Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
141 Results for "
PDGF
" in MedChemExpress (MCE) Product Catalog:
Products (141)
141 Results for "PDGF" in MCE Product Catalog:
28
12
9
8
6
Category:
Cardiovascular Disease Uncaria rhynchophylla (Miq.) Miq. ex Havil. Alkaloids Rubiaceae Plants Disease Research Fields Indole Alkaloids
Target:
3
Category:
Quinones Leguminosae Anthraquinones Plants Cassia angustifolia Disease Research Fields Cancer
Target:
3
Research Areas:
Tyrphostin AG1296 is a potent and selective inhibitor of platelet-derived growth factor receptor (PDGFR), with an IC50 of 0.8 μM. Tyrphostin AG1296 inhibits signaling of human PDGF α- and β-receptors as well as of the related stem cell factor receptor (c-Kit). Tyrphostin AG1296 is also a potent inhibitor of FLT3, with an IC50 in the micromolar range .
3
2
2
2
1
1
1 Cited Publications
Synonyms: Bay 57-9352 mesylate
Telatinib mesylate (Bay 57-9352 mesylate) is a potent and orally active VEGFR2, VEGFR3, PDGFα, and c-Kit inhibitor with IC50s of 6 nM, 4 nM, 15 nM and 1 nM, respectively .
1
1
1 Cited Publications
Cat. No.: HY-P7055A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuPDGF-BB; PDGF-2; GDGF; ODGF; SIS; SSV
Species:
Source:
1
1
1 Cited Publications
Cat. No.: HY-P73351
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Platelet-derived growth factor subunit B; PDGF subunit B; PDGF2; PDGFB; SIS
Species:
Source:
1
1 Cited Publications
Cat. No.: HY-W011266
CAS No.: 627518-40-5
JNJ-10198409 is a relatively selective, orally active, and ATP competitive PDGF-RTK (platelet-derived growth factor receptor tyrosine kinase) inhibitor (IC50=2 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent. JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM) .
1
1 Cited Publications
Synonyms: Glucogallin; 1-O-Galloyl-β-D-glucose
1
1 Cited Publications
Cat. No.: HY-N2464
CAS No.: 34612-38-9
Synonyms: Amylotetraose; Fujioligo 450; α-1,4-Tetraglucose
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
