forschungsgebiete:
MLS6357 is a D3 dopamine receptor (D3R)-selective positive allosteric modulator (PAM)-antagonist. MLS6357 exhibits antagonist activity in the D3R-mediated and the BRET-based β-arrestin recruitment assay with IC50s of 13 and 14 μM, and no activity for other DAR subtypes (D1R/D2R/D4R/D5R) (IC50 > 100 μM). MLS6357 is also an antagonist in the D3R-mediated Go-BRET assay with an IC50 of 17 μM. MLS6357 can be used for the study of neuropsychiatric disorders, including substance use disorder .
Art. -Nr.: HY-18259
CAS. Nr.: 773852-25-8
Target:
Forschungsgebiete:
103D5R (Compound 15) is an inhibitor for the activation of hypoxia-inducible factor-1 (HIF-1) with an IC50 of 35 µM, through reduction of the HIF-1α protein synthesis. 103D5R inhibits the proliferation of LN229 with IC50 of 26 µM .
Art. -Nr.: HY-152678
Forschungsgebiete:
6-Methoxypurine-9-β-D-5’(R)-C-methylriboside is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
Art. -Nr.: HY-RS04007
Target:
Forschungsgebiete:
Drd5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Drd5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-17385S
Synonyms: Tomoxetine-d5 hydrochloride; LY 139603-d5 ; (R)-Tomoxetine-d5 hydrochloride
Art. -Nr.: HY-W738480
CAS. Nr.: 1177315-89-7
Synonyms: (R)-Tert-Butyl 2-amino-3-phenylpropanoate-d5
Art. -Nr.: HY-W704363
CAS. Nr.: 1794979-08-0
Synonyms: R6238-d5
Art. -Nr.: HY-125527AS
Synonyms: 17(R)-RvD1-d5; AT-RvD1-d5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
