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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
Protein-arginine deiminase
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "Protein-arginine deiminase" in MCE Product Catalog:
Cat. No.: HY-P2966
CAS No.: 75536-80-0
Target:
Research Areas:
Protein-arginine deiminase is a unique family of enzymes that catalyzes the hydrolysis of peptidyl-arginine to form peptidyl-citrulline .
2
2 Cited Publications
Synonyms: PAD2-IN-1 hydrochloride
Target:
Research Areas:
AFM32a (PAD2-IN-1) hydrochloride, a benzimidazole-based derivative, is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. AFM32a hydrochloride shows superior selectivity for PAD2 over PAD4 (95-fold) and PAD3 (79-fold) .
1
1 Cited Publications
Cat. No.: HY-125099A
Purity: 99.83%
Target:
Research Areas:
AFM-30a hydrochloride is a potent protein arginine deiminase 2 (PAD2) inhibitor and has excellent PAD2-selectivity. AFM-30a hydrochloride binds to PAD2 with an EC50 value of 9.5 μM. AFM-30a hydrochloride also inhibits H3 citrullination with an EC50 value of 0.4 μM. AFM-30a hydrochloride can be used for the research of certain cancers and a variety of autoimmune diseases including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis .
1
1 Cited Publications
Cat. No.: HY-P70990
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI4; Protein-arginine deiminase Type IV; Prev. PADI5; HL-60 PAD; PDI5; PAD4; PDI4; Peptidyl arginine deiminase Type IV; PAD; Peptidylarginine deiminase IV; Peptidyl arginine deiminase, Type IV; PADI-H Protein; Peptidyl arginine deiminase, Type V; PADI4
Species:
Human
Source:
E. coli
Cat. No.: HY-143678
CAS No.: 2468149-70-2
Target:
Research Areas:
Citrulline-specific probe-biotin is a biotinylated probe for detection of citrulline. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-biotin is a biological probe that can identify diseases showing abnormal increases in PAD activity .
Cat. No.: HY-136557
CAS No.: 2095109-82-1
Synonyms: PAD2-IN-1
Target:
Research Areas:
AFM32a (PAD2-IN-1), a benzimidazole-based derivative, is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. AFM32a shows superior selectivity for PAD2 over PAD4 (95-fold) and PAD3 (79-fold) .
Cat. No.: HY-D1377
CAS No.: 2309313-01-5
Cat. No.: HY-P1417
CAS No.: 1345019-64-8
Synonyms: Thr-Asp-F-amidine
Target:
Research Areas:
Cat. No.: HY-126560
CAS No.: 877617-45-3
Target:
Research Areas:
F-Amidine is a Protein arginine deiminase 4 (PAD4) inhibitor. F-Amidine can be used in the study of inflammatory and immune system diseases (such as rheumatoid arthritis) .
Cat. No.: HY-125099
CAS No.: 2095107-57-4
Target:
Research Areas:
AFM-30a is a potent protein arginine deiminase 2 (PAD2) inhibitor and has excellent PAD2-selectivity. AFM-30a binds to PAD2 with an EC50 value of 9.5 μM. AFM-30a also inhibits H3 citrullination with an EC50 value of 0.4 μM. AFM-30a can be used for the research of certain cancers and a variety of autoimmune diseases including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis .
Cat. No.: HY-126560A
CAS No.: 877617-46-4
Target:
Research Areas:
F-Amidine TFA is a Protein arginine deiminase 4 (PAD4) inhibitor. F-Amidine TFA can be used in the study of inflammatory and immune system diseases (such as rheumatoid arthritis) .
Cat. No.: HY-139088
CAS No.: 1671088-84-8
Target:
Research Areas:
PAD3-IN-1 (compound 14b) is an inhibitor of protein arginine deiminase (PAD) and is more than 10-fold more selective for PAD3 than PAD 1, 2, and 4. The IC50 values of PAD3-IN-1 for PAD 1, 2, 3, and 4 are 120, 27.5, 4.5, and 30.5 μM, respectively. And PAD3 is a PAD isoform associated with neurodegenerative responses to spinal cord injury, and PAD3-IN-1 could be used to study PAD-related neurological diseases .
Cat. No.: HY-P704161
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI3; Protein-arginine deiminase Type-3; Peptidyl arginine deiminase 3; Peptidylarginine deiminase III; PDI3; PAD3; Peptidyl arginine deiminase, Type III; UHS1; Protein-arginine deiminase Type III
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703052
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI6; Protein-arginine deiminase Type VI; Peptidyl arginine deiminase 6; Peptidylarginine deiminase Type 6; Inactive Protein-arginine deiminase Type-6; Peptidylarginine deiminase VI; Peptidyl arginine deiminase-Like Protein; OZEMA16; Peptidyl arginine De
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704835
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PADI6; Protein-arginine deiminase Type VI; Peptidyl arginine deiminase 6; Peptidylarginine deiminase Type 6; Inactive Protein-arginine deiminase Type-6; Peptidylarginine deiminase VI; Peptidyl arginine deiminase-Like Protein; OZEMA16; Peptidyl arginine De
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-137124
CAS No.: 2219331-30-1
Target:
Research Areas:
BB-F-Yne is a protein arginine deiminase (PAD) inhibitor with Ki values of PAD1-4.are 2050, 1700, 1100, 3100 M -1min -1 respectively. BB-F-Yne can be used as a click probe to label PAD .
Cat. No.: HY-137125
CAS No.: 2219324-71-5
Target:
Research Areas:
BB-Cl-Yne is a protein arginine deiminase (PAD) inhibitor with Ki values of PAD1-4.are 6400, 3600, 10800, 4900 M -1min -1 respectively. BB-Cl-Yne can be used as a click probe to label PAD .
Cat. No.: HY-171002
Target:
Research Areas:
PAD2-IN-2 (cis-isomer of 1) is a protein arginine deiminase 2 (PAD2) inhibitor. PAD2-IN-2 possess an azobenzene photoswitch to optically control PAD activity. PAD2-IN-2 inhibits histone H3-citrullination .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
