1 Result for "

ML351

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ML351" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-111310
CAS No.: 847163-28-4
Purity:  99.16%
Target:  

Lipoxygenase

ML351 is a potent and highly specific 15-LOX-1 inhibitor with an IC50 of 200 nM. ML351 shows excellent selectivity (>250-fold) versus the related isozymes, 5-LOX, platelet 12-LOX, 15-LOX-2, ovine COX-1, and human COX-2 [1]. ML351 prevents dysglycemia and reduces β-cell oxidative stress in nonobese diabetic mouse model of T1D .
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