494-52-0
Chemical Structure
Anabasine
Synonym(s): (S)-Anabasine; (+)-Anabasine
- CAS No.: 494-52-0
- Formula:C10H14N2
- Molecular Weight:162.24
IUPAC Name: (S)-3-(piperidin-2-yl)pyridine
InChIKey: MTXSIJUGVMTTMU-JTQLQIEISA-N
SMILES: C1([C@H]2NCCCC2)=CC=CN=C1
Biological Activity: Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM)[1][2].
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Anabasine | 99.02% | Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM). | ||||||||||||||||||||
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Anabasine (Standard) | ≥98% | Anabasine (Standard) is the analytical standard of Anabasine. This product is intended for research and analytical applications. Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM). | ||||||||||||||||||||
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- [1]. Levin ED, et al. Effects of tobacco smoke constituents, anabasine and anatabine, on memory and attention in female rats. J Psychopharmacol. 2014 Oct;28(10):915-22. [Content Brief]
- [2]. Benedict T Green, et al. Actions of piperidine alkaloid teratogens at fetal nicotinic acetylcholine receptors. Neurotoxicol Teratol. May-Jun 2010;32(3):383-90. [Content Brief]
Keywords
