21 Results for "

Nsf

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "Nsf" in MCE Product Catalog:

Referencia número: HY-P4113
Target:  

Inhibitory Antibodies

Áreas de investigación:  

Neurological Disease

TAT-NSF700 Fusion Peptide is a potent N-ethyl-maleimide-sensitive factor (NSF) inhibitor. TAT-NSF700 Fusion Peptide can readily permeate the cell membrane and interact with the intracellular organelle directly .
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Referencia número: HY-RS09591
Áreas de investigación:  

Others

NSF Human Pre-designed siRNA Set A contains three designed siRNAs for NSF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Referencia número: HY-P4114
Target:  

HIV

Áreas de investigación:  

Others

TAT-NSF700scr consists the intact TAT domain and glycine linker, followed by the NSF amino acids in a random order. TAT-NSF700scr is used as a control peptide that does not inhibit SNAREmediated exocytosis .
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Referencia número: HY-P4110
Target:  

iGluR

Áreas de investigación:  

Metabolic Disease Inflammation/Immunology

TAT-NSF222 Fusion Peptide is a fusion polypeptide with two domains, a TAT domain, which enters cells through macropinocytosis, and an NSF domain that inhibits N-ethylmaleimide-sensitive factor (NSF). TAT-NSF222 Fusion Peptide is an exocytosis inhibitor .
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Referencia número: HY-P4112
Target:  

Inhibitory Antibodies

Áreas de investigación:  

Others

TAT-NSF222scr Fusion Polypeptide, scrambled is a control peptide of TAT-NSF700 Fusion Peptide (HY-P4113). TAT-NSF222scr Fusion Polypeptide, scrambled is consisted of the intact TAT domain followed by the amino acid residues of NSF 222-243 in a scrambled order .
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Referencia número: HY-RS16783
Áreas de investigación:  

Others

Nsf Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nsf gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Referencia número: HY-P1399
No. CAS: 1423381-07-0
Synonyms: Myr-Pep2m
Target:  

PKC

Áreas de investigación:  

Neurological Disease

Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .
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Referencia número: HY-P1399A
Synonyms: Myr-Pep2m TFA
Target:  

PKC

Áreas de investigación:  

Neurological Disease

Pep2m, myristoylated TFA (Myr-Pep2m TFA) is a cell-permeable peptide. Pep2m, myristoylated TFA can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .
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Referencia número: HY-P1057
No. CAS: 243843-43-8
Target:  

iGluR

Áreas de investigación:  

Neurological Disease

Pep4c is an inactive control peptide for Pep2m (HY-P1058). Pep4c lacks functional activity to disrupt Protein Interacting with C Kinase 1 (PICK1)-AMPA receptor (GluA2) or N-ethylmaleimide-sensitive factor (NSF)-GluA2 interactions. Pep4c is used as a negative control in experiments to validate the specificity of Pep2m's effects on AMPA receptor trafficking and synaptic plasticity [1] [2] [3] [4] [5] [6].
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Referencia número: HY-RS23223
Áreas de investigación:  

Others

Nsf Rat Pre-designed siRNA Set A contains three designed siRNAs for Nsf gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Referencia número: HY-N12768
No. CAS: 37720-87-9
Rhodojaponin VI is an orally active diterpenoid compound found in hododendron molle G. Don
(Ericaceae) (RM). Rhodojaponin VI binds rat N-Ethylmaleimide-sensitive fusion (NSF) with a Kd of 1.03 μM. Rhodojaponin VI blocks the MDM2-Notch1 signalling pathway by reducing MDM2 and Notch1 expression. Rhodojaponin VI indirectly reduces Cav2.2 current intensity by inhibiting NSF-mediated Cav2.2 trafficking. Rhodojaponin VI alleviates glomerulonephritis progression and podocyte injury in passive heymann nephritis rats. Rhodojaponin VI also has antinociceptive effects. Rhodojaponin VI can be used for the researches of heymann nephritis and pain .
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Referencia número: HY-149590
No. CAS: 200348-48-7
Target:  

Phosphatase

Áreas de investigación:  

Others

IPA is a specific Sec18/NSF inhibitor. IPA binds to phosphatidic acid competitively, induces conformational rigidification of Sec18/NSF, disrupts its essential flexibility, and blocks SNARE priming and vacuolar membrane fusion. IPA can be used to investigate the activity of Sec18 and SNARE priming kinetics .
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Referencia número: HY-P811945
Synonyms: Skd2, Nsf, Vesicle-fusing ATPase, N-ethylmaleimide-sensitive fusion protein, Suppressor of K(+) transport growth defect 2, Vesicular-fusion protein Nsf, NEM-sensitive fusion protein, Protein SKD2

Host:  

Mouse

Application:  

WB, FC, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Referencia número: HY-P811945A
Synonyms: Skd2, Nsf, Vesicle-fusing ATPase, N-ethylmaleimide-sensitive fusion protein, Suppressor of K(+) transport growth defect 2, Vesicular-fusion protein Nsf, NEM-sensitive fusion protein, Protein SKD2

Host:  

Mouse

Application:  

WB, FC, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Referencia número: HY-P76504
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NAPG; SNAP-Gamma; Nsf Attachment Protein Gamma; Soluble Nsf Attachment Protein; Gamma-Soluble Nsf Attachment Protein; Gamma SNAP; N-Ethylmaleimide-Sensitive Factor Attachment Protein, Gamma; GAMMASNAP; N-Ethylmaleimide-Sensitive Factor Attachment Protein
Species:  
Human
Source:  
E. coli
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Referencia número: HY-P71326
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NAPA; N-Ethylmaleimide-Sensitive Factor Attachment Protein Alpha; Nsf Attachment Protein Alpha; Alpha Soluble Nsf Attachment Protein; N-Ethylmaleimide-Sensitive Factor Attachment Protein, Alpha; Alpha SNAP; Alpha-Soluble Nsf Attachment Protein; Alpha-SNAP
Species:  
Human
Source:  
E. coli
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Referencia número: HY-P811898
Synonyms: NAPB; Nsf Attachment Protein Beta; SNAPB; SNAP-BETA; N-Ethylmaleimide-Sensitive Factor Attachment Protein, Beta; Beta-Soluble Nsf Attachment Protein; N-Ethylmaleimide-Sensitive Factor Attachment Protein Beta; Beta Soluble Nsf Attachment Protein; SNAP-Beta; DEE107

Host:  

Mouse

Application:  

WB, FC

Reactivity:  

Human, Mouse, Rat

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Referencia número: HY-P811898A
Synonyms: NAPB; Nsf Attachment Protein Beta; SNAPB; SNAP-BETA; N-Ethylmaleimide-Sensitive Factor Attachment Protein, Beta; Beta-Soluble Nsf Attachment Protein; N-Ethylmaleimide-Sensitive Factor Attachment Protein Beta; Beta Soluble Nsf Attachment Protein; SNAP-Beta; DEE107

Host:  

Mouse

Application:  

WB, FC

Reactivity:  

Human, Mouse, Rat

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Referencia número: HY-P1058
No. CAS: 243843-42-7
Target:  

iGluR

Áreas de investigación:  

Neurological Disease

Pep2m is a peptide receptor inhibitor. Pep2m inhibits the interaction between the C-terminus of the AMPA-type glutamate receptor (GluA2) subunit and N-ethylmaleimide-sensitive fusion protein (NSF). Pep2m prevents synaptic long-term depression (LTD). Pep2m can reduce postsynaptic currents in neurons, AMPA-mediated currents in cultured hippocampal neurons, and AMPA receptor surface expression [1] [2] [3] [4] [5].
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Referencia número: HY-118460
No. CAS: 1135195-64-0
Synonyms: VCP/p97-IN-PPA
Target:  

p97

Áreas de investigación:  

Cancer

ACJI-99C (VCP/p97-IN-PPA) is a selective covalent p97/VCP ATPase inhibitor with an IC50 value of 0.6 μM. ACJI-99C binds with p97 active site residues to block ATPase activity. ACJI-99C irreversibly blocks degradation of p97-dependent protein in cells. ACJI-99C inhibits proliferation of cancer cells, including p97 inhibitor-resistant lines. ACJI-99C can be used for the research of colorectal cancer .
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