α-Cembrenediol
(Synonyms: α-CBD)
Customer Review
Based on 1 Customer Validation
α-Cembrenediol is a potent inhibitor of EBV.α-Cembrenediol inhibits the early antigen of the Epstein-Bar virus. α-Cembrenediol also has anti-tumour activity.
For research use only. We do not sell to patients.
- CAS No.: 57605-80-8
- Formula: C20H34O2
- Molecular Weight:306.48
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Size
Price
Stock
Quantity
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BT-474 | IC50 |
52.6 μM
Compound: 1
|
Antiproliferative activity against ER-positive human BT-474 cells overexpressing HER2 assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Antiproliferative activity against ER-positive human BT-474 cells overexpressing HER2 assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
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[PMID: 27681240] |
| BT-474 | IC50 |
67.1 μM
Compound: 1
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Antiproliferative activity against human BT474 cells by MTT assay
Antiproliferative activity against human BT474 cells by MTT assay
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[PMID: 28583806] |
| MCF-12A | IC50 |
70 μM
Compound: 1
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Cytotoxicity against human MCF12A cells by MTT assay
Cytotoxicity against human MCF12A cells by MTT assay
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[PMID: 28583806] |
| MCF7 | IC50 |
61.2 μM
Compound: 1
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Antiproliferative activity against estrogen-dependent human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Antiproliferative activity against estrogen-dependent human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
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[PMID: 27681240] |
| MDA-MB-231 | IC50 |
28.6 μM
Compound: 1
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Antimigratory activity against human MDA-MB-231 cells overexpressing c-Met assessed as inhibition of HGF-mediated cell migration measured after 23 hrs by wound healing assay
Antimigratory activity against human MDA-MB-231 cells overexpressing c-Met assessed as inhibition of HGF-mediated cell migration measured after 23 hrs by wound healing assay
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[PMID: 27681240] |
| MDA-MB-231 | IC50 |
34.3 μM
Compound: 1
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Antiproliferative activity against triple-negative human MDA-MB-231 cells overexpressing c-Met assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Antiproliferative activity against triple-negative human MDA-MB-231 cells overexpressing c-Met assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
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[PMID: 27681240] |
| MDA-MB-231 | IC50 |
37.6 μM
Compound: 1
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Antiinvasive activity against human MDA-MB-231 cells overexpressing c-Met assessed as inhibition of cell invasion measured after 24 hrs by Calcein AM dye based fluorescence assay
Antiinvasive activity against human MDA-MB-231 cells overexpressing c-Met assessed as inhibition of cell invasion measured after 24 hrs by Calcein AM dye based fluorescence assay
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[PMID: 27681240] |
| MDA-MB-468 | IC50 |
39.3 μM
Compound: 1
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Antiproliferative activity against triple-negative human MDA-MB-468 cells overexpressing c-Met assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Antiproliferative activity against triple-negative human MDA-MB-468 cells overexpressing c-Met assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
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[PMID: 27681240] |
| SK-BR-3 | IC50 |
48.9 μM
Compound: 1
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Antiproliferative activity against ER-deficient human SK-BR-3 cells overexpressing HER2 assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Antiproliferative activity against ER-deficient human SK-BR-3 cells overexpressing HER2 assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
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[PMID: 27681240] |
| T47D | IC50 |
61.9 μM
Compound: 1
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Antiproliferative activity against estrogen-dependent human T47D cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Antiproliferative activity against estrogen-dependent human T47D cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
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[PMID: 27681240] |
Chemical Information
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CAS No. 57605-80-8
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Appearance Solid
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Molecular Weight 306.48
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Formula C20H34O2
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Color White to off-white
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SMILES
O[C@@]1(C)C[C@@H](O)/C=C(C)/CC/C=C(C)/CC[C@@H](C(C)C)/C=C/1
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Synonyms
α-CBD
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
Select Batch:
Purity:
99.98%
Assay:
99.98%
ee.:
99.98%
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
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