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Results for "

GPR32

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Natural
Products

2

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS05702
    GPR32 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    GPR32 Human Pre-designed siRNA Set A contains three designed siRNAs for GPR32 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GPR32 Human Pre-designed siRNA Set A
    GPR32 Human Pre-designed siRNA Set A
  • HY-145491
    Resolvin D5

    		ERK NF-κB CCR Inflammation/Immunology
    Resolvin D5 is an anti-inflammatory and analgesic agent produced in M2 macrophages. Resolvin D5 alleviates Paclitaxel (HY-B0015)-induced mechanical allodynia and inflammatory pain by activating the GPR32 receptor, with gender specificity (effective only in male mice) and independence from TRPV1 or TRPA1 channels. Resolvin D5 attenuates LPS-induced ERK phosphorylation and NF-κB nuclear translocation, downregulates proinflammatory mediators such as IL-6 and CCL5, inhibits Th17 cell differentiation and osteoclastogenesis, promotes regulatory T cell differentiation, and shows no cytotoxicity to human monocytes. The level of Resolvin D5 is elevated in arthritic SKG mice, but Resolvin D5 has no effect on dendritic cell differentiation or M1 macrophage polarization, nor does it prevent ZyA-induced arthritis progression. Resolvin D5 is suitable for research related to chemotherapy-induced peripheral neuropathy, inflammatory pain and rheumatoid arthritis .
    Resolvin D5
  • HY-148361
    Fluorogen binding modulator-1

    		FAP Others
    Fluorogen binding modulator-1 (PubChem SID 125240934) is a fluorogen activating protein (FAP)-fluorogen binding modulator with -log EC50s of 6.61 and 6.37 for AM2.2-β2AR and AM2.2-GPR32, respectively .
    Fluorogen binding modulator-1
  • HY-RS26179
    Gpr32 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Gpr32 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gpr32 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Gpr32 Rat Pre-designed siRNA Set A
    Gpr32 Rat Pre-designed siRNA Set A
  • HY-167754
    Resolvin D5 n-3 DPA

    		GPR84 Inflammation/Immunology
    Resolvin D5 n-3 DPA is a Docosapentaenoic acid (DPA) derived specialized proresolving lipid mediator (SPM). Resolvin D5 n-3 DPA is a GPR101, GPR12, and GPR84 agonist with EC50s of 4.6 pM, 14 pM, and 1.5 pM, respectively. Resolvin D5 n-3 DPA possesses potent pro-resolution and anti-inflammatory actions. Resolvin D5 n-3 DPA reduces cell adhesion onto TNF-α-activated human endothelial monolayers. Resolvin D5 n-3 DPA displays potent leukocyte-directed activities, upregulating the ability of neutrophils and macrophages to phagocytose bacteria. Resolvin D5 n-3 DPA can be used for the study of intestinal inflammation .
    Resolvin D5 n-3 DPA

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