NCAO
Based on 1 Customer Validation
N-ω-chloroacetyl-L-ornithine (NCAO) is a potent reversible competitive ornithine decarboxylase (ODC) inhibitor that exerts cytotoxic and antiproliferative effects on tumor cell lines with EC50 values ranging from 1 to 50.6 µM. NCAO induces tumor cell Apoptosis and inhibits tumor cell migration in vitro. NCAO also exhibits a potent antitumor activity against both solid and ascitic tumors in a mouse model using the myeloma (Ag8) cell line. NCAO is promising for research of antitumor agents.
For research use only. We do not sell to patients.
- Purity: 98.07%
- CAS No.: 20584-81-0
- Formula: C7H13ClN2O3
- Molecular Weight:208.64
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Apoptosis Compound Library
HY-L003
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Anti-Cancer Compound Library
HY-L025
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Anti-Blood Cancer Compound Library
HY-L079
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Anti-Cancer Metabolism Compound Library
HY-L083
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Cell Death Library
HY-L162
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Anti-Hematopathy Compound Library
HY-L171
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MCE Bioactive Compound Library
HY-L001V
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Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library
HY-L199
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Chemical Information
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CAS No. 20584-81-0
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Appearance Solid
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Molecular Weight 208.64
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Formula C7H13ClN2O3
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Color White to off-white
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SMILES
OC([C@@H](N)CCCNC(CCl)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : ≥ 100 mg/mL (479.29 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.7929 mL | 23.9647 mL | 47.9294 mL | 119.8236 mL |
| 5 mM | 0.9586 mL | 4.7929 mL | 9.5859 mL | 23.9647 mL | |
| 10 mM | 0.4793 mL | 2.3965 mL | 4.7929 mL | 11.9824 mL | |
| 15 mM | 0.3195 mL | 1.5976 mL | 3.1953 mL | 7.9882 mL | |
| 20 mM | 0.2396 mL | 1.1982 mL | 2.3965 mL | 5.9912 mL | |
| 25 mM | 0.1917 mL | 0.9586 mL | 1.9172 mL | 4.7929 mL | |
| 30 mM | 0.1598 mL | 0.7988 mL | 1.5976 mL | 3.9941 mL | |
| 40 mM | 0.1198 mL | 0.5991 mL | 1.1982 mL | 2.9956 mL | |
| 50 mM | 0.0959 mL | 0.4793 mL | 0.9586 mL | 2.3965 mL | |
| 60 mM | 0.0799 mL | 0.3994 mL | 0.7988 mL | 1.9971 mL | |
| 80 mM | 0.0599 mL | 0.2996 mL | 0.5991 mL | 1.4978 mL | |
| 100 mM | 0.0479 mL | 0.2396 mL | 0.4793 mL | 1.1982 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
NCAO Related Classifications
HY-160843 Related Classifications
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