209 Results for "

SARS-CoV-2 spike protein

" in MedChemExpress (MCE) Product Catalog:
Products (209)

209 Results for "SARS-CoV-2 spike protein" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P7436
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: 2019-nCoV RBD protein; 2019-nCoV spike RBD protein; S protein RBD; 2019-nCoV S protein RBD
Species:  
Virus
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-153083
Target:  

mRNA SARS-CoV

Research Areas:  

Infection

COVID-19 Spike Protein mRNA (N1-Me-Pseudo UTP) is an mRNA encoding the SARS-CoV-2 spike protein with enhanced performance via chemical modification. COVID-19 Spike Protein mRNA (N1-Me-Pseudo UTP) replaces natural uridine (UTP) with N1-Me-Pseudo UTP, which effectively reduces immunogenicity and improves stability and translation efficiency. The 3' UTR of COVID-19 Spike Protein mRNA (N1-Me-Pseudo UTP) optimizes AU-rich elements through HuR anchor sites, exhibiting higher translation efficiency. COVID-19 Spike Protein mRNA is widely used in COVID-19-related scientific research and vaccine development .
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1
1 Cited Publications
Cat. No.: HY-P99435
CAS No.: 2509447-07-6
Synonyms: BRII-196

Target:  

SARS-CoV

Research Areas:  

Infection

Amubarvimab (BRII-196) is a human IgG1 mAb that bind to non-competing epitopes on the receptor binding domain (RBD) of spike protein, with a KD of 5.88 nM. Amubarvimab can effectively neutralize SARS-CoV-2 variants .
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1
1 Cited Publications
Cat. No.: HY-P9801
Synonyms: SARS-CoV-2 (2019-nCoV) spike RBD Antibody

Target:  

SARS-CoV

Research Areas:  

Infection

Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody. Blocking the interaction of Spike protein and ACE2. Anti-Spike-RBD mAb is a potential therapeutic approach for SARS-CoV-2 treatment .
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1
1 Cited Publications
Cat. No.: HY-P73397
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: 2019-nCoV RBD protein; 2019-nCoV spike RBD protein; S protein RBD; 2019-nCoV S protein RBD
Species:  
Virus
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P78283
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: S protein RBD; S glycoprotein RBD; spike protein RBD
Species:  
Virus
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P99342
CAS No.: 2415933-40-1
Synonyms: REGN10987

Target:  

SARS-CoV

Research Areas:  

Infection

Imdevimab (REGN10987) is a human monoclonal antibody that targets SARS-CoV-2 virus. Imdevimab can be used in combination with Casirivimab (HY-P99341) to reduce viral load and transiently increases anti-receptor-binding domain IgG titers. Imdevimab maintains most of its neutralization activity against viruses with B.1.1.7, B.1.351 and mink cluster 5 spike proteins .
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Cat. No.: HY-P11146
CAS No.: 175483-64-4
Synonyms: Sakacin P inducer peptide
Target:  

Bacterial

Research Areas:  

Infection

SppIP (Sakacin P inducer peptide) is a peptide consisting of 19 amino acids . SppIP is an essential inducer for sakacin P production . SppIP can induce the expression of PRRSV GP5 and SARS-CoV-2 spike protein in recombinant Lactobacillus plantarum. SppIP can activate the transcription of the sakacin P promoter to drive the expression of downstream heterologous capsid proteins, increasing the proportion of PCV2d capsid proteins displayed on the cell surface of Lactobacillus plantarum. SppIP can be used in studies related to sakacin P induction .
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Cat. No.: HY-P99344
CAS No.: 2423943-37-5
Synonyms: Anti-Human SARS-CoV-2; LY-3819253; LY-CoV555

Target:  

SARS-CoV

Research Areas:  

Infection

Bamlanivimab (Anti-Human SARS-CoV-2; LY-CoV555) is an antiviral agent targeting the SARS-CoV-2 spike protein receptor-binding domain (RBD) with a mean Kd of 5.3 nM. Bamlanivimab binds epitopes overlapping the ACE2 binding site on both active and resting RBD conformations, blocks ACE2 attachment, mediates antibody-dependent cell-mediated cytotoxicity, and reduces viral replication and respiratory tract viral load. Bamlanivimab can be used for the research of COVID-19 .
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Cat. No.: HY-D1270
CAS No.: 2586-60-9
Direct Violet 1, an azo dye, is a textile dye. Direct Violet 1 is also the protein-protein interaction (PPI) between the SARS-CoV-2 spike protein and ACE2 inhibitor with IC50s of 1.47-2.63 μM .
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Cat. No.: HY-P99467
CAS No.: 2423016-74-2
Synonyms: BMS 4182137; VIR 7832

Target:  

SARS-CoV

Research Areas:  

Infection

Beludavimab (BMS 4182137; VIR 7832) is a monoclonal antibody targeting the spike glycoprotein of SARS-CoV-2. Beludavimab binds to recombinant spike protein receptor-binding domain (S-RBD) with an EC50 value of 14.9 ng/mL and a Kd of 0.21 nM .
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Cat. No.: HY-P99889
CAS No.: 2509447-08-7
Synonyms: BRII-198

Target:  

SARS-CoV

Research Areas:  

Infection

Romlusevimab (BRII-198) is a neutralizing recombinant human IgG1 monoclonal antibody against the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) .
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Cat. No.: HY-169171
CAS No.: 3115287-13-0
Target:  

Cathepsin

Research Areas:  

Infection

Cathepsin L-IN-5 (D6-3) is a potent Cathepsin L (CatL) inhibitor with an IC50 of 0.27 nM. Cathepsin L-IN-5 effectively blocks the CatL function and substantially hinders the entry of the SARS-CoV-2 pseudovirus to cells by inhibiting the cleavage of the spike protein. Cathepsin L-IN-5 can be utilized in SARS-CoV-2 research .
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Cat. No.: HY-144647
CAS No.: 2766185-81-1
Target:  

SARS-CoV Virus Protease

Research Areas:  

Infection

SP inhibitor 1 (compound 34) is a selective SARS-CoV-2 spike protein (SP) inhibitor with an IC50 of 3.26 μM, >25 μM, >25 μM for SP, M pro and PL pro protein, respectively. SP inhibitor 1 is a vitro SARS-CoV-2 replication inhibitor at non-toxic concentrations (0.3250<5.98 μM). SP inhibitor 1 shows cellular antiviral activity .
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Cat. No.: HY-174373
CAS No.: 455304-63-9
Research Areas:  

Infection

SARS-CoV-2-IN-113 (Compound 24) is a sulfonohydrazide derivative against SARS-CoV-2 infection with an IC50 of 8.320 μM. SARS-CoV-2-IN-113 exerts potent antiviral effects by inhibiting the entry and replication of SARS-CoV-2, and downregulating the expression of genes and proteins such as Spike, ACE-2, and RdRp. SARS-CoV-2-IN-113 has high selectivity and low cytotoxicity, and can be used in the research of SARS-CoV-2 .
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Cat. No.: HY-P99929
CAS No.: 2531098-91-4
Synonyms: HFB-30132A

Target:  

SARS-CoV

Research Areas:  

Inflammation/Immunology

Enuzovimab (HFB-30132A) is a mAb against SARS-COV-2 Omicron. Enuzovimab binds to spike (S) protein with high affinity .
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Cat. No.: HY-175325
Research Areas:  

Infection

SARS-CoV-2-IN-116 (Compound (S,S)-4) is a highly selective angiotensin-converting enzyme 2 (ACE2) inhibitor (pIC50=7.61). SARS-CoV-2-IN-116 blocks the interaction between SARS-CoV-2 spike protein and ACE2. SARS-CoV-2-IN-116 is promising for research of COVID-19 .
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Cat. No.: HY-163029
Target:  

Cathepsin SARS-CoV

Research Areas:  

Infection

CTSLCTSB-IN-1 (compound 212-148) is a bispecific inhibitor of host viral spike cleaver proteins CTSL/CTSB and TMPRSS2 with IC50s of 2.13/64.07 nM and 1.38 μM, respectively. CTSLCTSB-IN-1 blocks two relevant SARS-CoV-2 viral entry pathways by inhibiting the viral spike cleavage and can be applied to anti-SARS-CoV-2 research .
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Cat. No.: HY-149256
CAS No.: 1282451-83-5
Target:  

SARS-CoV

Research Areas:  

Infection

PLpro/RBD-IN-1 (compound 5) is a dual SARS-CoV-2 PLpro and spike protein RBD inhibitor with IC50s of 7.197 μM and 8.673 μM, respectively .
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Cat. No.: HY-P10976
Target:  

SARS-CoV

Research Areas:  

Infection

Spike Glycoprotein (1147-1162) is a linear and broadly neutralizing peptide in the S2 protein of SARS-CoV-2. Spike Glycoprotein (1147-1162) is conserved across SARS-CoV, BatCoV RaTG13, SARS-CoV-2, and SARS-CoV-2 variants. Spike Glycoprotein (1147-1162)-targeting mAbs can neutralize both SARS-CoV-2 and SARS-CoV by preventing fusion between the virus and cell membrane. Spike Glycoprotein (1147-1162) can be used for universal vaccines against SARS-CoV-2 mutants research .
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