2. Search Result
Search Result
Results for "

Nicotiana

" in MedChemExpress (MCE) Product Catalog:

48

Inhibitors & Agonists

1

Biochemical Assay Reagents

3

Peptides

27

Natural
Products

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N4283
    Coniferyl alcohol

    		Drug Intermediate Fungal Infection Cardiovascular Disease Inflammation/Immunology
    Coniferyl alcohol is an orally active lignin biosynthesis intermediate and antifungal agent. Coniferyl alcohol specifically inhibits the growth of fungi (Verticillium longisporum). Coniferyl alcohol inhibits the growth of Nicotiana benthamiana seedlings. Coniferyl alcohol improves cardiac dysfunction in renovascular hypertension and cardiac inflammation .
    Coniferyl alcohol
  • HY-W002112
    (±)-Nornicotine

    Nornicotine

    		 Endogenous Metabolite Drug Metabolite nAChR β-catenin Cardiovascular Disease Neurological Disease
    (±)-Nornicotine is a major metabolite of Nicotine. (±)-Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. (±)-Nornicotine disrupts β-catenin and ZO-1, and induces F-actin depolymerization. (±)-Nornicotine supports self-administration behavior. (±)-Nornicotine can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia .
    (±)-Nornicotine
  • HY-B1532
    Anabasine

    (S)-Anabasine; (+)-Anabasine

    		 Environmental Pollutants nAChR Neurological Disease
    Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
    Anabasine
  • HY-N7400
    Phaseoloidin

    		NOD-like Receptor (NLR) Caspase Autophagy Apoptosis AMPK mTOR Insecticide Inflammation/Immunology
    Phaseoloidin is an orally active multi-target inhibitor. Phaseoloidin inhibits the activation of the NLRP3 inflammasome and blocks the caspase-11-GSDMD pyroptosis axis. Phaseoloidin reduces the expression of collagen-degrading enzymes to maintain the integrity of cartilage matrix. Phaseoloidin activates the AMPK/mTOR pathway to enhance autophagy function and reverse apoptosis resistance. Phaseoloidin inhibits the growth and development of Manduca sexta and Spodoptera littoralis larvae, thereby helping Nicotiana attenuata defend against lepidopteran herbivorous insects. Phaseoloidin can be used in research related to acute gouty arthritis and pulmonary fibrosis .
    Phaseoloidin
  • HY-N8723
    (1′S,2′S)-Nicotine-1'-oxide

    		Others Neurological Disease
    (1′S,2′S)-Nicotine-1'-oxide is an alkaloid N-oxide from the leaves, stems and roots of Nicotiana tabacum .
    (1′S,2′S)-Nicotine-1'-oxide
  • HY-W001084
    Methyl 4-hydroxyphenylacetate

    		Others Infection Cancer
    Methyl 4-hydroxyphenylacetate is a compound found in the marine fungus Penicillium oxalicum 0312F1. Methyl 4-hydroxyphenylacetate can be Methyl 4-hydroxyphenylacetate inhibits replication of tobacco mosaic virus (TMV) in Nicotiana tabacum leaf discs. Methyl 4-hydroxyphenylacetate shows inhibitory activity against proliferation of cancer cells. Methyl 4-hydroxyphenylacetate can be used for the researches of TMV infection and cancer .
    Methyl 4-hydroxyphenylacetate
  • HY-N13047
    Ningnanmycin

    		TMV SOD Infection
    Ningnanmycin is a plant antiviral agent. Ningnanmycin binds to specific residues on the TMV CP disc, inhibits CP assembly, disassembles the CP disc into monomers, and disrupts the structure of the TMV CP disc to reduce pathogenicity. Ningnanmycin binds to key amino acids of PVY CP, interferes with CP-CP interactions, inhibits CP assembly and virion formation, and blocks PVY replication. Ningnanmycin induces the expression of antiviral response genes PRXIIB, PRXIIE, PUB4 and PER42, thereby activating the host defense system. Ningnanmycin can be used in studies related to Tobacco Mosaic Virus infection and Potato Virus Y infection .
    Ningnanmycin
  • HY-B0941A
    6-Benzylaminopurine, suitable for plant cell culture

    Benzyladenine, suitable for plant cell culture; 6-BAP, suitable for plant cell culture; N6-Benzyladenine, suitable for plant cell culture

    		 Biochemical Assay Reagents Others
    6-Benzylaminopurine,suitable for plant cell culture is a cytokinin that induces plant growth and development by stimulating cell division, and prolongs the freshness of green vegetables through inhibiting respiratory kinases .
    6-Benzylaminopurine, suitable for plant cell culture
  • HY-N1033
    12-Hydroxyjasmonic acid

    		Phytohormone Drug Metabolite Glycosyltransferase Infection
    12-Hydroxyjasmonic acid is a metabolite of Jasmonic acid (HY-122464A) and an inducer of defense responses. 12-Hydroxyjasmonic acid can be isolated from potato leaflets. During the response of sugar beet plants to Cercospora beticola infection, 12-Hydroxyjasmonic acid is released through deglycosylation of its glucoside form and participates in the Jasmonic acid-mediated defense signaling pathway. 12-Hydroxyjasmonic acid mediates changes in source-sink relationships during pathogen infection, prioritizing the activation of defense processes over growth processes. 12-Hydroxyjasmonic acid serves as a substrate for salicylic acid Glycosyltransferases in tobacco and rice. 12-Hydroxyjasmonic acid can induce leaflet closure in Samanea saman. 12-Hydroxyjasmonic acid acts as a potato tuber-inducing substance. 12-Hydroxyjasmonic acid does not induce protoplast shrinkage in extensor motor cells of Samanea saman. 12-Hydroxyjasmonic acid can be used in studies related to brown spot disease .
    12-Hydroxyjasmonic acid
  • HY-N15133
    Solanacol

    (-)-Solanacol

    		 Drug Derivative Others
    Solanacol ((-)-Solanacol) is a strigolactone germination stimulant that can be isolated from tobacco (Nicotiana tabacum L.). Solanacol stimulates the germination of root parasitic weed seeds .
    Solanacol
  • HY-118614
    β-Nicotyrine

    		Drug Metabolite Neurological Disease
    β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid .
    β-Nicotyrine
  • HY-178977
    PPO-IN-23

    		Herbicide Others
    PPO-IN-23 is a potent protoporphyrinogen IX oxidase (PPO) inhibitor with a Ki of 12.4 nM. PPO-IN-23 forms two hydrogen bonds with the Arg98 residue of Nicotiana tabacum PPO (NtPPO). PPO-IN-23 exhibits potent herbicidal activity and good crop safety. PPO-IN-23 can be used for weeds management .
    PPO-IN-23
  • HY-178026
    HPPD/PPO-IN-1

    		HPPD Protoporphyrinogen IX oxidase Others
    HPPD/PPO-IN-1 (Compound B14) is dual-functional inhibitor of HPPD and PPO with IC50s of 0.12  μM and 0.51 μM for Arabidopsis thaliana HPPD and Nicotiana tabacum PPO, respectively. HPPD/PPO-IN-1 has broad-spectrum herbicidal activity against weeds with a crop safety to peanuts and cotton. HPPD/PPO-IN-1 can be used for the development of environmentally friendly herbicides .
    HPPD/PPO-IN-1
  • HY-119963A
    trans-β-Terpineol

    		Bacterial Infection Inflammation/Immunology
    trans-β-Terpineol is a cyclic monoterpene alcohol present in Greek propolis and the essential oil of Peganum harmala seeds, with biological activities. trans-β-Terpineol serves as a substrate for biotransformation in tobacco suspension cells, where allylic hydroxylation occurs at specific sites. trans-β-Terpineol can be isolated from the leaves of Euryops arabicus. Terpineol (HY-N7851) exhibits antioxidant and antibacterial activities, and trans-β-terpineol is the bioactive compound responsible for the antibacterial effect in Euryops arabicus .
    trans-β-Terpineol
  • HY-W001084R
    Methyl 4-hydroxyphenylacetate (Standard)

    		Reference Standards Others
    Methyl 4-hydroxyphenylacetate (Standard) is the analytical standard of Methyl 4-hydroxyphenylacetate (HY-W001084). This product is intended for research and analytical applications. Methyl 4-hydroxyphenylacetate is a compound found in the marine fungus Penicillium oxalicum 0312F1. Methyl 4-hydroxyphenylacetate can be Methyl 4-hydroxyphenylacetate inhibits replication of tobacco mosaic virus (TMV) in Nicotiana tabacum leaf discs. Methyl 4-hydroxyphenylacetate shows inhibitory activity against proliferation of cancer cells. Methyl 4-hydroxyphenylacetate can be used for the researches of TMV infection and cancer .
    Methyl 4-hydroxyphenylacetate (Standard)
  • HY-N6085
    N-​Caffeoylputrescine,​(E)​-

    		Others Others
    N-​Caffeoylputrescine,​(E)​- is a caffeic acid amide found in the tobacco plants (Nicotiana tabacum L.) .
    N-​Caffeoylputrescine,​(E)​-
  • HY-N4283R
    Coniferyl alcohol (Standard)

    		Reference Standards Drug Intermediate Fungal Infection Cardiovascular Disease Inflammation/Immunology
    Coniferyl alcohol is an orally active lignin biosynthesis intermediate and antifungal agent. Coniferyl alcohol specifically inhibits the growth of fungi (Verticillium longisporum). Coniferyl alcohol inhibits the growth of Nicotiana benthamiana seedlings. Coniferyl alcohol improves cardiac dysfunction in renovascular hypertension and cardiac inflammation .
    Coniferyl alcohol (Standard)
  • HY-N8459
    α-Cembrenediol

    α-CBD

    		 EBV Cancer
    α-Cembrenediol is a potent inhibitor of EBV.α-Cembrenediol inhibits the early antigen of the Epstein-Bar virus. α-Cembrenediol also has anti-tumour activity .
    α-Cembrenediol
  • HY-121858
    Nicotianamine

    		Angiotensin-converting Enzyme (ACE) Metabolic Disease
    Nicotianamine can be isolated from the leaves of Nicotiana Tabacum L.. Nicotianamine is a key biosynthetic precursor of phytosiderophores. Nicotianamine is an iron chelating agent and can promote the transport of iron. Nicotianamine is an angiotensin-converting enzyme (ACE) inhibitor with IC50 values of 76 nM and 59 nM for rhACE2 and rhACE, respectively. Nicotianamine is vital in metal nutrition and metal homeostasis of flowering plants .
    Nicotianamine
  • HY-N3890
    Exoticin

    		Others Others
    Exoticin is a natural product that can be isolated from the leaves of Nicotiana plumbaginifolia .
    Exoticin
  • HY-W014928
    Anabasine hydrochloride

    (S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride

    		 nAChR Neurological Disease
    Anabasine ((S)-Anabasine) hydrochloride is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 µM) .
    Anabasine hydrochloride
  • HY-N10425
    2-Hydroxyalbrassitriol

    		Cholinesterase (ChE) Neurological Disease
    2-Hydroxyalbrassitriol (Compound 6) is an AChE inhibitor with an IC50 of 35.97 μM .
    2-Hydroxyalbrassitriol
  • HY-W653822
    (2'S)-Nicotine 1-oxide

    (2S)-Nicotine 1-N-oxide

    		 Drug Metabolite Others
    (2'S)-Nicotine 1-oxide ((2S)-Nicotine 1-N-oxide) is an alkaloid N-oxide, which is found in leaves, stems and roots of Nicotiana tabacum .
    (2'S)-Nicotine 1-oxide
  • HY-159488
    PPO-IN-14

    		Protoporphyrinogen IX oxidase Others
    PPO-IN-14 (compound B11) is a Nicotiana tobacco Protoporphyrinogen oxidase (NtPPO) inhibitor, with a Ki value of 9.05 nM. PPO-IN-14 (compound B11) could help control weeds in agricultural production .
    PPO-IN-14
  • HY-164510
    N-Formyldemecolcine

    		Cytochrome P450 Others
    N-Formyldemecolcine is a colchicine precursor that contains the characteristic tropolone ring and pharmacophore of colchicine. N-Formyldemecolcine can be synthesized de novo by genetically engineering transgenic Nicotiana benthamiana and atypical cytochrome P450s that catalyze the production of colchicine's unique carbon scaffold .
    N-Formyldemecolcine
  • HY-N6740R
    Beta-Zearalanol (Standard)

    		Reference Standards Apoptosis Metabolic Disease
    (±)-Nornicotine (Standard) is the analytical standard of (±)-Nornicotine. This product is intended for research and analytical applications. (±)-Nornicotine is the primary metabolite of nicotine that is formed through demethylation of nicotine in the genus Nicotiana tabacum L. (±)-Nornicotine is a precursor of tobacco-specific nitrosamine N-nitrosonornicotine. (±)-Nornicotine has detrimental effects to human health .
    Beta-Zearalanol (Standard)
  • HY-163570
    PPO-IN-11

    		Protoporphyrinogen IX oxidase Others
    PPO-IN-11 (Compound 10bh) is an inhibitor for protoporphyrinogen IX oxidase (PPO), that inhibits nicotiana tabacum PPO (NtPPO) with Ki of 0.0603 μM. PPO-IN-11 exhibits herbicidal activities against dicot weeds Leaf mustard, Chickweed, Chenopodium serotinum and monocot weeds Alopecurus aequalis, Poa annua, and Polypogon fugax with a dose of 150 g a.i./ha .
    PPO-IN-11
  • HY-B1532R
    Anabasine (Standard)

    (S)-Anabasine (Standard); (+)-Anabasine (Standard)

    		 Reference Standards nAChR Neurological Disease
    Anabasine (Standard) is the analytical standard of Anabasine. This product is intended for research and analytical applications. Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
    Anabasine (Standard)
  • HY-W002112R
    (±)-Nornicotine (Standard)

    Nornicotine (Standard)

    		 Reference Standards Endogenous Metabolite Drug Metabolite nAChR β-catenin Cardiovascular Disease Neurological Disease
    (±)-Nornicotine (Standard) is the analytical standard of (±)-Nornicotine (HY-W002112). This product is intended for research and analytical applications. (±)-Nornicotine is a major metabolite of Nicotine. (±)-Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. (±)-Nornicotine disrupts β-catenin and ZO-1, and induces F-actin depolymerization. (±)-Nornicotine supports self-administration behavior. (±)-Nornicotine can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia .
    (±)-Nornicotine (Standard)
  • HY-N12475
    Solavetivone

    		Fungal Cytochrome P450 Infection
    Solavetivone is a Sesquiterpenoid phytoalexin and Antifungal agent. Solavetivone is isolated from stress-challenged potato plants. Solavetivone is hydroxylated by sesquiterpenoid phytoalexin hydroxylase (SPH/CYP76A2L). Solavetivone helps solanaceous plants defend against pathogens, damages plant cells after pathogen threat, and inhibits mycelial growth of Rhizoctonia solani. Solavetivone is applicable to studies related to Rhizoctonia solani infection .
    Solavetivone
  • HY-118614R
    β-Nicotyrine (Standard)

    		Reference Standards Drug Metabolite Neurological Disease
    β-Nicotyrine (Standard) is the analytical standard of β-Nicotyrine. This product is intended for research and analytical applications. β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid .
    β-Nicotyrine (Standard)
  • HY-N18041
    Pseudostellarin E

    		Drug Derivative Others
    Pseudostellarin E is a proline-rich, caryophyllaceous cyclopeptide present in the roots of Pseudostellaria heterophylla. Pseudostellarin E can be synthesized by overexpressing its precursor gene prePhPE in the leaves of Nicotiana benthamiana .
    Pseudostellarin E
  • HY-180756
    p-Coumaroylputrescine

    		Nucleoside Antimetabolite/Analog Others
    p-Coumaroylputrescine is a product found in the callus tissue culture of Nicotiana tabacum .
    p-Coumaroylputrescine
  • HY-N15360
    Isophytyl acetate

    		Herbicide Infection
    Isophytyl acetate is an organic compound found in Nicotiana plumbaginifolia stems. Isophytyl acetate is promising for research of herbicides .
    Isophytyl acetate
  • HY-162417
    PPO-IN-12

    		Herbicide Others
    PPO-IN-12 (Compound E-Ic) an inhibitor for nicotiana tabacum protoporphyrinogen IX oxidase (NtPPO), with the Ki of 3 nM. Antibacterial agent 208 exhibits a board herbicide spectrum, with good inhibitory activity against broadleaf weeds .
    PPO-IN-12
  • HY-173015
    PPO-IN-16

    		Herbicide Protoporphyrinogen IX oxidase Others
    PPO-IN-16 (Compound D5) is a PPO inhibitor and herbicide with a Ki of 33.7 nM against Nicotiana tabacum PPO (NtPPO). PPO-IN-16 has a broad herbicidal spectrum and exhibits good safety on crops such as wheat, rice, and peanut .
    PPO-IN-16
  • HY-178107
    PPO-IN-21

    		Protoporphyrinogen IX oxidase Herbicide Others
    PPO-IN-21 (Compound A20) is a protoporphyrinogen IX oxidase (PPO) inhibitor with a Ki of 15.2 nM for Nicotiana tabacum PPO. PPO-IN-21 has inhibitory activity against various weeds (including monocots and dicots). PPO-IN-21 can be used as herbicide .
    PPO-IN-21
  • HY-N18278
    Epicatechin-5-O-β-D-glucopyranoside

    		Drug Derivative Others
    Epicatechin-5-O-β-D-glucopyranoside (Compound 9) is a glucoside. Epicatechin-5-O-β-D-glucopyranoside forms via regioselective 5-O-β-D-glucosylation of epicatechin of quercetin 3-O-D-glucoside .
    Epicatechin-5-O-β-D-glucopyranoside
  • HY-173058
    NtPPO-IN-1

    		Herbicide Protoporphyrinogen IX oxidase Others
    NtPPO-IN-1 (Compound A4) is the inhibitor for Nicotiana tabacum PPO (NtPPO) with a Ki of 9.05 nM. NtPPO-IN-1 exhibits herbicidal activity against Setaria viridis, Echinochloa crus-galli, Digitaria sanguinalis, Amaranthus retroflexus, Abutilon theophrasti and Portulaca oleracea, and exhibits 30-50% injury to corn and rice (150 g a.i./ha) .
    NtPPO-IN-1
  • HY-176531
    Antiviral agent 69

    		Others Infection
    Antiviral agent 69 (Compound L2) is a capsid protein residue THR155-targeting inhibitor of phytoviral intercellular traffic. Antiviral agent 69 has an excellent antiviral activity against Potato virus Y (PVY) with an EC50 of 128.10 μg/mL for inactivation effect. Antiviral agent 69 effectively decreases viral accumulation in host plant Nicotiana benthamiana, promising for novel pesticide research and development .
    Antiviral agent 69
  • HY-172151
    PPO-IN-17

    		Herbicide Protoporphyrinogen IX oxidase Others
    PPO-IN-17 (Compound 6R) is the inhibitor protoporphyrinogen IX oxidase (PPO) that inhibits Nicotiana tobacco PPO (NtPPO) with Ki of 30.34 nM. PPO-IN-17 exhibits herbicidal activity that inhibits barnyardgrass (E. crus-galli), foxtail grass (D. sanguinalis), alfalfa (M. sativa) and Canada cocklebur (C. canadensis) (>95% inhibition rate at a concentration of 37.5 g/hm 2). PPO-IN-17 exhibits no toxicity on rice (at a concentration of 75 g/hm 2) or on honeybees (at a concentration of 6400 mg/kg) .
    PPO-IN-17
  • HY-N17527
    7-Demethoxytylophorine N-oxide

    		Others Infection
    7-Demethoxytylophorine N-oxide is an alkaloid inhibitor of Tobacco Mosaic Virus. 7-Demethoxytylophorine N-oxide can be isolated from the aerial parts of Cynanchum komarovii. 7-Demethoxytylophorine N-oxide is applicable to research related to Tobacco Mosaic Virus infection .
    7-Demethoxytylophorine N-oxide
  • HY-182897
    PPO-IN-25

    		Herbicide Others
    PPO-IN-25 (Compound B2) is a PPO inhibitor and Herbicide, with a Ki value of 9.50 nM against NtPPO. PPO-IN-25 exhibits control efficacy against broadleaf weeds and shows broad-spectrum herbicidal activity. PPO-IN-25 can be used in studies related to weed damage .
    PPO-IN-25
  • HY-W719455
    Pungenin

    		Lipase Others
    Pungenin is a compound that can be isolated from Leontopodium leontopodioides. Pungenin exhibits lipase inhibitory activity. Pungenin reuduces triglyceride absorption .
    Pungenin
  • HY-W748338
    Flumiclorac-pentyl

    		Herbicide Protoporphyrinogen IX oxidase Others
    Flumiclorac-pentyl is a herbicide and NtPPO inhibitor, with a Ki value of 46.02 nM against NtPPO. Flumiclorac-pentyl exhibits herbicidal activity against Abutilon theophrasti, Amaranthus retroflexus, Portulaca oleracea, Setaria viridis, Digitaria sanguinalis and Echinochloa crusgalli .
    Flumiclorac-pentyl
  • HY-W681749
    Morphactin Chlorflurenol methyl

    Morphactin

    		 Biochemical Assay Reagents Others
    Morphactin Chlorflurenol methyl (Morphactin) is a plant growth regulator. Morphactin Chlorflurenol methyl preserves chlorophyll and suppresses senescence. Morphactin Chlorflurenol methyl regulates chlorophyll metabolic enzymes and alleviates heat-induced leaf senescence by enhancing chlorophyll content and reducing electrolyte leakage. Morphactin Chlorflurenol methyl promotes shoot redifferentiation and tracheary element development in tobacco calluses. Morphactin Chlorflurenol methyl can be applied to the investigation of heat-induced leaf senescence .
    Morphactin Chlorflurenol methyl
  • HY-N13282
    Glyceocarpin

    		Bacterial Fungal Infection
    Glyceocarpin is a phytoalexin and antibacterial agent naturally occurring in Glycine max, with weak antifungal activity. Glyceocarpin serves as the biosynthetic precursor of Glyceollins II (HY-N18032) and Glyceollins III. Glyceocarpin can be biosynthesized by the prenyltransferase and subsequent modification by cytochrome P450 enzymes. Glyceocarpin can be used for the study of soybean root and stem rot caused by Phytophthora sojae .
    Glyceocarpin
  • HY-N17580
    Lyciumin D

    		Renin Cardiovascular Disease
    Lyciumin D acts as an angiotensin-converting enzyme inhibitor and renin inhibitor. Lyciumin D can be used for the research of hypertension .
    Lyciumin D

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: