1 Result for "

PT262

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PT262" in MCE Product Catalog:

Cat. No.: HY-100035
CAS No.: 86811-36-1
Purity:  99.21%
Target:  

ROCK ERK CDK Apoptosis

Research Areas:  

Cancer

PT-262 is a potent ROCK inhibitor with an IC50 value of around 5 μM. PT-262 induces the loss of mitochondrial membrane potential and elevates the caspase-3 activation and apoptosis. PT-262 inhibits the ERK and CDC2 phosphorylation via a p53-independent pathway. PT-262 blocks cytoskeleton function and cell migration. PT-262 has anti-cancer activity .
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