2 Results for "

MACTIDE

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "MACTIDE" in MCE Product Catalog:

Cat. No.: HY-P10947
Research Areas:  

Cancer

MACTIDE-V is an orally active and selective peptide-drug conjugate targeting CD206. MACTIDE-V delivers Verteporfin (HY-B0146) to CD206 + tumor-associated macrophages (TAM) to inhibit the YAP/TAZ signaling pathway, prompting YAP exclusion from the nucleus, inducing TAM polarization toward an anti-tumoral phenotype with enhanced phagocytosis and antigen presentation, and boosting T cell infiltration and NK cell activity. MACTIDE-V suppresses primary tumor growth and lung metastasis in triple-negative breast cancer (TNBC) mouse models .
loading...
    loading...
Cat. No.: HY-P11217
CAS No.: 3103331-32-1
Research Areas:  

Cancer

MACTIDE is a CD206 targeting peptide with high affinity and stability. MACTIDE is commonly used to enhance the targeting of drugs. MACTIDE can be used in the research of cancer such as breast cancer .
loading...
    loading...