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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
Galactosylceramide
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "Galactosylceramide" in MCE Product Catalog:
4
4 Cited Publications
Synonyms: α-GalCer; KRN7000
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α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor) .
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Galactosylceramide (GalC) is a galactosylceramide that has been implicated in many physiological and pathological phenomena. For example, important lysosomal storage disorders such as Gaucher disease (GD) and neurodegenerative diseases are characterized by GlcCer accumulation.
1
Cat. No.: HY-P4070
CAS No.: 1188379-43-2
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Cat. No.: HY-115625
CAS No.: 1375078-57-1
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AG-205 is a progesterone receptor membrane component 1 (PGRMC1) antagonist and CGT inhibitor, with an IC50 of 50 μM against rat CGT. AG-205 exhibits antimitotic, antimigratory and anti-invasive activities. AG-205 increases the expression of genes encoding cholesterol biosynthesis pathway or steroidogenic enzymes. AG-205 promotes the regulation of cell cycle by apoptosis and reduces the migratory and invasive capacities of ovarian and breast cancer cells. AG-205 can be used in research related to renal cancer and breast cancer .
Category:
Human Gut Microbiota Metabolites Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields
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Cat. No.: HY-166293
CAS No.: 1056025-00-3
Synonyms: 4-Fluorophenylundecanoyl-α-Galactosylceramide
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7DW8-5 (4-Fluorophenylundecanoyl-α-galactosylceramide) is an ester product.
Cat. No.: HY-125726
CAS No.: 151057-28-2
Synonyms: (3'-sulfo)Galβ-Cer(d18:1/24:1); N-Nervonoyl Sulfatide; C24:1 Sulfatide
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Sulfo galactosylceramide (N-Nervonoyl Sulfatide; C24:1 Sulfatide) is a glycolipid and the major sulfolipid species in mature myelin. Sulfo galactosylceramide interacts with C-type lectins and immunoglobulin-like receptors, with the highest affinity for LMIR5. Sulfo galactosylceramide induces MCP-1 production by basophils but not mast cells, and increases NFAT activation via LMIR5. Sulfo galactosylceramide alleviates symptoms and improves survival in a mouse model of chronic relapsing-remitting experimental autoimmune encephalomyelitis (EAE), and reduces inflammatory lesions and the number of infiltrating mononuclear cells in the lumbar spinal cord of EAE mice.
Cat. No.: HY-145535
CAS No.: 151122-71-3
Synonyms: C24 3'-sulfo Galactosylceramide (d18:1/24:0)
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Cat. No.: HY-165677
CAS No.: 74645-25-3
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C22 Galactosylceramide is a sphingolipid present in the central nervous system, exhibiting elevated levels in the spinal cord of mice on a methionine-restricted diet, while not affecting the brain or liver; furthermore, it has been identified in the postmortem hippocampus of Alzheimer's disease patients.
Cat. No.: HY-D1575
CAS No.: 170212-26-7
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C6 NBD galactosylceramide is an active derivative of galactosylceramide that is tagged with fluorescent C6 nitrobenzoxadiazole (C6 NBD). C6 NBD galactosylceramide can be used as a substrate for neutral β-glycosylceramidase (GCase) to study intracellular localization and metabolism of galactosylceramide (Ex=nm, Em=525) .
Cat. No.: HY-P4902
CAS No.: 724760-19-4
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Cat. No.: HY-165892
CAS No.: 41613-14-3
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Dodecanoyl-galactosylceramide is an ester product.
Cat. No.: HY-142975
CAS No.: 112726-51-9
Synonyms: C15 Galactosylceramide (d18:1/15:0); GalCer(d18:1/15:0)
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N-Pentadecanoyl-psychosine is a glycolipid that can be used in membrane adhesion studies .
Cat. No.: HY-145493
CAS No.: 474942-98-8
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C12 NBD galactosylceramide, fluorescent dye, is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide can be used for the research of imaging .
Cat. No.: HY-137798
CAS No.: 88793-79-7
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Cat. No.: HY-P11293
CAS No.: 1309855-53-5
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Cat. No.: HY-P4757
CAS No.: 108081-77-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
