10 Results for "

Ornithine decarboxylase (ODC)

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "Ornithine decarboxylase (ODC)" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-N0240
CAS No.: 527-95-7
Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects . Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P71109
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ODC1; Alternative Protein ODC1; Ornithine decarboxylase 1; NEDBIA; ODC; NEDBA; Ornithine decarboxylase; BABS
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-B0744D
CAS No.: 69955-42-6
Synonyms: L-DFMO monohydrochloride; ; L-RMI71782 monohydrochloride; L-α-difluoromethylOrnithine monohydrochloride
Target:  

Parasite

Research Areas:  

Cancer

L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min -1 .
loading...
    loading...
Cat. No.: HY-W023493
CAS No.: 7685-44-1
Synonyms: 2-Aminopent-4-enoic acid
Research Areas:  

Neurological Disease

DL-Allylglycine (2-Aminopent-4-enoic acid) is a glutamate decarboxylase (GAD) inhibitor. DL-Allylglycine significantly increases mouse brain ornithine decarboxylase (ODC) activity and decreases S-adenosyl-L-methionine decarboxylase (SAM-DC) activity. DL-Allylglycine causes a marked decrease in brain GABA concentration. DL-Allylglycine has convulsant activity that can be used in studies to induce epileptic seizures .
loading...
    loading...
Cat. No.: HY-B0744C
CAS No.: 66640-93-5
Synonyms: L-DFMO; L-RMI71782; L-α-difluoromethylOrnithine
Target:  

Parasite

Research Areas:  

Cancer

L-Eflornithine (L-DFMO) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min -1 .
loading...
    loading...
Cat. No.: HY-W364575
CAS No.: 38030-58-9
Target:  

Drug Derivative

Research Areas:  

Cancer

Methyl-4-oxoretinoate is a derivative of Retinoic acid (HY-14649). Methyl-4-oxoretinoate inhibits TPA (HY-18739)-induced ornithine decarboxylase (ODC) activity, and carcinogen-induced papillomas in mouse skin .
loading...
    loading...
Cat. No.: HY-160843
CAS No.: 20584-81-0
Target:  

Apoptosis

Research Areas:  

Cancer

N-ω-chloroacetyl-L-ornithine (NCAO) is a potent reversible competitive ornithine decarboxylase (ODC) inhibitor that exerts cytotoxic and antiproliferative effects on tumor cell lines with EC50 values ranging from 1 to 50.6 µM. NCAO induces tumor cell Apoptosis and inhibits tumor cell migration in vitro. NCAO also exhibits a potent antitumor activity against both solid and ascitic tumors in a mouse model using the myeloma (Ag8) cell line. NCAO is promising for research of antitumor agents .
loading...
    loading...
Cat. No.: HY-N0240R
CAS No.: 527-95-7
Herbacetin (Standard) is the analytical standard of Herbacetin. This product is intended for research and analytical applications. Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects . Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis .
loading...
    loading...
Cat. No.: HY-100983R
CAS No.: 108930-17-2
Target:  

Reference Standards PKC

Research Areas:  

Cancer

Protein kinase inhibitor H-7 (dihydrochloride) (Standard) is the analytical standard of Protein kinase inhibitor H-7 (dihydrochloride). This product is intended for research and analytical applications. Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) .
loading...
    loading...
Cat. No.: HY-P702593
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ODC1; Alternative Protein ODC1; Ornithine decarboxylase 1; NEDBIA; ODC; NEDBA; Ornithine decarboxylase; BABS
Species:  
Human
Source:  
E. coli
loading...
    loading...