7 Results for "

Eukaryotic elongation factor 2 kinase

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Eukaryotic elongation factor 2 kinase" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-100576
CAS No.: 278603-08-0
Purity:  99.63%
Research Areas:  

Infection Cancer

NH125 is a potent and selective inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K/CaMKIII) with an IC50 of 60 nM for eEF-2K. NH125 kills methicillin-resistant S. aureus (MRSA) persisters by interacting with and disrupting membranes .
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1
1 Cited Publications
Cat. No.: HY-P701676
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EEF2K; EEF-2 kinase; Eukaryotic elongation factor 2 kinase; Calcium/Calmodulin-Dependent Eukaryotic elongation factor-2 kinase; EEF-2K; Calmodulin-Dependent Protein kinase III; CaMKIII; Eukaroytic elongation factor 2 kinase; Calcium/Calmodulin-Dependent E
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-112393
CAS No.: 503473-32-3
Target:  

HIV Src PKA PKC

Research Areas:  

Infection

TX-1918 is an inhibitor for eukaryotic elongation factor 2 kinase (eEF2-K) and Src kinase with IC50 of 0.44 and 4.4 μM, respectively. TX-1918 exhibits cytotoxicity in cell HepG2 and HCT116, with IC50 of 2.07 and 230 μM, respectively. TX-1918 inhibits the C-terminal domain of HIV-1 CA (CA CTD)(IC50 =3.81 μM), and inhibits the viral replication (IC50 =15.16 μM) .
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Cat. No.: HY-P811094
Synonyms: Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, Calcium/calmodulin-dependent Eukaryotic elongation factor 2 kinase, EEF2K

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Rat, Monkey

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Cat. No.: HY-P811035
Synonyms: Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, Calcium/calmodulin-dependent Eukaryotic elongation factor 2 kinase, EEF2K

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Rat, Monkey

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Cat. No.: HY-P86858
Synonyms: C86191 antibody; Calcium/calmodulin dependent Eukaryotic elongation factor 2 antibody; Calcium/calmodulin dependent Eukaryotic elongation factor 2 kinase antibody; Calcium/calmodulin-dependent Eukaryotic elongation factor 2 kinase antibody; Calmodulin dependent protein kinase III antibody; cb365 antibody; EC 2.7.11.20 antibody; eEF 2 kinase antibody; eEF 2K antibody; eEF-2 kinase antibody; C86191 antibody; Calcium/calmodulin dependent Eukaryotic elongation factor 2 antibody; Calcium/calmodulin dependent Eukaryotic elongation factor 2 kinase antibody; Calcium/calmodulin-dependent Eukaryotic elongation factor 2 kinase antibody; Calmodulin dependent protein kinase III antibody; cb365 antibody; EC 2.7.11.20 antibody; eEF 2 kinase antibody; eEF 2K antibody; eEF-2 kinase antibody; eEF-2K antibody; Eef2k antibody; EEF2K protein antibody; EF2K_HUMAN antibody; elongation factor 2 kinase antibody; Eukaryotic elongation factor 2 kinase antibody; fa04b08 antibody; HSU93850 antibody; kinase eEF2K antibody; MGC45041 antibody; SMEF2K antibody; wu:fa04b08 antibody; zgc:100973 antibody;

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-N14094
CAS No.: 2632-29-3
Tubulosine is an alkaloid. Tubulosine can be isolated from Pogonopus tubulosus (DC.) Schumann. Tubulosine is an ATP-competitive, selective JAK3 inhibitor with an IC50 value of 9.9 nM. Tubulosine also inhibits the kinase activities of other JAK family members, the extent of inhibition is less than that of JAK3, with IC50 values of 69.5, 84.9 and 76.3 nM for JAK1, JAK2 and TYK2, respectively. Tubulosine selectively inhibits JAK3 signalling by binding to the ATP-binding site of the kinase of JAK3. Tubulosine induces apoptotic and necrotic/autophagic cell death. Tubulosine inhibits the process of peptide chain elongation by eukaryotic polysomes by, specifically preventing the elongation-factor-2-dependent step of translocation. Tubulosine exhibits anticancer activity in breast cancer cells .
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