7 Results for "

GluT substrate

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "GluT substrate" in MCE Product Catalog:

Cat. No.: HY-175674
CAS No.: 2763063-40-5
NGI-235 is an STT3A-selective oligosaccharyltransferase complex OST-A inhibitor. NGI-235 preferentially inhibits OST-A catalytic activity, impairing N-glycosylation of OST-A substrates. NGI-235 causes the hypoglycosylation of both TLR4, GLUT1 and inhibits NF-κB signaling. NGI-235 can be used for the research of inflammation .
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Cat. No.: HY-N6936
CAS No.: 641-12-3
Sennidin A is an anthraquinone derivative and a HCV NS3 helicase inhibitor with an IC50 of 0.8 μM against HCV NS3 helicase. Sennidin A induces Akt phosphorylation at Ser-473 and Thr-308 and promotes GLUT4 translocation to the plasma membrane. Sennidin A inhibits HCV replication. Sennidin A stimulates glucose incorporation and 2-Deoxyglucose uptake in cells. Sennidin A does not induce tyrosine phosphorylation of the insulin receptor or insulin receptor substrate-1. Sennidin A can be used for research on type 2 diabetes and hepatitis C .
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Cat. No.: HY-100838
CAS No.: 117857-95-1
Synonyms: L-CCG III
Target:  

EAAT

Research Areas:  

Neurological Disease

cis-α-(Carboxycyclopropyl)glycine (L-CCG III) is a potent, competitive glutamate uptake inhibitor. cis-α-(Carboxycyclopropyl)glycine is a substrate of glutamate transporters (GluT) (EC50: 13 μM, 2 μM for EAAT 1 and EAAT 2, respectively). cis-α-(Carboxycyclopropyl)glycine inhibits a Na +-dependent high-affinity L-glutamate uptake in glial plasmalemmal vesicles (GPV) and synaptosomes .
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Cat. No.: HY-D3199
CAS No.: 2364376-61-2
NIR-fluorescent glucose is a functional glucose-based fluorescent imaging agent. Conjugated with the nitrobenzoselenadiazole-based SCOTfluor (compound 9), NIR-fluorescent glucose acts as a substrate for GLUT4 and GLUT2 transporters. NIR-fluorescent glucose enables the visualization of glucose uptake in live cells and in vivo .
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Cat. No.: HY-184962
CAS No.: 2415493-70-6
Target:  

GLUT

Research Areas:  

Cancer

Fluorodeoxyglucopyranose is a GLUT1 transporter substrate with facilitated bidirectional plasma membrane transport dependent on substrate gradients and independent of membrane potential. Fluorodeoxyglucopyranose undergoes conjugation to neuropharmaceutical agents and cancer imaging components. Fluorodeoxyglucopyranose can be used for the research of cancer .
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Cat. No.: HY-189288
CAS No.: 2894135-13-6
Pomalidomide-β-D-glucose is an orally active Molecular glue degrader of IKZF1 and CK1α. Pomalidomide-β-D-glucose forms a ternary complex with CRBN and substrate proteins, inducing ubiquitination and proteasomal degradation of IKZF1 and CK1α. Pomalidomide-β-D-glucose undergoes GLUT1-mediated cellular uptake. Pomalidomide-β-D-glucose can be used for research on multiple myeloma .
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Cat. No.: HY-D3410
CAS No.: 2991899-29-5
CDr17 is a GLUT1 substrate and selective fluorescent dye staining M1 microphages. CDr17 utilizes the Gating-Oriented Live-cell Distinction (GOLD) mechanism to enter M1 macrophages (Ex/Em = 646/662 nm) .
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