Dioleoylphosphatidylethanolamine

標的別:	ACSL Family (1) Amino acid Transporter (1) Biochemical Assay Reagents (2) Endogenous Metabolite (2) Ferroptosis (1) Glutathione Peroxidase (1) Isotope-Labeled Compounds (1) Liposome (3)
研究分野別:	Cancer (1) Inflammation/Immunology (4) Neurological Disease (1)
Oligonucleotides:	Cationic Lipids (1) Phospholipids (1)

製品番号	製品名	Target	研究分野	構造式

HY-112005

DOPE 5+ Cited Publications Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine	Liposome Endogenous Metabolite	Inflammation/Immunology
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-W590549

Dioleyldimethylammonium chloride DODAC	Liposome	Cancer
Dioleyldimethylammonium chloride (DODAC) is a positively charged lipid promoter with membrane-disrupting activity, which is often formulated into cationic liposomes with dioleoylphosphatidylethanolamine. Dioleyldimethylammonium chloride is used in gene transfection research; through electrostatic interactions, it effectively promotes the binding of programmable fusion vesicles to cells and induces membrane disruption. Dioleyldimethylammonium chloride is also applied in studies on L1210 leukemia and LS180 human colon cancer .

HY-112005GL

DOPE (GMP Like) Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)	Liposome Endogenous Metabolite	Inflammation/Immunology
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-112005S

DOPE-d62 Dioleoylphosphatidylethanolamine-d₆₂; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-d₆₂	Isotope-Labeled Compounds	Inflammation/Immunology
DOPE-d₆₂ (Dioleoylphosphatidylethanolamine-d₆₂) is the deuterium labeled DOPE (HY-112005). DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-112005G

DOPE Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine	Ferroptosis Glutathione Peroxidase ACSL Family Amino acid Transporter	Neurological Disease Inflammation/Immunology
DOPE GMP is DOPE (HY-112005) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .

HY-W1053112B

DOPE-PEG10000-Amine DOPE-PEG10000-NH2	Biochemical Assay Reagents	Others
DOPE-PEG10000-Amine (DOPE-PEG1000-NH2) is a conjugate composed of dioleoylphosphatidylethanolamine (DOPE), a PEG chain, and a terminal amino group (-NH2). The amino group in DOPE-PEG10000-Amine can chemically react with carboxyl groups, activated esters, etc., participating in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.

HY-W440990

DOPE-PEG1000-Amine DOPE-PEG1000-NH2	Biochemical Assay Reagents	Others
DOPE-PEG1000-Amine (DOPE-PEG1000-NH2) is a conjugate composed of dioleoylphosphatidylethanolamine (DOPE), a PEG chain, and a terminal amino group (-NH2). The amino group in DOPE-PEG1000-Amine can chemically react with carboxyl groups, activated esters, etc., participating in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.

製品番号	製品名	Type

HY-112005GL

DOPE (GMP Like) Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)	蛍光色素
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-112005G

DOPE Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine	蛍光色素
DOPE GMP is DOPE (HY-112005) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .

DOPE

Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

蛍光色素

DOPE GMP is DOPE (HY-112005) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .

製品番号	製品名	Type

HY-112005

DOPE 5+ Cited Publications Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine	生化学アッセイ試薬
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-112005GL

DOPE (GMP Like) Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)	生化学アッセイ試薬
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-112005G

DOPE Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine	生化学アッセイ試薬
DOPE GMP is DOPE (HY-112005) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .

DOPE

Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

生化学アッセイ試薬

DOPE GMP is DOPE (HY-112005) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .

HY-W1053112B

DOPE-PEG10000-Amine DOPE-PEG10000-NH2	生化学アッセイ試薬
DOPE-PEG10000-Amine (DOPE-PEG1000-NH2) is a conjugate composed of dioleoylphosphatidylethanolamine (DOPE), a PEG chain, and a terminal amino group (-NH2). The amino group in DOPE-PEG10000-Amine can chemically react with carboxyl groups, activated esters, etc., participating in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.

HY-W440990

DOPE-PEG1000-Amine DOPE-PEG1000-NH2	生化学アッセイ試薬
DOPE-PEG1000-Amine (DOPE-PEG1000-NH2) is a conjugate composed of dioleoylphosphatidylethanolamine (DOPE), a PEG chain, and a terminal amino group (-NH2). The amino group in DOPE-PEG1000-Amine can chemically react with carboxyl groups, activated esters, etc., participating in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.

製品番号	製品名	構造式

HY-112005S

DOPE-d62
DOPE-d₆₂ (Dioleoylphosphatidylethanolamine-d₆₂) is the deuterium labeled DOPE (HY-112005). DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

製品番号	製品名		Classification

HY-112005

DOPE 5+ Cited Publications Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine		Phospholipids
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-W590549

Dioleyldimethylammonium chloride DODAC		Cationic Lipids
Dioleyldimethylammonium chloride (DODAC) is a positively charged lipid promoter with membrane-disrupting activity, which is often formulated into cationic liposomes with dioleoylphosphatidylethanolamine. Dioleyldimethylammonium chloride is used in gene transfection research; through electrostatic interactions, it effectively promotes the binding of programmable fusion vesicles to cells and induces membrane disruption. Dioleyldimethylammonium chloride is also applied in studies on L1210 leukemia and LS180 human colon cancer .

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