2 Results for "

ET-18-O-OCH3

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ET-18-O-OCH3" in MCE Product Catalog:

Cat. No.: HY-134070
CAS No.: 78858-44-3
Synonyms: ET-18-O-OCH3
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

2-O-Methyl PAF C-16 (ET-18-O-OCH3), a structural analog of the mediator of inflammation platelet-activating factor (PAF), is a cytotoxic ether lipid. 2-O-Methyl PAF C-16 stimulates TNF-α release in murine macrophages .
loading...
    loading...
Cat. No.: HY-P11860
Target:  

nAChR

Research Areas:  

Neurological Disease

WrFr-OCH3 is a competitive nAChR inhibitor, with IC50 values of 291.9 nM, 25.3 nM, 477.5 nM and 36.5 nM against hα1β1εδ nAChR, hα9α10 nAChR, hα7 nAChR and hα9 nAChR, respectively. WrFr-OCH3 exhibits analgesic and muscle relaxant effects, reduces forelimb grip strength in rats, and alleviates Oxaliplatin (HY-17371)-induced cold allodynia in rats. WrFr-OCH3 can be used in studies related to cold allodynia .
loading...
    loading...