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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
Extracellular interface
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "Extracellular interface" in MCE Product Catalog:
Cat. No.: HY-171444
CAS No.: 1493797-28-6
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GSM III is a γ-Secretase complexe (GSEC) modulator. GSM III significantly regulates amyloid-β (Aβ) length at the extracellular interface between the protease (NCT, PSEN) and the substrate APPC99. GSM III can be used for Alzheimer's disease (AD) research .
Cat. No.: HY-179241
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UNC10062 is a dopamine D1 receptor (D1R) positive allosteric modulator. UNC10062 specifically binds to the extracellular allosteric pocket (upper pocket) at the interface of transmembrane helices (TM) 1 and 7 of D1R. UNC10062 can increase dopamine potency and D1R-mediated cAMP production. UNC10062 can be used for the research of neurological disease, such as Parkinson's disease .
Cat. No.: HY-P11796
CAS No.: 1235835-17-2
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MOG 37-46 is a dominant immunodominant CD8 + T cell epitope. As a truncated version of MOG35-55, MOG 37-46 is recognizable by MOG 35-55-specific T cells, and serves as an autoantibody target at the dimer interface of the extracellular domain of myelin oligodendrocyte glycoprotein (MOG). MOG 37-46 stimulates MOG-specific CD8 + T cell lines and proinflammatory CD8 + T cells migrating into the central nervous system (CNS) to produce IFN-γ. MOG 37-46 is applicable to research related to experimental autoimmune encephalomyelitis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
