455304-63-9
Chemical Structure
SARS-CoV-2-IN-113
- CAS No.: 455304-63-9
- Formula:C14H14N2O5S
- Molecular Weight:322.34
InChIKey: CBTDPHJXQDKURW-OVCLIPMQSA-N
SMILES: CC1=CC=C(C=C1)S(=O)(N/N=C/C2=C(C(O)=C(C=C2)O)O)=O
Biological Activity: SARS-CoV-2-IN-113 (Compound 24) is a sulfonohydrazide derivative against SARS-CoV-2 infection with an IC50 of 8.320 μM. SARS-CoV-2-IN-113 exerts potent antiviral effects by inhibiting the entry and replication of SARS-CoV-2, and downregulating the expression of genes and proteins such as Spike, ACE-2, and RdRp. SARS-CoV-2-IN-113 has high selectivity and low cytotoxicity, and can be used in the research of SARS-CoV-2[1].
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SARS-CoV-2-IN-113 | SARS-CoV-2-IN-113 (Compound 24) is a sulfonohydrazide derivative against SARS-CoV-2 infection with an IC50 of 8.320 μM. SARS-CoV-2-IN-113 exerts potent antiviral effects by inhibiting the entry and replication of SARS-CoV-2, and downregulating the expression of genes and proteins such as Spike, ACE-2, and RdRp. SARS-CoV-2-IN-113 has high selectivity and low cytotoxicity, and can be used in the research of SARS-CoV-2. | |||||||||||||||||||||
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Keywords
