3029403-05-9
3029403-05-9
Chemical Structure
WYJ-2
- CAS No.: 3029403-05-9
- Formula:C17H9F2N3O4
- Molecular Weight:357.27
InChIKey: WVIOJTZQQHDPIZ-UHFFFAOYSA-N
SMILES: FC1=CC=C(C=C1C2=NC(C3=CC4=CC(F)=CC=C4OC3)=NO2)[N+]([O-])=O
Biological Activity: WYJ-2 is a selective agonist for toll-like receptor 2/1 (TLR2/1) with EC50 of 18.57 nM in human TLR2 and TLR1 transient-cotransfected HEK 293T cells. WYJ-2 induces pyroptosis and exhibits anticancer activity against non-small cell lung cancer (NSCLC)[1].
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WYJ-2 | WYJ-2 is a selective agonist for toll-like receptor 2/1 (TLR2/1) with EC50 of 18.57 nM in human TLR2 and TLR1 transient-cotransfected HEK 293T cells. WYJ-2 induces pyroptosis and exhibits anticancer activity against non-small cell lung cancer (NSCLC). | |||||||||||||||||||||
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References
Keywords
