102568-43-4
Chemical Structure
Sulfo-SANPAH
- CAS No.: 102568-43-4
- Formula:C16H18N6O9S
- Molecular Weight:470.41
IUPAC Name: 1-((6-((4-azido-2-nitrophenyl)amino)hexanoyl)oxy)-2,5-dioxopyrrolidine-3-sulfonic acid
InChIKey: UPNUQQDXHCUWSG-UHFFFAOYSA-N
SMILES: O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCCCNC2=CC=C(N=[N+]=[N-])C=C2[N+]([O-])=O
Biological Activity: Sulfo-SANPAH is a primary amine-nitrobenzene azide cross-linker. Sulfo-SANPAH improves the functionalization process of PDMS surfaces, is covalently bound to the PAAm gel surface. Sulfo-SANPAH is widely used to crosslink ECM proteins to various substrates, including acrylic-based hydrogels, such as polyacrylamide hydrogels. Sulfo-SANPAH facilitates covalent binding through its negatively charged sulfonate group on its N-hydroxysuccinimide ester ring and a photoactivated phenyl azide group that is highly reactive with nucleophiles and free radicals[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sulfo-SANPAH | 99.75% | Sulfo-SANPAH is a primary amine-nitrobenzene azide cross-linker. Sulfo-SANPAH improves the functionalization process of PDMS surfaces, is covalently bound to the PAAm gel surface. Sulfo-SANPAH is widely used to crosslink ECM proteins to various substrates, including acrylic-based hydrogels, such as polyacrylamide hydrogels. Sulfo-SANPAH facilitates covalent binding through its negatively charged sulfonate group on its N-hydroxysuccinimide ester ring and a photoactivated phenyl azide group that is highly reactive with nucleophiles and free radicals. | ||||||||||||||||||||
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- [1]. Vázquez-Victorio G, et al. Fabrication of Adhesive Substrate for Incorporating Hydrogels to Investigate the Influence of Stiffness on Cancer Cell Behavior. Methods Mol Biol. 2021;2174:277-297. [Content Brief]
- [2]. Pérez-Calixto, M., et al., (2025). Enhanced PDMS Functionalization for Organ-on-a-Chip Platforms Using Ozone and Sulfo-SANPAH: A Simple Approach for Biomimetic Long-Term Cell Cultures. Advanced healthcare materials, 14(13), e2404686. Advance online publication. [Content Brief]
Keywords
