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Art. -Nr.: HY-D3199

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NIR‐fluorescent glucose

NIR-fluorescent glucose is a functional glucose-based fluorescent imaging agent. Conjugated with the nitrobenzoselenadiazole-based SCOTfluor (compound 9), NIR-fluorescent glucose acts as a substrate for GLUT4 and GLUT2 transporters. NIR-fluorescent glucose enables the visualization of glucose uptake in live cells and in vivo.

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CAS. Nr.: 2364376-61-2
Formel: C₁₂H₁₄N₄O₇Se
Molecular Weight:405.22

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

NIR‐fluorescent glucose Chemical Structure

CAS. Nr.: 2364376-61-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

GLUT2

GLUT4

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In Vitro

The NIR-fluorescent glucose (100 μM) is a functional substrate of GLUT4 in GLUT4-EGFP HeLa cells, with measurable uptake that is competitively inhibited by excess glucose and enhanced by insulin pre-treatment^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2364376-61-2
Molecular Weight 405.22
Formel C₁₂H₁₄N₄O₇Se
SMILES

OC[C@H]1O[C@@H](O)[C@H](NC2=CC=C([N+]([O-])=O)C3=N[Se]N=C32)[C@@H](O)[C@@H]1O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Benson S, et al. SCOTfluors: Small, Conjugatable, Orthogonal, and Tunable Fluorophores for In Vivo Imaging of Cell Metabolism. Angew Chem Int Ed Engl. 2019;58(21):6911-6915. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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Biologische Aktivität
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- In Vitro
Chemical Information
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NIR‐fluorescent glucose

Alle GLUT Isoform-spezifische Produkte anzeigen