1 Result for "

DHTP

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DHTP" in MCE Product Catalog:

製品番号: HY-177898
CAS 番号: 1620225-37-7
Target:  

Kinesin

研究分野:  

Cancer

DHTP is a kinesin-13 family of microtubule depolymerases selective allosteric inhibitor that inhibits kinesin-13 ATPase activity and microtubule depolymerization activity. DHTP inhibits Kif2a and MCAK with IC50 values of 1.2 μM and 4.6 μM, respectively, and does not inhibit other kinesin families. DHTP modulates microtubule dynamics in cells, leading to less dynamic microtubules. DHTP links kinesin-13 overexpression to cancer and Paclitaxel (HY-B0015) resistance. DHTP can be used for the research of cancer .
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