1 Result for "

EC70124

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EC70124" in MCE Product Catalog:

Cat. No.: HY-124067
CAS No.: 1185908-92-2
Target:  

IKK JAK STAT NF-κB

Research Areas:  

Cancer

EC-70124 is an orally active multikinase inhibitor targeting IKKβ and JAK2. EC-70124 blocks IkB phosphorylation and STAT3 (Tyr705) activation, suppressing NF-κB nuclear translocation and STAT3 transcriptional activity. EC-70124 reduces tumor growth and cancer stem cell (CSC) populations in prostate cancer cells and xenograft models. EC-70124 is promising for research of prostate cancer .
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