1 Result for "

MAZ51

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MAZ51" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-116624
CAS No.: 163655-37-6
Purity:  99.76%
Target:  

VEGFR Apoptosis

Research Areas:  

Cancer

MAZ51 is a selective inhibitor of VEGFR-3 (Flt-4) tyrosine kinase. MAZ51 inhibits VEGF-C-induced activation of VEGFR-3 without blocking VEGF-C-mediated stimulation of VEGFR2. MAZ51 had no effect on ligand-induced autophosphorylation of EGFR, IGF-1R and PDGFRβ. MAZ51 blocks proliferation and induces apoptosis in a wide variety of tumor cells. Antitumor activity .
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