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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Incenp
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Incenp" in MCE Product Catalog:
Research Areas:
SK-3-91 is a multi-kinase PROTAC degrader that induces the degradation of the maximum number of unique kinases (over 125 distinct kinases) simultaneously. SK-3-91 induces protein degradation via the ubiquitin biotinylation (E-STUB) pathway, such as inducing the degradation of YTHDF2. SK-3-91 also inhibits cell proliferation and induces cell morphological changes. SK-3-91 can be used in research related to acute lymphoblastic leukemia, multiple myeloma, neuroblastoma, ovarian cancer, mantle cell lymphoma, and gastric cancer .
Cat. No.: HY-RS06805
Target:
Research Areas:
INCENP Human Pre-designed siRNA Set A contains three designed siRNAs for INCENP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21874
Target:
Research Areas:
Incenp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Incenp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-116190
CAS No.: 1430741-35-7
Target:
Research Areas:
CFI-401870 is an orally active threonine tyrosine kinase (TTK (Mps1)) inhibitor with an IC50 of 3.1 nM. CFI-401870 exhibits IC50s against PLK4, KDR, AURKA and other kinases such as AURKB/INCENP were all greater than 1 μM.CFI-401870 inhibits the growth of various cancer cells, causing chromosome lag, an increase in aneuploidy and cell cycle arrest. CFI-401870 can be used for the study of cancers such as colon cancer .
Cat. No.: HY-RS28391
Target:
Research Areas:
Incenp Rat Pre-designed siRNA Set A contains three designed siRNAs for Incenp gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702967
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Incenp; Binds And Activates Aurora-B And -C In Vivo And In Vitro; Inner Centromere Protein; Inner Centromere Protein Antigens (135kD, 155kD); Inner Centromere Protein Antigens 135/155kDa; Inner Centromere Protein Incenp; FLJ31633; Chromosomal Passenger Pr
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-184329
CAS No.: 3114874-73-3
Target:
Research Areas:
PROTAC AURKB Degrader-1 is a selective AURKB PROTAC degrader with a DC50 value of 0.6 nM. PROTAC AURKB Degrader-1 promotes ubiquitination and degradation of AURKB. PROTAC AURKB Degrader-1 downregulates the expression levels of chromosomal passenger complex components Borealin, INCENP, Survivin as well as the transcription factor YY1. PROTAC AURKB Degrader-1 induces G2/M phase arrest and triggers Apoptosis in cells. PROTAC AURKB Degrader-1 serves as a chemical probe for biological studies of the chromosomal passenger complex. PROTAC AURKB Degrader-1 can be used in research related to acute myeloid leukemia, colorectal cancer, and non-small cell lung cancer .
Cat. No.: HY-P87277
Synonyms: binds and activates aurora B and C in vivo and in vitro antibody; Chromosomal passenger protein antibody; INCE_HUMAN antibody; Incenp antibody; Inner centromere protein antibody; Inner centromere protein antigens 135/155kDa antibody; Inner centromere protein antigens 135kD 155kD antibody; Inner centromere protein Incenp antibody
Cat. No.: HY-P87277A
Synonyms: binds and activates aurora B and C in vivo and in vitro antibody; Chromosomal passenger protein antibody; INCE_HUMAN antibody; Incenp antibody; Inner centromere protein antibody; Inner centromere protein antigens 135/155kDa antibody; Inner centromere protein antigens 135kD 155kD antibody; Inner centromere protein Incenp antibody
Cat. No.: HY-P702867
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: AURKA; Non-Specific Serine/Threonine Protein Kinase; Prev. STK15; Serine/Threonine Protein Kinase 15; Prev. STK6; Serine/Threonine-Protein Kinase 15; BTAK; Ipl1- And Aurora-Related Kinase 1; ARK1; Serine/Threonine Kinase 15; AIK; Serine/Threonine Kinase 6
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705736
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: AURKC; ARK-3; Prev. STK13; AIK3; ARK3; Non-Specific Serine/Threonine Protein Kinase; AurC; Epididymis Secretory Protein Li 90; Serine/Threonine Kinase 13 (Aurora/IPL1-Like); Aurora/IPL1/EG2 Protein 2; Serine/Threonine-Protein Kinase Aurora-C; Aurora/IPL1/
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P703463
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: AURKB; Aurora-1; Prev. STK12; STK-1; AIM-1; AIM1; ARK2; Aurora- And Ipl1-Like Midbody-Associated Protein 1 Homolog (Rat); STK5; Aurora- And Ipl1-Like Midbody-Associated Protein 1 Homolog; PPP1R48; Aurora- And Ipl1-Like Midbody-Associated Protein 1; Aik2; Aurora- And IPL1-Like Midbody-Associated Protein 1; IPL1; Non-Specific Serine/Threonine Protein Kinase; AurB; Aurora Kinase B-Sv1; Protein Phosphatase 1, Regulatory Subunit 48; Aurora Kinase B-Sv2; Serine/Threonine-Protein Kinase Aurora-B; Aurkb-Sv1; Serine/Threonine-Protein Kinase 12; Aurkb-Sv2; Serine/Threonine-Protein Kinase 5; Aurora 1; Aurora/IPL1-Related Kinase 2; AIRK2; Serine/Threonine Kinase 12; STK1; Aurora-Related Kinase 2; AIK2; Aurora-B; Aurora Kinase B; ARK-2; Incenp; Binds And Activates Aurora-B And -C In Vivo And In Vitro; Inner Centromere Protein; Inner Centromere Protein Antigens (135kD, 155kD); Inner Centromere Protein Antigens 135/155kDa; Inner Centromere Protein Incenp; FLJ31633; Chromosomal Passenger Protein
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
