1 Result for "

SKNBE-2 cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SKNBE-2 cells" in MCE Product Catalog:

Cat. No.: HY-100604
CAS No.: 1146594-87-7
Purity:  ≥99.0%
Target:  

γ-secretase Amyloid-β

Research Areas:  

Neurological Disease

JNJ-40418677 is an orally active modulator of γ-secretase, can cross the blood-brain barrier. JNJ-40418677 inhibits Aβ42 and NS2B-NS3 protease, with IC50s of 200 nM and 3.9 μM, respectively. JNJ-40418677 displays good biological tolerance, can be use for Alzheimer’s disease research .
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