55 Results for "

Glycine (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (55)

55 Results for "Glycine (Standard)" in MCE Product Catalog:

1
Glycine (Standard)
Glycine (Standard)
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1 Cited Publications
Cat. No.: HY-Y0966R
CAS No.: 56-40-6
Category:  

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Disease markers Endogenous metabolite Cancer

Target:  

Reference Standards Endogenous Metabolite iGluR VEGFR

Glycine (Standard) is the analytical standard of Glycine. This product is intended for research and analytical applications. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis .
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N,N-Dimethylglycine (Standard)
N,N-Dimethylglycine (Standard)
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1 Cited Publications
Cat. No.: HY-Y0511R
CAS No.: 1118-68-9
Synonyms: DimethylGlycine (Standard); DMG (Standard); N-Methylsarcosine (Standard)
Category:  

Microorganisms Other disease Disease markers Amino acids Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite iGluR Amino Acid Derivatives

N,N-Dimethylglycine (Dimethylglycine) (Standard) is the analytical standard of N,N-Dimethylglycine (HY-Y0511). This product is intended for research and analytical applications. N,N-Dimethylglycine (Dimethylglycine), a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine has antidepressant-like and surfactant effects.
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L-Glutathione reduced (Standard)
L-Glutathione reduced (Standard)
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Cat. No.: HY-D0187R
CAS No.: 70-18-8
Synonyms: GSH (Standard); γ-L-Glutamyl-L-cysteinyl-Glycine (Standard)
Category:  

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS) Ferroptosis

L-Glutathione reduced (Standard) is the analytical standard of L-Glutathione reduced. This product is intended for research and analytical applications. L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.
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Glyphosate (Standard)
Glyphosate (Standard)
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Cat. No.: HY-B0863R
CAS No.: 1071-83-6
Category:  

Microorganisms

Target:  

Reference Standards Apoptosis Autophagy Necroptosis

Glyphosate (Standard) is the analytical standard of Glyphosate. This product is intended for research and analytical applications. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants .
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Cholic acid (Standard)
Cholic acid (Standard)
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Cat. No.: HY-N0324R
CAS No.: 81-25-4
Category:  

Human Gut Microbiota Metabolites Microorganisms Other disease Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Steroids

Target:  

Reference Standards Endogenous Metabolite

Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .
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L-Phenylalanine (Standard)
L-Phenylalanine (Standard)
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Cat. No.: HY-N0215R
CAS No.: 63-91-2
Synonyms: (S)-2-Amino-3-phenylpropionic acid (Standard)
Category:  

Microorganisms Animals Amino acids Endogenous metabolite

Target:  

Reference Standards Calcium Channel iGluR Endogenous Metabolite

L-Phenylalanine (Standard) is the analytical standard of L-Phenylalanine. This product is intended for research and analytical applications. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals .
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DMOG (Standard)
DMOG (Standard)
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Cat. No.: HY-15893R
CAS No.: 89464-63-1
Synonyms: Dimethyloxallyl Glycine (Standard)
Target:  

HIF/HIF Prolyl-Hydroxylase Autophagy Reference Standards

Research Areas:  

Cancer

DMOG (Standard) is the analytical standard of DMOG. This product is intended for research and analytical applications. DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo . DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal . DMOG induces cell autophagy .
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Sarcosine (Standard)
Sarcosine (Standard)
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Cat. No.: HY-101037R
CAS No.: 107-97-1
Synonyms: N-MethylGlycine (Standard); Sarcosin (Standard)
Category:  

Human Gut Microbiota Metabolites Microorganisms Immune System Disorder Disease markers Endocrine diseases Amino acids Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite GlyT

Sarcosine (Standard) is the analytical standard of Sarcosine. This product is intended for research and analytical applications. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia .
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Colchicine (Standard)
Colchicine (Standard)
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Cat. No.: HY-16569R
CAS No.: 64-86-8
Category:  

Natural Products other families Plants

Target:  

Reference Standards Microtubule/Tubulin NOD-like Receptor (NLR) Autophagy Apoptosis

Colchicine (Standard) is the analytical standard of Colchicine. This product is intended for research and analytical applications. Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research .
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Glycochenodeoxycholic acid sodium salt (Standard)
Glycochenodeoxycholic acid sodium salt (Standard)
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Cat. No.: HY-N2334AR
CAS No.: 16564-43-5
Synonyms: ChenodeoxycholylGlycine sodium salt (Standard); Sodium glycochenodeoxycholate (Standard)
Category:  

Endogenous metabolite Steroids

Target:  

Reference Standards Endogenous Metabolite Apoptosis STAT BCL6 Interleukin Related Caspase

Glycochenodeoxycholic acid sodium salt (Standard) is the analytical standard of Glycochenodeoxycholic acid sodium salt. This product is intended for research and analytical applications. Glycochenodeoxycholic acid sodium salt (Sodium glycochenodeoxycholate) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid sodium salt inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid sodium salt induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid sodium salt is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC) .
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Glycochenodeoxycholic acid (Standard)
Glycochenodeoxycholic acid (Standard)
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Cat. No.: HY-N2334R
CAS No.: 640-79-9
Synonyms: ChenodeoxycholylGlycine (Standard)
Category:  

Microorganisms Endogenous metabolite Steroids

Target:  

Reference Standards Caspase STAT Interleukin Related BCL6 Endogenous Metabolite Apoptosis

Glycochenodeoxycholic acid (Standard) is the analytical standard of Glycochenodeoxycholic acid. This product is intended for research and analytical applications. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC)[1][2][3][4].
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Glycylglycine (Standard)
Glycylglycine (Standard)
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Cat. No.: HY-D0889R
CAS No.: 556-50-3
Synonyms: Gly-Gly (Standard); H-Gly-Gly-OH (Standard)
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

Glycylglycine (Standard) is the analytical standard of Glycylglycine (HY-D0889). This product is intended for research and analytical applications. Glycylglycine is a non-selective glycylglycine dipeptidase substrate and iNOS inhibitor. Glycylglycine can cross the cell membrane by passive diffusion and is hydrolyzed to glycine in the cell, participating in energy metabolism and antioxidant processes. Glycylglycine promotes spermatogonial stem cells (SSCs) proliferation, inhibits astrocyte overactivation and reduces nitric oxide (NO) release, while upregulating the expression of neurotrophic factors (such as PDGFA, FGF2, CNTF) to support nerve myelin repair. Glycylglycine can be used to study male reproductive biology (such as SSCs proliferation regulation) and neurodegenerative diseases (such as neuroprotective mechanisms in multiple sclerosis) .
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Glycoursodeoxycholic acid (Standard)
Glycoursodeoxycholic acid (Standard)
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Cat. No.: HY-N1424R
CAS No.: 64480-66-6
Synonyms: GUDCA (Standard); UrsodeoxycholylGlycine (Standard)
Category:  

Microorganisms Endogenous metabolite Steroids

Target:  

Reference Standards Endogenous Metabolite

Glycoursodeoxycholic acid (Standard) is the analytical standard of Glycoursodeoxycholic acid. This product is intended for research and analytical applications. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.
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Glycohyodeoxycholic acid (Standard)
Glycohyodeoxycholic acid (Standard)
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Cat. No.: HY-126995R
CAS No.: 13042-33-6
Category:  

Metabolic Disease Endogenous metabolite Disease Research Fields Steroids

Target:  

Reference Standards Endogenous Metabolite

Glycohyodeoxycholic acid (Standard) is the analytical standard of Glycohyodeoxycholic acid. This product is intended for research and analytical applications. Glycohyodeoxycholic acid is a glycine-conjugated bile acid and also a metabolite of Hyodeoxycholic acid (HY-N0169). The serum level of Glycohyodeoxycholic acid is negatively correlated with the severity of non-alcoholic fatty liver disease. Glycohyodeoxycholic acid can be used in research related to non-alcoholic fatty liver disease.
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Guanidinoethyl sulfonate (Standard)
Guanidinoethyl sulfonate (Standard)
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Cat. No.: HY-113329R
CAS No.: 543-18-0
Synonyms: Taurocyamine (Standard)
Category:  

Natural Products Other disease Disease markers Endogenous metabolite

Target:  

Endogenous Metabolite Reference Standards

Guanidinoethyl sulfonate (Standard) is the analytical standard of Guanidinoethyl sulfonate. This product is intended for research and analytical applications. Guanidinoethyl sulfonate is an orally available, blood-brain permeable competitive inhibitor of taurine transporters and a competitive antagonist of glycine receptors (GlyR) (IC50=565 μM). Guanidinoethyl sulfonate has both weak agonist and antagonist effects on GABAA receptors. Guanidinoethyl sulfonate inhibits taurine transmembrane transport and competitively binds to the GlyR ligand binding domain, thereby blocking glycine-mediated chloride influx, and may regulate brain pH to exert neuroprotective effects. Guanidinoethyl sulfonate can be used for neuroprotection studies of ischemic brain injury .
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Palmitoylglycine (Standard)
Palmitoylglycine (Standard)
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Cat. No.: HY-W074890R
CAS No.: 2441-41-0
Synonyms: N-palmitoyl Glycine (Standard)
Category:  

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Reference Standards Calcium Channel NO Synthase

Palmitoylglycine (Standard) is the analytical standard of Palmitoylglycine. This product is intended for research and analytical applications. Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA[1][2][3].
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Glycolithocholic acid (Standard)
Glycolithocholic acid (Standard)
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Cat. No.: HY-116374R
CAS No.: 474-74-8
Synonyms: LithocholylGlycine (Standard)
Category:  

Human Gut Microbiota Metabolites Endogenous metabolite Steroids

Target:  

Endogenous Metabolite Reference Standards

Glycolithocholic acid (Standard) is the analytical standard of Glycolithocholic acid. This product is intended for research and analytical applications. Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .
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Indole-2-carboxylic acid (Standard)
Indole-2-carboxylic acid (Standard)
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Cat. No.: HY-I0096R
CAS No.: 1477-50-5
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Endogenous Metabolite iGluR Reference Standards

Indole-2-carboxylic acid (Standard) is the analytical standard of Indole-2-carboxylic acid. This product is intended for research and analytical applications. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current .
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3-Hydroxyhippuric acid (Standard)
3-Hydroxyhippuric acid (Standard)
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Cat. No.: HY-113085R
CAS No.: 1637-75-8
Category:  

Monophenols Ketones, Aldehydes, Acids Phenols Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

3-Hydroxyhippuric acid (Standard) is the analytical standard of 3-Hydroxyhippuric acid. This product is intended for research and analytical applications. 3-Hydroxyhippuric acid is an acyl glycine. 3-Hydroxyhippuric acid inhibits kynureninase (Ki = 60 μM). 3-Hydroxyhippuric acid is found in higher concentrations in autistic group than in the controls. 3-Hydroxyhippuric acid is a marker of Clostridium species, and has a positive correlation with the level of Clostridia. 3-Hydroxyhippuric acid is one of the main metabolites formed from the catechin diet and wine polyphenol diets .
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Thiocolchicoside (Standard)
Thiocolchicoside (Standard)
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Cat. No.: HY-N0301R
CAS No.: 602-41-5
Target:  

Reference Standards GABA Receptor

Research Areas:  

Neurological Disease Inflammation/Immunology

Thiocolchicoside (Standard) is the analytical standard of Thiocolchicoside. This product is intended for research and analytical applications. Thiocolchicoside is a competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties .
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