1 Result for "

PIK-C98

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PIK-C98" in MCE Product Catalog:

Cat. No.: HY-12491
CAS No.: 691388-62-2
Target:  

PI3K Apoptosis

Research Areas:  

Cancer

PIK-C98 is a potent and selective PI3K inhibitor, with IC50s of 0.59, 1.64, 3.65, and 0.74 μM for α, β, δ, and γ isoforms, respectively. PIK-C98 inhibits all class I PI3Ks but has no effects on AKT or mTOR activity. PIK-C98 interferes with the ATP-binding pockets of PI3Ks by forming H-bonds and arene-H interactions with specific amino acid residues. PIK-C98 induces apoptosis by inhibiting PI3K. PIK-C98 can be used for the research of multiple myeloma .
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