NIR‐fluorescent glucose
NIR-fluorescent glucose is a functional glucose-based fluorescent imaging agent. Conjugated with the nitrobenzoselenadiazole-based SCOTfluor (compound 9), NIR-fluorescent glucose acts as a substrate for GLUT4 and GLUT2 transporters. NIR-fluorescent glucose enables the visualization of glucose uptake in live cells and in vivo.
For research use only. We do not sell to patients.
- CAS No.: 2364376-61-2
- Formula: C12H14N4O7Se
- Molecular Weight:405.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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GLUT2 |
GLUT4 |
The NIR-fluorescent glucose (100 μM) is a functional substrate of GLUT4 in GLUT4-EGFP HeLa cells, with measurable uptake that is competitively inhibited by excess glucose and enhanced by insulin pre-treatment[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2364376-61-2
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Molecular Weight 405.22
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Formula C12H14N4O7Se
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SMILES
OC[C@H]1O[C@@H](O)[C@H](NC2=CC=C([N+]([O-])=O)C3=N[Se]N=C32)[C@@H](O)[C@@H]1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)