7685-44-1
Chemical Structure
DL-Allylglycine
Synonym(s): 2-Aminopent-4-enoic acid
- CAS No.: 7685-44-1
- Formula:C5H9NO2
- Molecular Weight:115.13
IUPAC Name: 2-aminopent-4-enoic acid
InChIKey: WNNNWFKQCKFSDK-UHFFFAOYSA-N
SMILES: C=CCC(N)C(O)=O
Biological Activity: DL-Allylglycine (2-Aminopent-4-enoic acid) is a glutamate decarboxylase (GAD) inhibitor. DL-Allylglycine significantly increases mouse brain ornithine decarboxylase (ODC) activity and decreases S-adenosyl-L-methionine decarboxylase (SAM-DC) activity. DL-Allylglycine causes a marked decrease in brain GABA concentration. DL-Allylglycine has convulsant activity that can be used in studies to induce epileptic seizures[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
DL-Allylglycine | 98.0% | DL-Allylglycine (2-Aminopent-4-enoic acid) is a glutamate decarboxylase (GAD) inhibitor. DL-Allylglycine significantly increases mouse brain ornithine decarboxylase (ODC) activity and decreases S-adenosyl-L-methionine decarboxylase (SAM-DC) activity. DL-Allylglycine causes a marked decrease in brain GABA concentration. DL-Allylglycine has convulsant activity that can be used in studies to induce epileptic seizures. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 1.00
HY-W012906L-Allylglycine -
Similarity Score 1.00
HY-W012907H-D-Gly(allyl)-OH -
Similarity Score 0.96
HY-34410(R)-2-Aminopent-4-enoic acid hydrochloride -
Similarity Score 0.96
HY-W015595L-Allylglycine hydrochloride -
Similarity Score 0.89
HY-W048220(S)-2-Aminohex-5-enoic acid -
Similarity Score 0.84
HY-W0129222-Methyl-4-pentenoic Acid -
Similarity Score 0.80
HY-W010589RL-2-Aminobutyric acid (Standard) -
Similarity Score 0.80
HY-W010590H-DL-Abu-OH -
Similarity Score 0.80
HY-Y0127D(-)-2-Aminobutyric acid -
Explore the MedChemAI to find more analogs
References
- [1]. Pajunen AE, et al. The effect of DL-allylglycine on polyamine and GABA metabolism in mouse brain. J Neurochem. 1979 May;32(5):1401-8. [Content Brief]
- [2]. Wada Y, et al. Effects of allylglycine on photosensitivity in the lateral geniculate-kindled cat. Exp Neurol. 1986 Oct;94(1):228-36. [Content Brief]
