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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
PFAS
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "PFAS" in MCE Product Catalog:
Cat. No.: HY-DY3003
(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is a phosphonoformic acid (PFA) analog that exhibits higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) than PFA. (S)-Batylalcohol can be used in antiretroviral research .
Cat. No.: HY-W142432
CAS No.: 2058-94-8
Target:
Biochemical Assay Reagents β-catenin Wnt Arginase TGF-beta/Smad mTOR Akt ERK Atg8/LC3 p62 Autophagy
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Perfluoroundecanoic acid is a perfluoroalkyl substance (PFAS). Perfluoroundecanoic acid is an orally active oxidative stress inducer. Perfluoroundecanoic acid promotes macrophage M2 polarization, activates Wnt/β-catenin signaling and enhances β-catenin nuclear accumulation. Perfluoroundecanoic acid -induced M2 phenotype macrophage accelerates tumor progression in vitro and in vivo. Perfluoroundecanoic acid induces DNA damage, reproductive and pathophysiological dysfunctions via oxidative stress in male Swiss mice. Perfluoroundecanoic acid inhibits Leydig cell development in pubertal male rats via inducing oxidative stress and autophagy. Perfluoroundecanoic acid accelerates insulitis development in a mouse model of type 1 diabetes. Perfluoroundecanoic acid can be used for the study of ovarian cancer, type 1 diabetes and inflammation .
Cat. No.: HY-115701
CAS No.: 154436-49-4
Synonyms: 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine; 15(S)-HpETE-SAPE; 15(S)-hydroperoxyeicostetraenoic acid-SAPE
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1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-Pe (SAPE) by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.
Synonyms: 1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid; PFHpS
Perfluoroheptanesulfonic acid (1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid) is a perfluoroalkyl substance (PFAS). PFHpS can induce malformations in zebrafish larvae (EC50=168.1 μM). It has also been found in landfill leachate, and fetal exposure to PFHpS can lead to reduced birth weight.
Cat. No.: HY-W792491
CAS No.: 423-41-6
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Perfluoropropanesulfonic acid is an ultrashort-chain per- and polyfluoroalkyl substance (PFAS). Perfluoropropanesulfonic acid is an environmental pollutant .
Cat. No.: HY-W674169
CAS No.: 30334-69-1
Synonyms: FBSA
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Perfluorobutanesulfonamide (FBSA) is a per- and polyfluoroalkyl substance, which can be found as contaminant in wastewater .
Cat. No.: HY-W679758
CAS No.: 39108-34-4
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1H,1H,2H,2H-Perfluorodecanesulfonic acid (8:2 FTS) is a polyfluoroalkyl substance (PFAS) precursor .
Cat. No.: HY-W080797
CAS No.: 356-02-5
Synonyms: 3:3 FTCA
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4,4,5,5,6,6,6-Heptafluorohexanoic acid (3:3 FTCA) is a polyfluoroalkyl substance (PFAS) that accumulate in the environment. 3:3 FTCA binds to many proteins, including the primary human serum transport protein albumin (HSA) .
Cat. No.: HY-RS10357
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PFAS Human Pre-designed siRNA Set A contains three designed siRNAs for PFAS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19931
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Pfas Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pfas gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26433
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Pfas Rat Pre-designed siRNA Set A contains three designed siRNAs for Pfas gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28695
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Fnta Rat Pre-designed siRNA Set A contains three designed siRNAs for Fnta gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-181266
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Antimalarial agent 55 is an orally potent inhibitor of PfA-M1 and PfA-M17 aminopeptidases from Plasmodium falciparum, with Ki values of 27 nM and 81 nM, respectively. Antimalarial agent 55 exhibits potent nanomolar activity against homologous enzymes from Plasmodium vivax and Plasmodium berghei, with Ki values of 2 nM, 4 nM, 190 nM and 18 nM for Pv-M1, Pb-M1, Pv-M17 and Pb-M17, respectively. Antimalarial agent 55 possesses significant antiplasmodial activity, as well as cross-species inhibitory capacity and broad-spectrum activity that is unaffected by existing drug resistance mechanisms. Antimalarial agent 55 can be used in malaria research .
Cat. No.: HY-W142432S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
