1 Result for "

Lig4-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Lig4-4" in MCE Product Catalog:

Cat. No.: HY-W269032
CAS No.: 3598-68-3
Lig4-4 is an orally active and selective TREK-1 inhibitor, with an IC50 of 2.06 μM in rats. Lig4-4 improves neuronal viability, reduces cell apoptosis by upregulating cleaved-caspase-3 and downregulating Bcl-2, and decreases infarct volume. Lig4-4 exerts a neuroprotective effect against cerebral ischemia injury. Lig4-4 can be used in studies related to cerebral ischemia .
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