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Hormone regulation

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48

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3

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1

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3

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14

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1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W250978
    Ovalbumins
    4 Publications Verification

    		 Endogenous Metabolite Cardiovascular Disease Infection Inflammation/Immunology Cancer
    Ovalbumins (OVA), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues .
    We recommend using Ovalbumin, low endotoxin (HY-W250978A) to establish an asthma model.
    Ovalbumins
  • HY-B1033
    Metergoline
    2 Publications Verification

    		 5-HT Receptor Dopamine Receptor Sodium Channel Neurological Disease
    Metergoline is a serotonin (5-HT) receptor and dopamine receptors antagonist, with pKis of 8.64, 8.75 and 8.75 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. Metergoline is a high-affinity ligand for the h5-HT7 receptor, with a Ki of 16 nM. Metergoline is also a reversible neural Na + channels inhibitor. Metergoline is commonly used for the research of seasonal affective disorder, prolactin hormone regulation .
    Metergoline
  • HY-N2549
    (±)-Abscisic acid

    (±)-ABA

    		 Calcium Channel Metabolic Disease Inflammation/Immunology
    (±)-Abscisic acid is an orally active plant hormone that is present also in animals. (±)-Abscisic acid (ABA) contributes to the regulation of glycemia in mammals .
    (±)-Abscisic acid
  • HY-N12634
    Pregnant mare serum gonadotropin

    PMSG

    		 Endogenous Metabolite Endocrinology
    Pregnant mare serum gonadotropin (PMSG) is a gonadotropin used to promote follicular development and ovulation in animals. PMSG exerts its regulatory effects by stimulating changes in blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. PMSG is commonly used in livestock to improve reproductive efficiency and can also be utilized for research on estrous cycle regulation .
    Pregnant mare serum gonadotropin
  • HY-P991202
    Anti-TSHR Antibody (M22)

    		TSH Receptor PKA Metabolic Disease Inflammation/Immunology
    Anti-TSHR Antibody (M22) is a selective agonist targeting TSHR (thyroid-stimulating hormone receptor), acting through competitive binding to the extracellular domain of TSHR. Anti-TSHR Antibody (M22) can mimic the biological effects of thyroid-stimulating hormone (TSH), activating downstream cAMP-PKA and other signaling pathways. Anti-TSHR Antibody (M22) can stimulate the proliferation of thyroid follicular epithelial cells and human umbilical vein endothelial cells (HUVECs), promote angiogenesis and tube formation, cell migration, and also upregulate the expression of angiogenesis-related proteins such as PROX1. Anti-TSHR Antibody (M22) can be used in research areas such as the mechanisms of goiter formation in Graves' disease (GD), angiogenesis regulation, and TSHR antagonist screening .
    Anti-TSHR Antibody (M22)
  • HY-W250978A
    Ovalbumin, low endotoxin

    		Biochemical Assay Reagents Inflammation/Immunology
    Ovalbumin, low endotoxin (OVA, low endotoxin), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues . Ovalbumin, a low endotoxin, can be used to establish an asthma model .
    Ovalbumin, low endotoxin
  • HY-107916
    Thyrotropin
    1 Publications Verification

    TSH; Pretiron

    		 TSH Receptor PKC Apoptosis Metabolic Disease Inflammation/Immunology Endocrinology Cancer
    Thyrotropin (TSH, Pretiron) is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid. Thyrotropin induces transcriptional regulation of TH-gatekeeper genes in tanycytes through the Tshr/Gαq/PKC pathway. Thyrotropin prevents Apoptosis. Thyrotropin has an association of low levels with increased bone remodeling, reduced bone mass and a high fracture risk in mice. Thyrotropin is promising for research of skeletal remodeling, hyperthyroidism .
    Thyrotropin
  • HY-Y0079
    D-Phenylalanine

    		Endogenous Metabolite Infection
    D-Phenylalanine is an atypical D-amino acid and an inhibitor of bacterial biofilm formation. D-Phenylalanine mainly replaces D-alanine (D-Ala) by incorporating into the fourth and fifth positions of bacterial peptidoglycan (PG), changing the cell wall structure, enhancing bacterial acid resistance and affecting biofilm formation. D-Phenylalanine may promote the secretion of peptide tyrosine tyrosine (PYY) in mammals by activating the intestinal GPR109B receptor. D-Phenylalanine can inhibit the maturation of microbial biofilms and promote the release of specific hormones. It can be used for antibacterial preservation, improving the yield of probiotics in the food industry, and studying appetite regulation and blood sugar control in metabolic diseases such as diabetes .
    D-Phenylalanine
  • HY-P0097
    Nonapeptide-1
    2 Publications Verification

    Melanostatine-5

    		 Melanocortin Receptor Metabolic Disease Endocrinology Cancer
    Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R (Ki: 40 nM). Nonapeptide-1 is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC50: 2.5 nM and 11 nM, respectively). Nonapeptide-1 inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer .
    Nonapeptide-1
  • HY-N0179
    Ecdysone
    1 Publications Verification

    α-Ecdysone

    		 Endogenous Metabolite Apoptosis Metabolic Disease
    Ecdysone (α-Ecdysone), a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979) .
    Ecdysone
  • HY-42068
    (-)-Aspartic acid

    (R)-Aspartic acid; D-(-)-Aspartic acid

    		 Pyroptosis Neurological Disease
    (-)-Aspartic acid is a pyroptosis inhibitor. (-)-Aspartic acid acts as a neurotransmitter and neuromodulator, participates in hormone synthesis and regulation, and plays a role in nervous system development and endocrine system .
    (-)-Aspartic acid
  • HY-125209
    TH5427

    		DNA/RNA Synthesis Cancer
    TH5427 is a promising, targeted inhibitor that can be used to further study NUDT5 activity and ADP-ribose metabolism. TH5427, blocks progestin-dependent, PAR-derived nuclear ATP synthesis and subsequent chromatin remodeling, gene regulation and proliferation in breast cancer cells. NUDT5 is recently identified as a rheostat of hormone-dependent gene regulation and proliferation in breast cancer cells .
    TH5427
  • HY-P4373A
    Hepcidin-1 (mouse) TFA
    1 Publications Verification

    		 Cathepsin MMP Inflammation/Immunology
    Hepcidin-1 (mouse) TFA is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) TFA upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) TFA downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) TFA facilitates osteoclast differentiation .
    Hepcidin-1 (mouse) TFA
  • HY-P2426
    (D-Trp12,Tyr34)-pTH (7-34) amide (bovine)

    		Thyroid Hormone Receptor Metabolic Disease
    (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation .
    (D-Trp12,Tyr34)-pTH (7-34) amide (bovine)
  • HY-130012
    CO23
    1 Publications Verification

    		 Thyroid Hormone Receptor Metabolic Disease
    CO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation .
    CO23
  • HY-B1012
    Quinestrol

    W-3566

    		 Estrogen Receptor/ERR Cytochrome P450 GnRH Receptor Metabolic Disease Endocrinology
    Quinestrol (W-3566) is an orally effective synthetic estrogen compound that acts on CYP3A4, CYP1A2, and GnRH. Quinestrol interferes with GnRH release and disrupts the hypothalamic-pituitary-ovarian axis. Quinestrol downregulates the gene expression of follicle-stimulating hormone β and luteinizing hormone β, induces oxidative stress, damages reproductive organs, reduces sperm density and motility, increases sperm malformation rate, and alters the levels of sex hormones such as testosterone, luteinizing hormone, estradiol, and progesterone. Quinestrol can be used in studies related to reproductive function regulation .
    Quinestrol
  • HY-122940
    Precocene II

    Ageratochromene

    		 Endogenous Metabolite Metabolic Disease
    Precocene II (Ageratochromene) is a plant larva hormone antagonists that inhibits the biosynthesis of juvenile hormone. Precocene II inhibits corpora allata function and downregulates juvenile hormone levels, while exerting multiple effects including inducing precocious metamorphosis, forming macropterous morphs, inhibiting ovarian growth, producing cytotoxicity, disrupting insect development, and causing sterility and kidney damage. Precocene II blocks normal nymphal development, causes renal tubular damage and increases blood urea nitrogen levels, and also blocks juvenile hormone biosynthesis in vitro. Precocene II undergoes oxidative metabolism catalyzed by NADPH-dependent monooxygenase to generate a variety of metabolites. Precocene II can be applied in studies related to insect growth regulation and nephrotoxicity .
    Precocene II
  • HY-15157
    Calcitetrol

    1α, 24, 25-Trihydroxy VD3

    		 VD/VDR Drug Metabolite Infection
    Calcitetrol (1α, 24, 25-Trihydroxy VD3), a Vitamin D3 (HY-15398) metabolite, is the hormonally active form of vitamin D. Calcitetrol participates in regulation of Treg cells. Calcitetrol can be used for the research of Toxoplasma gondii infection .
    Calcitetrol
  • HY-16785
    Veledimex

    INXN-1001; RG-115932

    		 Interleukin Related Inflammation/Immunology Cancer
    Veledimex (INXN-1001), a synthetic analog of the insect molting hormone ecdysone, is an orally active activator ligand for a proprietary gene therapy promoter system. Veledimex can be used to activate certain genes using the ecdysone receptor (EcR)-based inducible gene regulation system, the RheoSwitch Therapeutic System (RTS). Veledimex can cross blood-brain barrier (BBB) in both orthotopic GL-261 mice and cynomolgus monkeys .
    Veledimex
  • HY-P0097A
    Nonapeptide-1 acetate salt
    2 Publications Verification

    Melanostatine-5 acetate salt

    		 Melanocortin Receptor Metabolic Disease Endocrinology Cancer
    Nonapeptide-1 (Melanostatine-5) acetate salt, a peptide hormone, is a selective antagonist of MC1R (Ki: 40 nM). Nonapeptide-1 acetate salt is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC50: 2.5 nM and 11 nM, respectively). Nonapeptide-1 acetate salt inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer .
    Nonapeptide-1 acetate salt
  • HY-107648
    McN-A-343
    2 Publications Verification

    		 mAChR Neurological Disease Inflammation/Immunology
    McN-A-343 is a selective M1 muscarinic agonist that stimulates muscarinic transmission in sympathetic ganglia. McN-A-343 produces a significant inhibitory effect on Muscarine (HY-121404)-evoked catecholamine secretion from the isolated perfused rat adrenal gland. McN-A-343 is involved in the regulation of neuronal firing and activates enteroendocrine L cells to release glucagon-like peptide 1 (GLP-1) and modulates the secretion of α-melanocyte stimulating hormone (α-MSH) from the pituitary gland in the central nervous system. McN-A-343 reduces colonic inflammation and oxidative stress in Acetic acid (HY-Y0319)-induced ulcerative colitis (UC) mice. McN-A-343 can be used for the study of ulcerative colitis .
    McN-A-343
  • HY-W588263
    Indole-3-acetyl glutamate

    IAGlu

    		 Drug Derivative Others
    Indole-3-acetyl glutamate (IAGlu) is a derivative of the plant hormone indole-3-acetic acid (IAA). As a conjugated form of IAA, Indole-3-acetyl glutamate involves in the transport, storage, and homeostatic regulation of IAA within the plant. Indole-3-acetyl glutamate can be used for research into the effects of plant hormones on the growth and development of plants .
    Indole-3-acetyl glutamate
  • HY-P1373
    Neuronostatin-13 (human)
    1 Publications Verification

    		 Somatostatin Receptor Neurological Disease
    Neuronostatin-13 human is a 13-amino acid peptide hormone encoded by the somatostatin gene and plays an important role in the regulation of hormonal and cardiac function.
    Neuronostatin-13 (human)
  • HY-P10419
    Zebrafish Kisspeptin-1

    		Kisspeptin Receptor GnRH Receptor Endocrinology
    Zebrafish Kisspeptin-1 is the core sequence of the neuropeptide kisspeptin-1, which participate in the regulation of gonadotropin-releasing hormone (GnRH) release, and regulates the reproductive system .
    Zebrafish Kisspeptin-1
  • HY-P5792
    Atrial natriuretic peptide (3-28) (human)

    ANP (3-28) (human)

    		 Endothelin Receptor Cardiovascular Disease Metabolic Disease
    Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)) is a peptide hormone that is synthesized and secreted by the atrial myocardium. Atrial natriuretic peptide (3-28) (human) is involved in the regulation of blood pressure, fluid balance, and electrolyte homeostasis .
    Atrial natriuretic peptide (3-28) (human)
  • HY-P4373
    Hepcidin-1 (mouse)

    		Cathepsin MMP Metabolic Disease
    Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) facilitates osteoclast differentiation .
    Hepcidin-1 (mouse)
  • HY-P1245
    Neuropeptide SF (human)

    Neuropeptide NPFF (human)

    		 CRFR Others
    Neuropeptide SF human augments paraventricular corticotrophin-releasing hormone (CRH) release and increases adrenocorticotropic hormone (ACTH) and corticosterone levels in the plasma. Neuropeptide SF human play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH .
    Neuropeptide SF (human)
  • HY-N13014
    Indole-3-acetyl β-D-glucopyranose

    		Others Others
    Indole-3-acetyl β-D-glucopyranose is a glucose esterified derivative of the plant hormone indole-3-acetic acid (IAA). Indole-3-acetyl β-D-glucopyranose is involved in regulating plant growth and can be used to study the metabolism and regulatory mechanisms of plant hormones .
    Indole-3-acetyl β-D-glucopyranose
  • HY-P4849
    pTH-Related Protein (1-37) (human, mouse, rat)

    		PTHR Others
    pTH-Related Protein (1-37) (human, mouse, rat), the peptide analogue of pTH-Related Protein (pTHrP). pTHrP refers to parathyroid-hormone-related protein, involved in physiological regulation of bone formation .
    pTH-Related Protein (1-37) (human, mouse, rat)
  • HY-N10511
    GM1a Ganglioside oligosaccharide

    		Others Inflammation/Immunology
    GM1a Ganglioside oligosaccharide is a semisynthetic form of ganglioside GM1. Ganglioside GM1 is the natural receptor for cholera toxin and plays an important role not only in general growth regulation but also in the coupling of hormone-induced responses .
    GM1a Ganglioside oligosaccharide
  • HY-176729
    KeIKK5

    		Phytohormone Others
    KeIKK5 is a strigolactone (SL) biosynthesis inhibitor. KeIKK5 significantly reduces the level of 4-deoxystrigolactone (4-DO) in rice by inhibiting the activity of CYP711A enzyme. KeIKK5 can effectively inhibit the germination of root parasitic weeds. KeIKK5 can be used in the research of plant hormone regulation and new agricultural herbicides .
    KeIKK5
  • HY-B1033R
    Metergoline (Standard)

    		5-HT Receptor Dopamine Receptor Sodium Channel Reference Standards Neurological Disease
    Metergoline (Standard) is the analytical standard of Metergoline. This product is intended for research and analytical applications. Metergoline is a serotonin (5-HT) receptor and dopamine receptors antagonist, with pKis of 8.64, 8.75 and 8.75 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. Metergoline is a high-affinity ligand for the h5-HT7 receptor, with a Ki of 16 nM. Metergoline is also a reversible neural Na+ channels inhibitor. Metergoline is commonly used for the research of seasonal affective disorder, prolactin hormone regulation .
    Metergoline (Standard)
  • HY-P2419
    [Ala6]-LHRH

    		GnRH Receptor Endocrinology
    [Ala6]-LHRH is a synthetic luteinizing hormone-releasing hormone agonist, demonstrating effective stimulation of pituitary luteinizing hormone secretion. [Ala6]-LHRH enhances reproductive hormone regulation, contributing to fertility treatments. [Ala6]-LHRH plays a crucial role in managing conditions related to hormone imbalances.
    [Ala6]-LHRH
  • HY-P1463
    Calcitonin, eel

    Thyrocalcitonin eel

    		 Thyroid Hormone Receptor Endocrinology
    Calcitonin, eel is the thyroid hormone peptide that contributes to the regulation of calcium homeostasis, widely used in the research of postmenopausal osteoporosis.
    Calcitonin, eel
  • HY-P1463A
    Calcitonin, eel TFA

    Thyrocalcitonin eel TFA

    		 Thyroid Hormone Receptor Others
    Calcitonin, eel TFA is the thyroid hormone peptide that contributes to the regulation of calcium homeostasis, widely used in the research of postmenopausal osteoporosis .
    Calcitonin, eel TFA
  • HY-163784
    AKR1C3-IN-14

    		Aldose Reductase Cancer
    AKR1C3-IN-14 (compound 4) is an AKR1C3 inhibitor (IC50=0.122 μM) that reduces the overproduction of androgens by inhibiting the activity of the AKR1C3 enzyme, thereby regulating hormone-mediated signaling. AKR1C3-IN-14 also plays a role in the biosynthesis of the prostaglandin PGF2α, regulating cell proliferation by affecting this pathway. AKR1C3-IN-14 can be used in the study of prostate cancer .
    AKR1C3-IN-14
  • HY-P1245A
    Neuropeptide SF (human) acetate

    Neuropeptide NPFF (human) acetate

    		 CRFR Others
    Neuropeptide SF (human) acetate augments paraventricular corticotrophin-releasing hormone (CRH) release and increases adrenocorticotropic hormone (ACTH) and corticosterone levels in the plasma. Neuropeptide SF (human) acetate play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH .
    Neuropeptide SF (human) acetate
  • HY-42068R
    (-)-Aspartic acid (Standard)

    (R)-Aspartic acid (Standard); D-(-)-Aspartic acid (Standard)

    		 Reference Standards Pyroptosis Neurological Disease
    (-)-Aspartic acid (Standard) is the analytical standard of (-)-Aspartic acid. This product is intended for research and analytical applications. (-)-Aspartic acid is a pyroptosis inhibitor. (-)-Aspartic acid acts as a neurotransmitter and neuromodulator, participates in hormone synthesis and regulation, and plays a role in nervous system development and endocrine system .
    (-)-Aspartic acid (Standard)
  • HY-W874850
    Fluorodifen

    		Herbicide
    Fluorodifen is a selective herbicide with the activity of inhibiting weed growth. Fluorodifen can effectively control the growth of various annual and perennial broadleaf weeds and some grass weeds, and is widely used in the field management of various crops. By acting on the photosynthesis of plants and the regulation of their growth hormones, Fluorodifen ensures the healthy growth and harvest of crops.
    Fluorodifen
  • HY-W588263S1
    Indole-3-acetyl glutamate-d4

    IAGlu-d4

    		 Isotope-Labeled Compounds Others Others
    Indole-3-acetyl glutamate-d4 (IAGlu-d4) is deuterium labeled Indole-3-acetyl glutamate. Indole-3-acetyl glutamate (IAGlu) is a derivative of the plant hormone indole-3-acetic acid (IAA). As a conjugated form of IAA, Indole-3-acetyl glutamate involves in the transport, storage, and homeostatic regulation of IAA within the plant. Indole-3-acetyl glutamate can be used for research into the effects of plant hormones on the growth and development of plants .
    Indole-3-acetyl glutamate-d4
  • HY-W698686
    β-Galactosyl-C18-ceramide

    		Biochemical Assay Reagents
    β-Galactosyl-C18-ceramide is a bioactive molecule that promotes the regulation of nerve cells, regulates protein kinase C activity, and affects hormone receptors. β-Galactosyl-C18-ceramide is widely used in neuroscience research to explore its effects on nerve cell growth and function. The regulatory function of β-Galactosyl-C18-ceramide makes it a potential application prospect in compound development and disease inhibition.
    β-Galactosyl-C18-ceramide
  • HY-W698686S
    β-Galactosyl-C18-ceramide-d35

    		Isotope-Labeled Compounds Others Others
    β-Galactosyl-C18-ceramide-d35 is deuterium labeled β-Galactosyl-C18-ceramide. β-Galactosyl-C18-ceramide is a bioactive molecule that promotes the regulation of nerve cells, regulates protein kinase C activity, and affects hormone receptors. β-Galactosyl-C18-ceramide is widely used in neuroscience research to explore its effects on nerve cell growth and function. The regulatory function of β-Galactosyl-C18-ceramide makes it a potential application prospect in compound development and disease inhibition .
    β-Galactosyl-C18-ceramide-d35
  • HY-W738639
    18-Hydroxy-11-deoxy corticosterone

    18-OH-DOC; 11-Deoxy-18-hydroxycorticosterone

    		 Melanocortin Receptor Angiotensin Receptor Drug Metabolite Mineralocorticoid Receptor Cardiovascular Disease Metabolic Disease
    18-Hydroxy-11-deoxy corticosterone (18-OH-DOC) is a mineralocorticoid whose synthesis is regulated by adrenocorticotropic hormone (ACTH) and angiotensin II. 18-Hydroxy-11-deoxy corticosterone is an intermediate in the metabolism of progesterone and plays an important role in regulating blood pressure and water-salt balance. Continuous infusion of 18-Hydroxy-11-deoxy corticosterone can increase systolic blood pressure in rats, and plasma levels of 18-Hydroxy-11-deoxy corticosterone are significantly elevated in the db/db mouse model of type 2 diabetes, suggesting its potential involvement in metabolic dysregulation and diabetes-related regulation. 18-Hydroxy-11-deoxy corticosterone holds promise for research in areas such as hypertension, diabetes, and other related fields .
    18-Hydroxy-11-deoxy corticosterone
  • HY-B1012R
    Quinestrol (Standard)

    W-3566 (Standard)

    		 Reference Standards Estrogen Receptor/ERR Metabolic Disease Endocrinology
    Quinestrol (Standard) is the analytical standard of Quinestrol (HY-B1012). This product is intended for research and analytical applications. Quinestrol (W-3566) is an orally effective synthetic estrogen compound that acts on CYP3A4, CYP1A2, and GnRH. Quinestrol interferes with GnRH release and disrupts the hypothalamic-pituitary-ovarian axis. Quinestrol downregulates the gene expression of follicle-stimulating hormone β and luteinizing hormone β, induces oxidative stress, damages reproductive organs, reduces sperm density and motility, increases sperm malformation rate, and alters the levels of sex hormones such as testosterone, luteinizing hormone, estradiol, and progesterone. Quinestrol can be used in studies related to reproductive function regulation .
    Quinestrol (Standard)
  • HY-W747928
    (-)-Aspartic acid-d3

    (R)-Aspartic acid-d3; D-(-)-Aspartic acid-d3

    		 Isotope-Labeled Compounds Pyroptosis Others
    (-)-Aspartic acid-d3 ((R)-Aspartic acid-d3) is the deuterium labeled (-)-Aspartic acid (HY-42068). (-)-Aspartic acid is a pyroptosis inhibitor. (-)-Aspartic acid acts as a neurotransmitter and neuromodulator, participates in hormone synthesis and regulation, and plays a role in nervous system development and endocrine system.
    (-)-Aspartic acid-d3
  • HY-122940R
    Precocene II (Standard)

    Ageratochromene (Standard)

    		 Others Reference Standards Metabolic Disease
    Precocene II (Standard) is the analytical standard of Precocene II (HY-122940). This product is intended for research and analytical applications. Precocene II (Ageratochromene) is a plant larva hormone antagonists that inhibits the biosynthesis of juvenile hormone. Precocene II inhibits corpora allata function and downregulates juvenile hormone levels, while exerting multiple effects including inducing precocious metamorphosis, forming macropterous morphs, inhibiting ovarian growth, producing cytotoxicity, disrupting insect development, and causing sterility and kidney damage. Precocene II blocks normal nymphal development, causes renal tubular damage and increases blood urea nitrogen levels, and also blocks juvenile hormone biosynthesis in vitro. Precocene II undergoes oxidative metabolism catalyzed by NADPH-dependent monooxygenase to generate a variety of metabolites. Precocene II can be applied in studies related to insect growth regulation and nephrotoxicity .
    Precocene II (Standard)
  • HY-W874850R
    Fluorodifen (Standard)

    		Endogenous Metabolite Reference Standards
    Fluorodifen (Standard) is the analytical standard of Fluorodifen. This product is intended for research and analytical applications. Fluorodifen is a selective herbicide with the activity of inhibiting weed growth. Fluorodifen can effectively control the growth of various annual and perennial broadleaf weeds and some grass weeds, and is widely used in the field management of various crops. By acting on the photosynthesis of plants and the regulation of their growth hormones, Fluorodifen ensures the healthy growth and harvest of crops.
    Fluorodifen (Standard)
  • HY-D2428
    OVA-PEG-Cy3

    		Fluorescent Dye Cardiovascular Disease Infection Inflammation/Immunology Cancer
    OVA-PEG-Cy3 is a Cy3 (HY-D0822)-labeled OVA-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Ovalbumins (OVA), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues .
    OVA-PEG-Cy3

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