23 Results for "

Fmoc-N-amido-PEG2-azide

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "Fmoc-N-amido-PEG2-azide" in MCE Product Catalog:

Cat. No.: HY-132099
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Fmoc-N-amido-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Fmoc-N-amido-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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13
13 Publications Verification
Cat. No.: HY-P1005
CAS No.: 201608-14-2
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Ac-DEVD-AFC is a fluorogenic substrate (λex=400 nm, λem=530 nm).
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5
5 Cited Publications
Cat. No.: HY-P1003
CAS No.: 169332-61-0
Target:  

Fluorescent Dye

Research Areas:  

Others

Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm [2] .
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Cat. No.: HY-41189
CAS No.: 863971-53-3
Target:  

ADC Linkers

Research Areas:  

Cancer

Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Val-Cit-PAB-PNP has superior plasma stability comparable to that of non-cleavable linkers [2] .
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Cat. No.: HY-P10303
CAS No.: 2767993-86-0
Synonyms: Cyclo[RGDfK(azide)]
Research Areas:  

Others

Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is the derivative of Cyclo(-RGDfK) (HY-P0023). Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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Cat. No.: HY-P10392AF
Target:  

Wnt β-catenin

Research Areas:  

Cancer

fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .
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Cat. No.: HY-P11295
CAS No.: 3035272-00-2
Target:  

ADC Linkers

Research Areas:  

Cancer

Fmoc-GGFG-PAB-PNP is an ADC linker used in the synthesis of antibody-drug conjugates (ADC) .
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Cat. No.: HY-P10896
CAS No.: 1446005-10-2
Target:  

Bombesin Receptor

Research Areas:  

Cancer

NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT .
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Cat. No.: HY-W019682
CAS No.: 84889-09-8
Research Areas:  

Cancer

Fmoc-FF is a building block. Fmoc-FF-prepared hydrogels and nanogels selectively deliver Dexamethasone (HY-14648) to leukemia cells .
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Cat. No.: HY-P5037
CAS No.: 185213-75-6
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Fmoc-Gly-Pro-Hyp-OH is a tripeptide that can be used in peptide synthesis .
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Cat. No.: HY-P5962
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Fmoc-Gly-Pro-Hyp(OtBu)-OH (TFA) is a tripeptide that can be used in peptide synthesis .
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Cat. No.: HY-169232
Target:  

PROTACs PD-1/PD-L1

Research Areas:  

Cancer

PCC16 chloride is a dual PROTAC degrader targeting DHHC3 and PD-L1, with a DC50 of 0.103 μM for PD-L1 degradation. PCC16 chloride induces DHHC3 degradation via the ubiquitin-proteasome pathway by recruiting the CRBN E3 ubiquitin ligase (E3 ubiquitin ligase). By targeting DHHC3-which is essential for PD-L1 palmitoylation and membrane stability-PCC16 chloride reduces PD-L1 levels, decreases PD-L1 membrane retention time, and impairs its immunosuppressive function. PCC16 chloride enhances anti-tumor immunity by disrupting PD-L1-mediated immunosuppression. PCC16 chloride can be used in the research of immune checkpoint blockade-resistant cancers [2].
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Cat. No.: HY-P5045
CAS No.: 133575-43-6
Research Areas:  

Inflammation/Immunology Cancer

Fmoc-Thr(GalNAc(Ac)3-β-D)-OH inhibits cancer cell growth, through targeting intricate cancer-specific pathways while simultaneously strengthening immunologic response .
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Cat. No.: HY-W1050525
CAS No.: 2377585-15-2
Target:  

ADC Linkers

Research Areas:  

Cancer

Fmoc-Val-Ala-Gly (compound 58a) is a cleavable ADC linker, can be conjugated to the antibody Trastuzumab (HY-P9907) to form an antibody-drug conjugate (ADC) .
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Cat. No.: HY-P5037A
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Fmoc-Gly-Pro-Hyp-OH TFA is a tripeptide that can be used in peptide synthesis .
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Cat. No.: HY-P11504
CAS No.: 3109821-26-0
Research Areas:  

Others

Fmoc-Lys-Gly-Dopa-OH is a tripeptide. Fmoc-Lys-Gly-Dopa-OH forms coacervates in aqueous solution via phase separation. Fmoc-Lys-Gly-Dopa-OH coacervates, with the assistance of Fe 3+, provide a viable material to engineer the surface of mammalian cells .
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Cat. No.: HY-P4613
CAS No.: 130674-54-3
Research Areas:  

Others

Fmoc-D-allo-Thr-OH is a derivative of D-allothreonine (HY-W001959), which is commonly used as a building block in solid-phase peptide synthesis (SPPS) .
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Cat. No.: HY-P12133
CAS No.: 3080063-21-1
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Tapimtrutide is a gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Tapimtrutide can be used for the research of diabetes .
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Cat. No.: HY-P11625
Target:  

RXFP Receptor

Research Areas:  

Cardiovascular Disease

R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .
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Cat. No.: HY-P11830
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

UDA-6 is a potent calcitonin and amylin receptor agonist (DACRA). UDA-6 induces weight loss, improves metabolic and hepatic parameters, and stabilizes active receptor states in obesity rats. UDA-6 can be used for the research of obesity .
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