1 Result for "

MA191

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MA191" in MCE Product Catalog:

Cat. No.: HY-175273
Research Areas:  

Cancer

MA191 is a FLT3 PROTAC degrader. MA191 targets and degrades mutant FLT3-ITD protein by recruiting the VHL E3 ligase in a manner dependent on ubiquitination and BIM, thereby blocking aberrant downstream MAPK/STAT5 signaling pathways and inducing apoptosis. MA191 can be used in research related to acute myeloid leukemia .
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