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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

IL-10 Antibody

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Interleukin Related (11) Apoptosis (1) CD3 (1) CXCR (1) Fungal (1) IFNAR (1) JNK (1) MHC (1) NF-κB (1) p38 MAPK (1) Parasite (1) TNF Receptor (2)
By Research Areas:	Cancer (3) Infection (2) Inflammation/Immunology (9) Metabolic Disease (2) Neurological Disease (1)

Inhibitors & Agonists

Inhibitory Antibodies

Antibodies

Targets Recommended: ADC Antibody Interleukin Related IRAK Antibody-Drug Conjugates (ADCs) Antibody-Oligonucleotide Conjugates (AOCs) ADC Linker Itk PROTAC-Linker Conjugates for PAC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990228

*Anti-Mouse IL-10R/CD210 Antibody* (1B1.3A)**	Interleukin Related Parasite Fungal	Infection Metabolic Disease
Anti-Mouse IL-10R/CD210 Antibody (1B1.3A) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse *IL-10R/CD210. Anti-Mouse IL-10R/CD210* Antibody (1B1.3A) blocks IL-10R signaling. Anti-Mouse IL-10R/CD210 Antibody (1B1.3A) can be used for the researches of cancer, infection and metabolic disease, such as diabetes and malaria .

HY-P990001

Anti-Mouse IL-10 Antibody (JES5-2A5) 1 Publications Verification	Interleukin Related	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse IL-10 Antibody (JES5-2A5) is an anti-mouse *IL-10* IgG1 monoclonal antibody. Anti-Mouse IL-10 Antibody (JES5-2A5) restores the anti-tumor activity of IL-6 by blocking the IL-10/SOCS3 axis. Anti-Mouse IL-10 Antibody (JES5-2A5) can reverse microcirculation and cognitive deficits. Anti-Mouse IL-10 Antibody (JES5-2A5) can be used for researches on cancer and metabolic disease such as osteosarcoma and type 1 diabetes mellitus (T1DM) .

HY-P991400

GSK1995057	TNF Receptor Apoptosis Interleukin Related NF-κB JNK p38 MAPK	Inflammation/Immunology
GSK1995057 is a human monoclonal antibody (mAb) targeting TNFRSF1A. GSK1995057 selectively binds to TNFR1, blocks the binding of TNF-α and LT-α, and does not interfere with TNFR2 signaling. GSK1995057 inhibits the activation of NF-κB, JNK and MAPK pathways, alleviates apoptosis (apoptosis) and inflammatory responses (inhibiting IL-1β, IL-6, *IL-10, TNF-α), and prevents viability loss of human nucleus pulposus cells. GSK1995057 inhibits the expression of cytokines and neutrophil adhesion molecules in human pulmonary microvascular endothelial cell monolayers, and reduces inflammatory responses and lung injury symptoms in non-human primates. GSK1995057 forms complexes with HAVH autoantibodies, thereby activating TNFR1* and triggering the release of cytokines and IL-8 in human cells. GSK1995057 can be used in research related to intervertebral disc degeneration and acute lung injury .

HY-P99390

Tepoditamab MCLA 117	CD3 Interleukin Related IFNAR TNF Receptor	Inflammation/Immunology Cancer
Tepoditamab (MCLA-117) is a full-length human IgG1 bispecific monoclonal antibody that binds to CLEC12A of myeloid cells and CD3 of cytotoxic T cells. Among others, CLEC12A is a myeloid differentiation antigen. Tepoditamab kills AML leukaemia mother cells and AML leukaemia stem cells, induces T cell-mediated proliferative lysis of AML cells. Tepoditamab induces upto 30-fold T-cell expansion. Tepoditamab results in moderate to strong cytokine (IFNγ, IL-6, IL-8, IL-10, and TNFα) and IFNγ release in human whole blood and PBMC, respectively. Tepoditamab can be used in acute myeloid leukaemia (AML) research .

HY-P991257

MK-1966 1 Publications Verification	Interleukin Related CXCR MHC	Cancer
MK-1966 is an anti-IL-10 antibody. MK-1966 inhibits secretion of cytokines from activated macrophages, production of CC and CXC chemokines, and a TH1 response, down-regulates MHC and costimulatory molecules on dendritic cells (DCs), and induces regulatory T cells. MK-1966 can be used for the research of cancer , such as gastric cancer .

HY-P990561

BT-063	Interleukin Related	Inflammation/Immunology
BT-063 is a humanized antibody expressed in CHO cells, targeting *IL-10*. BT-063 contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145.74 kDa. The isotype control for BT-063 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P991659

SCH708980	Interleukin Related	Infection Inflammation/Immunology
SCH708980 is a humanized monoclonal antibody inhibitor targeting *IL-10*. SCH708980 has anti-immunosuppressive activity. SCH708980 can be used for visceral leishmaniasis, sepsis-associated kidney injury (SAKI) and osteoporosis research .

HY-P991760

*Anti-IL-10* Antibody (JES3-19F1)**	Interleukin Related	Inflammation/Immunology
Anti-IL-10 Antibody (JES3-19F1) reacts with human IL-10, and is a capture or coating antibody in ELISA applications. Anti-IL-10 Antibody (JES3-19F1) reduces bacterial load in Mycobacterium avium infected mice. Recommend Isotype Controls: Rat IgG2a kappa, Isotype Control (HY-P990679) .

HY-P992038

Anti-IL-10RB Antibody	Interleukin Related	Inflammation/Immunology
Anti-IL-10RB Antibody is an anti-IL-10RB antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992037

Anti-IL-10Rα Antibody	Interleukin Related	Inflammation/Immunology
Anti-IL-10Rα Antibody is an anti-IL-10Rα antibody. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).

HY-P992153

Serrumab	Interleukin Related	Inflammation/Immunology
Serrumab is a human monoclonal antibody that counteracts the biochemical and immunological effects of Tityus serrulatus venom. Serrumab inhibits the TsV-induced increase in the production of IL-6, TNFα and *IL-10*. Serrumab also prevents TsV-induced elevations in plasma urea, creatinine, aspartate transaminase and glucose levels, as well as the TsV-induced increase in neutrophil recruitment. Serrumab can be used in research related to envenoming by the Brazilian yellow scorpion .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990228

*Anti-Mouse IL-10R/CD210 Antibody* (1B1.3A)**	Interleukin Related Parasite Fungal	Infection Metabolic Disease
Anti-Mouse IL-10R/CD210 Antibody (1B1.3A) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse *IL-10R/CD210. Anti-Mouse IL-10R/CD210* Antibody (1B1.3A) blocks IL-10R signaling. Anti-Mouse IL-10R/CD210 Antibody (1B1.3A) can be used for the researches of cancer, infection and metabolic disease, such as diabetes and malaria .

HY-P990001

Anti-Mouse IL-10 Antibody (JES5-2A5) 1 Publications Verification	Interleukin Related	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse IL-10 Antibody (JES5-2A5) is an anti-mouse *IL-10* IgG1 monoclonal antibody. Anti-Mouse IL-10 Antibody (JES5-2A5) restores the anti-tumor activity of IL-6 by blocking the IL-10/SOCS3 axis. Anti-Mouse IL-10 Antibody (JES5-2A5) can reverse microcirculation and cognitive deficits. Anti-Mouse IL-10 Antibody (JES5-2A5) can be used for researches on cancer and metabolic disease such as osteosarcoma and type 1 diabetes mellitus (T1DM) .

HY-P991400

GSK1995057	TNF Receptor Apoptosis Interleukin Related NF-κB JNK p38 MAPK	Inflammation/Immunology
GSK1995057 is a human monoclonal antibody (mAb) targeting TNFRSF1A. GSK1995057 selectively binds to TNFR1, blocks the binding of TNF-α and LT-α, and does not interfere with TNFR2 signaling. GSK1995057 inhibits the activation of NF-κB, JNK and MAPK pathways, alleviates apoptosis (apoptosis) and inflammatory responses (inhibiting IL-1β, IL-6, *IL-10, TNF-α), and prevents viability loss of human nucleus pulposus cells. GSK1995057 inhibits the expression of cytokines and neutrophil adhesion molecules in human pulmonary microvascular endothelial cell monolayers, and reduces inflammatory responses and lung injury symptoms in non-human primates. GSK1995057 forms complexes with HAVH autoantibodies, thereby activating TNFR1* and triggering the release of cytokines and IL-8 in human cells. GSK1995057 can be used in research related to intervertebral disc degeneration and acute lung injury .

HY-P99390

Tepoditamab MCLA 117	CD3 Interleukin Related IFNAR TNF Receptor	Inflammation/Immunology Cancer
Tepoditamab (MCLA-117) is a full-length human IgG1 bispecific monoclonal antibody that binds to CLEC12A of myeloid cells and CD3 of cytotoxic T cells. Among others, CLEC12A is a myeloid differentiation antigen. Tepoditamab kills AML leukaemia mother cells and AML leukaemia stem cells, induces T cell-mediated proliferative lysis of AML cells. Tepoditamab induces upto 30-fold T-cell expansion. Tepoditamab results in moderate to strong cytokine (IFNγ, IL-6, IL-8, IL-10, and TNFα) and IFNγ release in human whole blood and PBMC, respectively. Tepoditamab can be used in acute myeloid leukaemia (AML) research .

HY-P991257

MK-1966 1 Publications Verification	Interleukin Related CXCR MHC	Cancer
MK-1966 is an anti-IL-10 antibody. MK-1966 inhibits secretion of cytokines from activated macrophages, production of CC and CXC chemokines, and a TH1 response, down-regulates MHC and costimulatory molecules on dendritic cells (DCs), and induces regulatory T cells. MK-1966 can be used for the research of cancer , such as gastric cancer .

HY-P990561

BT-063	Interleukin Related	Inflammation/Immunology
BT-063 is a humanized antibody expressed in CHO cells, targeting *IL-10*. BT-063 contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145.74 kDa. The isotype control for BT-063 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P991659

SCH708980	Interleukin Related	Infection Inflammation/Immunology
SCH708980 is a humanized monoclonal antibody inhibitor targeting *IL-10*. SCH708980 has anti-immunosuppressive activity. SCH708980 can be used for visceral leishmaniasis, sepsis-associated kidney injury (SAKI) and osteoporosis research .

HY-P991760

*Anti-IL-10* Antibody (JES3-19F1)**	Interleukin Related	Inflammation/Immunology
Anti-IL-10 Antibody (JES3-19F1) reacts with human IL-10, and is a capture or coating antibody in ELISA applications. Anti-IL-10 Antibody (JES3-19F1) reduces bacterial load in Mycobacterium avium infected mice. Recommend Isotype Controls: Rat IgG2a kappa, Isotype Control (HY-P990679) .

HY-P992038

Anti-IL-10RB Antibody	Interleukin Related	Inflammation/Immunology
Anti-IL-10RB Antibody is an anti-IL-10RB antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992037

Anti-IL-10Rα Antibody	Interleukin Related	Inflammation/Immunology
Anti-IL-10Rα Antibody is an anti-IL-10Rα antibody. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).

HY-P992153

Serrumab	Interleukin Related	Inflammation/Immunology
Serrumab is a human monoclonal antibody that counteracts the biochemical and immunological effects of Tityus serrulatus venom. Serrumab inhibits the TsV-induced increase in the production of IL-6, TNFα and *IL-10*. Serrumab also prevents TsV-induced elevations in plasma urea, creatinine, aspartate transaminase and glucose levels, as well as the TsV-induced increase in neutrophil recruitment. Serrumab can be used in research related to envenoming by the Brazilian yellow scorpion .

Host:	Mouse (11) Rabbit (5)
Reactivity:	Human (15) mouse (1) rat (1) Rat (4) Mouse (3)
Application:	IHC-P (7) ICC/IF (8) IP (1) WB (8) FC (9) ELISA (8)
Isotype:	IgG (5) IgG1 (9) IgG2a (2)
Conjugation:	Non-conjugated (16)
Clonality:	Polyclonal (1) Monoclonal (8) Monoclonal Antibody (1) Recombinant (2)
Modification:	Unmodified (11)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86311

	IL-10 Antibody (YA6003) IL10; Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	IL-10 Antibody (YA6003) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-10.

HY-P85219

	IL-10 Antibody (YA4911) IL10; Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF	WB, ICC/IF, FC	Human, Mouse
	IL-10 Antibody (YA4911) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to IL-10.

HY-P89929

	IL-10 Antibody (YA9273)	WB, FC, ELISA	mouse, rat
	IL-10 Antibody (YA9273) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL-10.

HY-P81113

	IL-10 Antibody (YA3521) Interleukin-10 precursor; Cytokine synthesis inhibitory factor; CSIF; Cytokine Synthesis Inhibitory Factor; IL 10; IL10A; Interleukin 10; Interleukin10; MGC126450; MGC126451; TGIF; IL10_HUMAN. 白介素10	WB, ICC/IF, FC	Human
	IL-10 Antibody (YA3521) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-10.

HY-P84952

	IL-10 Antibody (YA4644) Interleukin-10 precursor; Cytokine synthesis inhibitory factor; CSIF; Cytokine Synthesis Inhibitory Factor; IL 10; IL10A; Interleukin 10; Interleukin10; MGC126450; MGC126451; TGIF; IL10_HUMAN. 白介素10	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	IL-10 Antibody (YA4644) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-10.

HY-P84553

	CD210 Antibody (YA4250) IL10RA; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1	ICC/IF, FC, ELISA	Human
	CD210 Antibody (YA4250) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD210.

HY-P84553A

	CD210 Antibody (YA4250)(PBS only) IL10RA; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1	ICC/IF, FC, ELISA	Human
	CD210 Antibody (YA4250) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD210.

HY-P88511

	IL20 Antibody (YA8195) IL-20; IL10D; ZCYTO10	IHC-P	Human
	IL20 Antibody (YA8195) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to IL20.

HY-P84509

	IL10RB Antibody (YA4206) CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2	WB, FC, ELISA	Human, Rat
	IL10RB Antibody (YA4206) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL10RB.

HY-P84510

	IL10RB Antibody (YA4207) CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2	ICC/IF, FC, ELISA	Human
	IL10RB Antibody (YA4207) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL10RB.

HY-P81240

	IL-19 Antibody IL-19; MDA1; NG.1; ZMDA1; IL-10C	WB, IHC-P	Human
	IL-19 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to IL-19.

HY-P88511A

	IL20 Antibody (YA8195)(PBS only) IL-20; IL10D; ZCYTO10	IHC-P	Human
	IL20 Antibody (YA8195) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to IL20.

HY-P84509A

	IL10RB Antibody (YA4206)(PBS only) CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2	WB, FC, ELISA	Human, Rat
	IL10RB Antibody (YA4206) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL10RB.

HY-P84510A

	IL10RB Antibody (YA4207)(PBS only) CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2	ICC/IF, FC, ELISA	Human
	IL10RB Antibody (YA4207) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL10RB.

HY-P88206

	IL24 Antibody (YA7890) C49A; FISP; IL10B; MDA7; MOB5; ST16	IHC-P	Human
	IL24 Antibody (YA7890) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL24.

HY-P88206A

	IL24 Antibody (YA7890)(PBS only) C49A; FISP; IL10B; MDA7; MOB5; ST16	IHC-P	Human
	IL24 Antibody (YA7890) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL24.

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