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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
P388 cell lines
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "P388 cell lines" in MCE Product Catalog:
3
Category:
Labiatae Terpenoids Ulex europaeus L. Diterpenoids Plants Disease Research Fields Oxytropis falcata Bunge Cancer
Target:
Cat. No.: HY-18351
CAS No.: 915303-09-2
Synonyms: LMP-400; NSC-724998
Target:
Indotecan (LMP-400), an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis .
Cat. No.: HY-18351A
CAS No.: 1228035-68-4
Synonyms: LMP-400 hydrochloride; NSC-724998 hydrochloride
Target:
Indotecan hydrochloride, an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan hydrochloride prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis .
Cat. No.: HY-N6955
CAS No.: 757202-08-7
Category:
Melilotus albus Desr. Terpenoids Sesquiterpenes Plants Compositae Disease Research Fields Cancer
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Cat. No.: HY-N10208
CAS No.: 1216840-17-3
Category:
Natural Products Microorganisms Marine natural products Disease Research Fields Marine microorganism Cancer
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Cat. No.: HY-12458
CAS No.: 118292-36-7
Target:
Pyrindamycin A is an antibiotic that inhibits DNA synthesis. Pyrindamycin A shows antitumor activities against murine leukemia, exhibits stronger cytotoxic activities towards murine and human tumor cell lines and especially towards doxorubicin-resistant cells, inhibits P388 and P388/ADR cells with the same IC50 of 3.9 μg/ml .
Cat. No.: HY-N1655
CAS No.: 873999-88-3
Category:
Flavonoids Phenols Polyphenols Selaginella delicatula (Desv.) Alston Selaginellaceae Plants Disease Research Fields Biflavones Cancer
Target:
Cat. No.: HY-N3123
CAS No.: 28342-33-8
Synonyms: Dihydrooxochelerythrine
Target:
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Cat. No.: HY-167671
CAS No.: 135261-89-1
Category:
Target:
Cat. No.: HY-N15112
CAS No.: 138763-26-5
Category:
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Cat. No.: HY-N14144
CAS No.: 182285-29-6
Category:
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Cat. No.: HY-N14722
CAS No.: 182234-02-2
Category:
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Cat. No.: HY-N14530
CAS No.: 11050-22-9
Category:
Target:
Cat. No.: HY-117285
CAS No.: 60227-09-0
Synonyms: Lactoquinomycin A; LQM-A
Category:
Target:
Cat. No.: HY-N14774
CAS No.: 101342-94-3
Category:
Target:
Cat. No.: HY-N17754
CAS No.: 163136-31-0
Target:
Cat. No.: HY-123113
CAS No.: 65886-71-7
Synonyms: Kymarabine; Ara-AC; NSC 281272
Target:
Research Areas:
Fazarabine (Kymarabine; Ara-AC; NSC 281272) is an orally active, blood-brain barrier permeable DNA polymerase inhibitor and antitumor agent. Fazarabine interferes with DNA synthesis via intracellular activation into a triphosphate nucleotide that directly incorporates into DNA, inducing cytotoxicity, myelosuppression, as well as moderate nausea and vomiting. Fazarabine is resistant to deamination by cytidine-deoxycytidine deaminase and undergoes spontaneous aqueous degradation. Fazarabine exerts time-dependent, broad-spectrum activity against leukemia and solid tumors. Fazarabine can be used in research related to refractory malignancies, acute leukemia, and blast-phase chronic myeloid leukemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
