1 Result for "

INCB161734

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "INCB161734" in MCE Product Catalog:

Cat. No.: HY-186337
CAS No.: 3125939-25-2
Target:  

Ras

Research Areas:  

Cancer

INCB161734 is a potent, selective, and orally active small-molecule inhibitor of KRAS G12D. INCB161734 binds to the Switch II pocket and inhibits SOS1-dependent GDP/GTP exchange, ERK phosphorylation, and cell proliferation. INCB161734 exhibits antitumor activity in KRAS G12D-mutant tumor models. INCB161734 can be used in research related to KRAS G12D-mutant pancreatic cancer and colorectal cancer .
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