16 Results for "

HeLa cell line

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "HeLa cell line" in MCE Product Catalog:

33
33 Cited Publications
Cat. No.: HY-12033
CAS No.: 362-07-2
Purity:  99.76%
Synonyms: 2-ME2; NSC-659853
2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .
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Cat. No.: HY-12033S2
CAS No.: 358731-34-7
Purity:  98.67%
Synonyms: 2-ME2-d5; NSC-659853-d5
2-Methoxyestradiol-d5 is the deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .
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Cat. No.: HY-122751
CAS No.: 1630760-60-9
Purity:  99.59%
Research Areas:  

Cancer

(R)-DNMDP is a potent and selective cancer cell cytotoxic agent. (R)-DNMDP, the R-form of DNMDP, binds PDE3A directly. (R)-DNMDP has a 500-fold lower EC50 compared to the (S)-enantiomer in HeLa cell line .
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Cat. No.: HY-D2817
Target:  

Fluorescent Dye

Research Areas:  

Others

FITC-PLL is a fluorescently labeled polycationic polypeptide probe composed of polylysine (PLL) and FITC (HY-66019), with a typical Ex/Em of 495/520 nm. The fluorescence intensity and lifetime of FITC-PLL are sensitive to pH and FITC density. FITC-PLL can be used for quantifying hapten receptor binding and endocytosis kinetics in macrophages, as a patternable substrate for neuron guidance, for negatively charged phospholipid membrane binding and transmembrane transport, and for live-cell imaging of starch nanoparticle conjugates and lysosome labeling .
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Cat. No.: HY-12033S1
Synonyms: 2-ME2-13C6; NSC-659853-13C6
2-Methoxyestradiol- 13C6 is the 13C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .
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Cat. No.: HY-12033S
CAS No.: 1217470-09-1
2-Methoxyestradiol- 13C,d3 is the 13C- and deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .
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Cat. No.: HY-158058
CAS No.: 3029403-05-9
WYJ-2 is a selective agonist for toll-like receptor 2/1 (TLR2/1) with EC50 of 18.57 nM in human TLR2 and TLR1 transient-cotransfected HEK 293T cells. WYJ-2 induces pyroptosis and exhibits anticancer activity against non-small cell lung cancer (NSCLC) .
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Cat. No.: HY-116621
CAS No.: 503468-03-9
Target:  

DNA-PK

Research Areas:  

Cancer

NU-7163 is an ATP-competitive DNA-PK inhibitor (IC50=0.19 μM; Ki=24 nM). NU-7163 enhances the cytotoxicity of ionizing radiation against the HeLa human tumor cell line in vitro .
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Cat. No.: HY-N2213
CAS No.: 106647-14-7
Matairesinol 4′-O-β-D-glucopyranoside displays cytotoxic activity against HeLa cell line with an IC50 of 47.1 μM .
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Cat. No.: HY-161076
CAS No.: 2244987-60-6
Research Areas:  

Cancer

KTt-45 is a T-type calcium channel blocker. KTt-45 has anticancer effect by inducing apoptosis on HeLa cervical cancer cell line .
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Cat. No.: HY-N8230
CAS No.: 2231756-23-1
Ganosinensic acid C is a triterpenoid compound that can be extracted from Ganoderma lucidum. Ganosinensic acid C has important biological activities such as anti-tumor, anti-prostate cancer, anti-inflammatory, and inhibition of HIV-I protease. Ganosinensic acid C has an IC50 value of 10.5 μM against human highly metastatic lung cancer cell line 95D. Ganosinensic acid C has an IC50 value of Ganosinensic acid C against cervical cancer cell line Hela is 13.2 μM .
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Cat. No.: HY-160691
CAS No.: 886599-05-9
Target:  

Aurora Kinase

Research Areas:  

Others

GW814408X is a kinase chemical genome group (KCGS) compound that inhibits the AURKC kinase involved in cell cycle progression, checkpoint regulation, and cell division. GW814408X exhibits cell line-dependent toxicity, e.g., cytotoxic effects on HeLa cells. GW814408X acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays .
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Cat. No.: HY-12033R
CAS No.: 362-07-2
Synonyms: 2-ME2 (Standard); NSC-659853 (Standard)
2-Methoxyestradiol (Standard) is the analytical standard of 2-Methoxyestradiol. This product is intended for research and analytical applications. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .
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Cat. No.: HY-D3163
Target:  

Fluorescent Dye

Research Areas:  

Others

Endo-pH is a cell-permeable, pH-responsive fluorescent probe based on BODIPY, with a pKa of 5.08. When pH decreases from 7.32 to 4.97, Endo-pH undergoes protonation under acidic conditions, resulting in a 79-fold increase in fluorescence intensity at 786 nm. The detection wavelengths of its protonated form are Ex/Em=688/786 nm, while the absorption wavelength of its non-protonated form is 745 nm. Endo-pH can be used for staining late endosomes in live cells and determining the fusion time of late endosomes and lysosomes .
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Cat. No.: HY-N21770
CAS No.: 303088-44-0
Densiflorol A is a bibenzyl compound and anticancer agent. Densiflorol A can be isolated from Bulbophyllum kwangtungense. Densiflorol A exhibits antitumor activity against leukemia and cervical cancer .
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Cat. No.: HY-N21628
CAS No.: 1011528-66-7
Phanginin I is a cassane-type furanoditerpene found in the seeds of Caesalpinia sappan. Phanginin I exhibits cytotoxicity against KB, HL-60, and HeLa cancer cells. Phanginin I can be used in research related to tumor cytotoxicity .
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