46 Results for "

Lysophosphatidylcholine

" in MedChemExpress (MCE) Product Catalog:
Products (46)

46 Results for "Lysophosphatidylcholine" in MCE Product Catalog:

135
135 Publications Verification
Cat. No.: HY-P1410
CAS No.: 1209500-46-8
GsMTx4 is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .
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135
135 Publications Verification
Cat. No.: HY-P1410A
GsMTx4 TFA is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 TFA also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 TFA is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .
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7
7 Cited Publications
Cat. No.: HY-139414
CAS No.: 9008-30-4
Purity:  ≥99.0%
Lysophosphatidylcholines is an orally active lysolipid and a component of oxidized low density lipoprotein (LDL). Lysophosphatidylcholines induces cell injury, the production of IL-1β and apoptosis. Lysophosphatidylcholines has a proactive effect on sepsis .
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2
2 Cited Publications
Cat. No.: HY-125783
CAS No.: 17364-16-8
Purity:  99.92%
Synonyms: 16:0 Lyso PC
1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis .
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1
1 Cited Publications
Cat. No.: HY-125771
CAS No.: 19420-57-6
Purity:  99.53%
Synonyms: 18:0 Lyso-PC; LPC(18:0)
1-Stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine that inhibits HDAC3 activity and phosphorylation of STAT3 in K562 cells. 1-Stearoyl-sn-glycero-3-phosphocholine induces apoptosis and exhibits anticancer activity in chronic myelogenous leukemia (CML) K562 cells .
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1
1 Cited Publications
Cat. No.: HY-W329357
CAS No.: 108273-89-8
15:0 Lyso PC is a lysophosphatidylcholine (Lyso PC), a product of phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine (PC) and is involved in cell membrane remodeling and inflammatory signaling. 15:0 Lyso PC demonstrates significant lipid metabolism disturbances in the serum with ischemic heart disease (IHD) and ischemic cardiomyopathy (ICM). 15:0 Lyso PC can be used as a lipid biomarker for cardiovascular disease .
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1
1 Cited Publications
Cat. No.: HY-P71145
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRDX6; PRX; Peroxiredoxin 6; P29; AiPLA2; Red Blood Cells Page Spot 12; NSGPx; Lyso-PC Acyltransferase 5; AOP2; LPC Acyltransferase 5; Acidic Calcium-Independent Phospholipase A2; Antioxidant Protein 2; Lysophosphatidylcholine Acyltransferase 5; Liver 2D
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-N9410
CAS No.: 22252-07-9
Synonyms: 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC; LPC(18:2/0:0); LysoPC(18:2)
Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary syndrome (PCOS). Low plasma Lysophosphatidylcholine 18:2 also has been shown to predict impaired glucose tolerance, insulin resistance, type 2 diabetes, coronary artery disease, and memory impairment .
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Cat. No.: HY-177475
CAS No.: 60701-99-7
Synonyms: 1-Arachidonoyl-sn-glycero-3-phosphocholine
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease Cancer

LysoPC 20:4 (20:4) (1-Arachidonoyl-sn-glycero-3-phosphocholine) is a serum metabolite. LysoPC 20:4 (20:4) decreases in tumor-bearing mice, but the reduction is not significant. LysoPC (20:4) can be used in cancer and obesity-related research .
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Cat. No.: HY-158790
CAS No.: 2771208-83-2
Purity:  99.29%
Target:  

Ferroptosis

Research Areas:  

Cancer

(R)-HTS-3 is an lysophosphatidylcholine acyltransferase 3 (LPCAT3) inhibitor, with an IC50 of 0.09 μM. (R)-HTS-3 suppresses the C20:4 content of PE, PC, and PS, while promoting a correspondingelevation in C22:4 phospholipids and a paradoxical increase in C20:4 phosphatidylinositol (PI) lipids .
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Cat. No.: HY-W414591
CAS No.: 20559-18-6
Synonyms: 1-Lauroyl-2-hydroxy-sn-glycero-3-phosphatidylcholine; 12:0 Lyso PC
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

L-alpha-lysophosphatidylcholine, lauroyl (1-Lauroyl-2-hydroxy-sn-glycero-3-phosphatidylcholine) is an ester product.
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Cat. No.: HY-157700
CAS No.: 97802-53-4
Synonyms: C16(Plasm) LPC; Lysophosphatidylcholine 16:0p/0:0
Research Areas:  

Neurological Disease

Hexadecenyl-2-hydroxy-sn-glycero-3-PC (C16(Plasm) LPC) is a phosphatidylcholine. Hexadecenyl-2-hydroxy-sn-glycero-3-PC prolongs the lag-phase of α-syn aggregation, and can be used in Parkinson’s disease research .
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Cat. No.: HY-P3029A
CAS No.: 9001-84-7
Synonyms: PLA2, Crotalus adamanteus Venom
Target:  

Phospholipase

Research Areas:  

Others

Phospholipase A2 (PLA2), Crotalus adamanteus Venom is a membrane phospholipid-targeting enzyme. Phospholipase A2, Crotalus adamanteus catalyzes cleavage of the sn-2-acyl bond of membrane phospholipids, producing lysophospholipids and free fatty acids. Phospholipase A2, Crotalus adamanteus Venom can be used for biochemical research .
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Cat. No.: HY-154830
CAS No.: 108273-88-7
Purity:  ≥99.0%
Synonyms: 1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine; 19:0 Lyso PC
Research Areas:  

Others

Lysophosphatidylcholine C19:0 (1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine) is an acyl chain lipid. Lysophosphatidylcholine C19:0 increases IL-1beta secretion .
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Cat. No.: HY-113470
CAS No.: 76790-27-7
Purity:  98.3%
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

LysoPC(16:1(9Z)) is a type of lysophosphatidylcholine that can be used to study spleen deficiency syndrome .
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Cat. No.: HY-164238
CAS No.: 62512-91-8
Research Areas:  

Endocrinology Cancer

LysoPC (18:3) is a type of lysophospholipid metabolite with biomarker properties. LysoPC (18:3) stably exists in human follicular fluid, and its abundance dynamically changes with age, synchronously regulating the body's lipid metabolism process, follicular development process and oocyte maturation process. The down-regulation of LysoPC (18:3) content is associated with breast cancer lesions and follicular aging changes accompanied by in vitro fertilization in elderly women. LysoPC (18:3) can be used in studies related to breast cancer and infertility in elderly women .
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Cat. No.: HY-N9410S
CAS No.: 2162167-92-0
Synonyms: 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC-d9
Lysophosphatidylcholine 18:2-d9 is deuterium labeled Lysophosphatidylcholine 18:2. Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary
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Cat. No.: HY-12812
CAS No.: 1548743-69-6
Purity:  99.40%
Research Areas:  

Neurological Disease Cancer

Autotaxin modulator 1 is an autotaxin (ATX) enzyme inhibitor, extracted from patent WO 2014018881 A1, Compound Example 12b. Autotaxin modulator 1 is expected to be useful for researching demyelination due to injury or disease, as well as for researching proliferative disorders such as cancer .
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Cat. No.: HY-125783S1
CAS No.: 327178-91-6
Purity:  ≥99.0%
Synonyms: 16:0 Lyso PC-d31
1-Palmitoyl-sn-glycero-3-phosphocholine-d31 (16:0 Lyso PC-d31) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis .
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Cat. No.: HY-126233
CAS No.: 1689554-51-5
Research Areas:  

Others

PAT-347 is an inhibitor of autotaxin (ATX, ENPP-2) . PAT-347 binds only to the hydrophobic channel of ATX, without occupying its hydrophobic pocket and catalytic site . PAT-347 blocks the binding of lysophosphatidylcholine (LPC) to the catalytic site of ATX .
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