34 Results for "

N-hydroxysuccinimide ester

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "N-hydroxysuccinimide ester" in MCE Product Catalog:

23
23 Publications Verification
Cat. No.: HY-D0802
CAS No.: 35013-72-0
Synonyms: Biotin N-hydroxysuccinimide ester; NHS-Biotin
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
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8
8 Cited Publications
Cat. No.: HY-Y0623
CAS No.: 6066-82-6
Synonyms: HOSu; 1-Hydroxy-2,5-pyrrolidinedione
N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is a covalent crosslinker commonly used in bioconjugation technology with a primary amine group. N-Hydroxysuccinimide reacts with amino groups (-NH2) to form a stable amide bond, which can modify amino-containing biomolecules. N-Hydroxysuccinimide can be used, for example, for protein labeling with fluorescent dyes and enzymes, surface activation of chromatography supports, microbeads, nanoparticles and microarray slides, and chemical synthesis of peptides. N-Hydroxysuccinimide has a wide range of applications in biomaterial synthesis (such as collagen, chitosan crosslinking), drug delivery systems (such as hydrogel preparation) and tissue engineering .
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5
5 Cited Publications
Cat. No.: HY-D0975
CAS No.: 92921-24-9
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
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4
4 Cited Publications
Cat. No.: HY-15937
CAS No.: 117548-22-8
Synonyms: 5(6)-Carboxyfluorescein N-hydroxysuccinimide ester; 5(6)-Carboxyfluorescein succinimidyl ester mixed isomers
5(6)-FAM SE is a green fluorescent dye widely used for protein labeling.
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1
1 Cited Publications
Cat. No.: HY-42360
CAS No.: 64987-85-5
Target:  

ADC Linkers

Research Areas:  

Others

SMCC is a protein crosslinker. SMCC contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses .
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1
1 Cited Publications
Cat. No.: HY-W013151
CAS No.: 114932-60-4
Research Areas:  

Others

1-Pyrenebutyric acid N-hydroxysuccinimide ester (PANHS) is a linker and interface coupling agent that can be used to prepare electrochemical biosensors. 1-Pyrenebutyric acid N-hydroxysuccinimide ester immobilizes SARS-CoV-2 spike antibodies on graphene sheets. 1-Pyrenebutyric acid N-hydroxysuccinimide ester is often used as an activation reagent for carboxylic acids in organic chemistry or biochemistry .
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Cat. No.: HY-78961
CAS No.: 55750-63-5
Synonyms: EMCS
Target:  

ADC Linkers

Research Areas:  

Cancer

6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates .
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Cat. No.: HY-137383
CAS No.: 102568-43-4
Purity:  99.72%
Sulfo-SANPAH is a primary amine-nitrobenzene azide cross-linker. Sulfo-SANPAH improves the functionalization process of PDMS surfaces, is covalently bound to the PAAm gel surface. Sulfo-SANPAH is widely used to crosslink ECM proteins to various substrates, including acrylic-based hydrogels, such as polyacrylamide hydrogels. Sulfo-SANPAH facilitates covalent binding through its negatively charged sulfonate group on its N-hydroxysuccinimide ester ring and a photoactivated phenyl azide group that is highly reactive with nucleophiles and free radicals .
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Cat. No.: HY-153631
CAS No.: 482618-42-8
Research Areas:  

Inflammation/Immunology

Sulfo-TAG NHS ester disodium is an N-hydroxysuccinimide ester that can be coupled to proteins via primary amine groups. Sulfo-TAG NHS ester disodium can be used for antibody labeling .
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Cat. No.: HY-W011541
CAS No.: 39028-27-8
Synonyms: Iodoacetic acid N-hydroxysuccinimide ester; N-Succinimidyl Iodoacetate
Target:  

ADC Linkers

Research Areas:  

Cancer

SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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Cat. No.: HY-W105423
CAS No.: 38862-25-8
Synonyms: NHS-MA
Methacrylic acid N-hydroxysuccinimide ester (NHS-MA) is a polymer that serves as a monomer to prepare degradable amphiphilic block copolymer microparticles via RAFT polymerization for low pH-triggered drug delivery. Methacrylic acid N-hydroxysuccinimide ester is used for the synthesis of nanogels .
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Cat. No.: HY-170528
CAS No.: 2249926-63-2
Target:  

PROTAC Linkers

Research Areas:  

Others

DBCO-PEG3-NHS is a biochemical assay reagent, that can be used to chemically modify proteins and antibodies with an alkynyl (DBCO) or N-hydroxysuccinimide (NHS) ester group. DBCO-PEG3-NHS can be used as a linker in PROTAC synthesis or for drug delivery and the development of biosensors and diagnostic reagents .
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Cat. No.: HY-W011134
CAS No.: 14464-31-4
Research Areas:  

Others

Palmitic acid N-hydroxysuccinimide is used to conjugate proteins to prepare targeted delivery vectors. Palmitic acid N-hydroxysuccinimide can be used as lipophilic electrophile. Palmitic acid N-hydroxysuccinimide can be used for the covalent connection between palmitic acid and ovalbumin. Palmitic acid N-hydroxysuccinimide can be used to synthesize cetacyl derivatives of amino acids, aminoacyl-trNA, coenzyme A, mercaptoacetic acid and other amino and thiogenic compounds .
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Cat. No.: HY-150014
CAS No.: 2925268-86-4
Purity:  98.55%
Target:  

Others

Research Areas:  

Others

AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells .
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Cat. No.: HY-D0967
CAS No.: 146368-15-2
Cy5-bifunctional dye is a bifunctional dye used for covalent labeling of primary amines on proteins or oligonucleotides (Ex/Em = 649 nm/670 nm). Cy5-bifunctional dye can label recombinant annexin-V to assess phosphatidylserine exposure on the cell surface via flow cytometry. Cy5-bifunctional dye can label anti-human IgG (H + L) secondary antibodies. Cy5-bifunctional dye is applicable to studies of glanders and melioidosis .
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Cat. No.: HY-W021068
CAS No.: 58626-38-3
Research Areas:  

Others

3-Maleimidobenzoic acid N-hydroxysuccinimide ester is used as asymmetric spacers .
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Cat. No.: HY-W043748
CAS No.: 38862-24-7
Synonyms: N-Succinimidyl acrylate
Research Areas:  

Others

2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a lysine residue modifier and coupling monomer. 2,5-Dioxopyrrolidin-1-yl acrylate covalently modifies the primary amines of lysine residues on monoclonal anti-horseradish peroxidase IgG antibodies, neutralizes positive charges and replaces them with low-affinity acrylate groups. 2,5-Dioxopyrrolidin-1-yl acrylate inhibits the formation of rapid hard coronas on citrate-coated gold nanoparticles, induces antibody unfolding and loss of antigen-binding function, but does not affect the antigen-binding function of antibodies in free solution. 2,5-Dioxopyrrolidin-1-yl acrylate reacts with the ε-amino groups on lysine residues of L-asparaginase, introduces vinyl groups and generates N-hydroxysuccinimide. 2,5-Dioxopyrrolidin-1-yl acrylate regulates the activity of L-asparaginase .
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Cat. No.: HY-P5299
CAS No.: 114726-49-7
Research Areas:  

Others

Fmoc-Gly-Gly-OSu is a dipeptide linker intermediate composed of glycine residues, with its N-terminus protected by Fmoc and C-terminus activated by N-hydroxysuccinimide (OSu). Fmoc-Gly-Gly-OSu can be used for the synthesis of ADC linker .
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Cat. No.: HY-140339
CAS No.: 60117-35-3
Purity:  98.02%
Research Areas:  

Others Cancer

ANB-NOS is a heterobifunctional crosslinker with lipophilic, uncharged properties suitable for intracellular conjugation. ANB-NOS contains an amine-reactive Nhydroxysuccinimide (NHS) ester and a photoactivatable nitrophenyl azide. ANB-NOS can be used for the research of fibrosarcoma and mammary adenocarcinoma .
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Cat. No.: HY-150311
Purity:  ≥95.0%
Target:  

PROTAC Linkers

Research Areas:  

Others

endo-BCN-PEG24-NHS ester is composed of a benzocyclonorbornene, a twenty-tetramer of polyethylene glycol (PEG) and an N-hydroxysuccinimide ester. endo-BCN-PEG24-NHS is utilized as linker for synthesis of PROTAC molecule .
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