1 Result for "

MMI166

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MMI166" in MCE Product Catalog:

Cat. No.: HY-183408
CAS No.: 193809-84-6
Target:  

MMP Apoptosis

Research Areas:  

Cancer

MMI-166 is an orally active selective matrix metalloproteinase (MMP) inhibitor (MMP-2 (IC50 = 2 nM), MMP-9 (IC50 = 53 nM)). MMI-166 can prevent tumor invasion, metastasis and angiogenic, and promotes apoptosis. MMI-166 dose not only directly inhibits the enzymatic activity of MMP-2 and MMP-9 but also downregulates their protein synthesis and expression levels at the post-transcriptional level. MMI-166 can be used in research on colon cancer, head and neck squamous cell carcinoma, microglioma, lung cancer, and pancreatic cancer .
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