1 Result for "

GRWD5769

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GRWD5769" in MCE Product Catalog:

Cat. No.: HY-184499
CAS No.: 2420554-24-9
Target:  

MHC Aminopeptidase

Research Areas:  

Cancer

GRWD5769 is an orally potent ERAP1 inhibitor. GRWD5769 regulates the peptide repertoire presented by MHC-I, alters TCR diversity/clonality, reprograms antigen-experienced T cells, induces novel T cell responses, drives tumor cell killing, and alleviates T cell exhaustion. GRWD5769 can be used in the research of advanced solid malignancies, microsatellite-stable colorectal cancer, non-small cell lung cancer, bladder cancer, hepatocellular carcinoma, head and neck squamous cell carcinoma, and cervical cancer .
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